Abstract: Disclosed is a Lactobacillus plantarum and an application thereof in the production of urolithin A, belonging to the technical field of biology. The disclosure provides a Lactiplantibacillus plantarum CCFM1290 preserved in Guangdong Microbial Culture Collection Center (GDMCC) with a preservation number of GDMCC No: 62801 and a preservation date of Sep. 15, 2022. The L. plantarum CCFM1290 may convert ETs into various Uros represented by Uro-A. A fermented product or compound preparation provided by the disclosure may relieve muscle function damage. Compared with a control group, the fermented product and compound preparation may improve the swimming capability of Caenorhabditis elegans by 33.84% and 27.99%. Finally, Uro-type substances such as Uro-A obtained by this biosynthesis method may be applied to functional food development to achieve beneficial effects of delaying senescence, keeping muscles healthy, etc.

Abstract: The present disclosure relates to a Bifidobacterium longum CCFM1206 capable of producing sulforaphane and relieving inflammation, and belongs to the field of microbial technology. B. longum CCFM1206 provided by the present disclosure can convert glucoraphanin to sulforaphane, promoting the metabolism of glucoraphanin and the generation of sulforaphane in mammals. The B. longum CCFM1206 according to the present disclosure can be used alone or in combination with glucoraphanin to relieve weight loss during ulcerative colitis, reduce the release of pro-inflammatory factors from the colon, improve the colonic barrier function, relieve the splenomegaly due to systemic inflammation, reduce the levels of pro-inflammatory factors in the serum, reduce the levels of pro-inflammatory factors in the liver tissues and increase the levels of anti-inflammatory factors, and increase the levels of short-chain fatty acids.

Abstract: The present disclosure discloses a strain of highly organic zinc-enriched Bifidobacterium animalis capable of promoting growth and reproductive development, belonging to the technical field of microorganisms. The B. animalis CCFM1230 screened by the present disclosure can efficiently enrich inorganic zinc and convert same into organic zinc, which is better absorbed and utilized by organisms, and effectively promotes growth and reproductive development. Animal experiments have proved that zinc-rich B. animalis can promote the growth and reproductive development of male rat pups, exert higher biological activity than inorganic zinc, and meet the physiological requirements of zinc supplementation. According to the present disclosure, the B. animalis CCFM1230 can efficiently enrich inorganic zinc for the preparation of a probiotic preparation capable of promoting growth and reproductive development, and thus has great application prospects in the field of food or medicine.

Abstract: The disclosure discloses a strain of Bifidobacterium breve capable of preventing and relieving psoriasis and application thereof, belonging to the field of microbial technologies and medical technologies. The disclosure provides new uses of B. breve CCFM1078 in inhibiting the release of IL-23/Th17 axis related inflammatory factors, and relieving the psoriasis. The B. breve CCFM1078 of the disclosure can relieve the lesion skin of psoriasis-like mice, and can inhibit thickening of the skin epidermal layer, so that the IL-23 level, the IL-22 level and the IL-17 level in the skin decrease by 20.3%, 22.0% and 18.3%, respectively. The B. breve CCFM1078 has a great application prospect in the preparation of a product (such as a food, a drug or a health food) for preventing and/or treating psoriasis.

Abstract: The present disclosure discloses multifunctional lactobacilli capable of relieving a toxic effect of perfluorooctanoic acid (PFOA) and use thereof, and belongs to the technical field of microorganisms.