Patents by Inventor Binh Thanh Vu

Binh Thanh Vu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CIS-imidazoles
    Publication number: 20040259867
    Abstract: The present invention provides compounds according to formula I and pharmaceutically acceptable salts and esters thereof, having the designations provided herein and which inhibit the interaction of MDM2 protein with a p53-like peptide and have antiproliferative activity.
    Type: Application
    Filed: June 15, 2004
    Publication date: December 23, 2004
    Inventors: Nader Fotouhi, Emily Aijun Liu, Binh Thanh Vu
  • CIS-imidazolines
    Publication number: 20040204410
    Abstract: The present invention provides compounds according to formula I and formula II and pharmaceutically acceptable salts and esters thereof, having the designations provided herein and which inhibit the interaction of MDM2 protein with a p53-like peptide and have antiproliferative activity.
    Type: Application
    Filed: April 28, 2004
    Publication date: October 14, 2004
    Inventors: Norman Kong, Emily Aijun Liu, Binh Thanh Vu
  • 4-aminopyrimidine-5-one derivatives
    Publication number: 20040162303
    Abstract: Novel 4-aminopyrimidine-5-one derivatives are disclosed. These compounds inhibit cyclin-dependent kinases, in particular cyclin-dependent kinase 4 (Cdk4). These compounds and their pharmaceutically acceptable salts and esters have antiproliferative activity and are useful in the treatment or control of cancer, in particular solid tumors. This invention is also directed to pharmaceutical compositions containing such compounds and to methods of treating or controlling cancer, most particularly the treatment or control of breast, lung, colon and prostate tumors. Also disclosed are intermediates useful in the preparation of these novel 4-aminopyrimidine-5-one derivatives.
    Type: Application
    Filed: February 2, 2004
    Publication date: August 19, 2004
    Inventors: David Joseph Bartkovitz, Xin-Jie Chu, Qingjie Ding, Nan Jiang, Allen John Lovey, John Anthony Moliterni, John Guilfoyle Mullin, Binh Thanh Vu, Peter Michael Wovkulich
  • Cis-imidazolines
    Patent number: 6734302
    Abstract: The present invention provides compounds according to formula I and formula II and pharmaceutically acceptable salts and esters thereof, having the designations provided herein and which inhibit the interaction of MDM2 protein with a p53-like peptide and have antiproliferative activity.
    Type: Grant
    Filed: December 11, 2002
    Date of Patent: May 11, 2004
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Norman Kong, Emily Aijun Liu, Binh Thanh Vu
  • Cis-imidazolines
    Patent number: 6617346
    Abstract: The present invention provides compounds according to formula I and formula II and pharmaceutically acceptable salts and esters thereof, having the designations provided herein and which inhibit the interaction of MDM2 protein with a p53-like peptide and have antiproliferative activity
    Type: Grant
    Filed: December 11, 2002
    Date of Patent: September 9, 2003
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Norman Kong, Emily Aijun Liu, Binh Thanh Vu
  • Cis-imidazolines
    Publication number: 20030153580
    Abstract: The present invention provides compounds according to formula I and formula II and pharmaceutically acceptable salts and esters thereof, having the designations provided herein and which inhibit the interaction of MDM2 protein with a p53-like peptide and have antiproliferative activity.
    Type: Application
    Filed: December 11, 2002
    Publication date: August 14, 2003
    Inventors: Norman Kong, Emily Aijun Liu, Binh Thanh Vu