Patents by Inventor Binhua Zhou

Binhua Zhou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5863776
    Abstract: The present invention provides a method of preparing apoenzyme of a riboflavin-dependent enzyme, comprising the steps of: growing COS-7 cells in a riboflavin-free medium; introducing a cDNA encoding a riboflavin-dependent enzyme; and expressing said cDNA. Also provided is a method of screening for an inhibitor of a flavin dependent enzyme, comprising the steps of;contracting a potential inhibitor of a flavin dependent enzyme with the cell line of claim 7 in the presence of riboflavin, FMN or Fad; and measuring the enzymatic activity of the flavin dependent enzyme.
    Type: Grant
    Filed: September 17, 1996
    Date of Patent: January 26, 1999
    Assignee: Research Development Foundation
    Inventors: Creed W. Abell, Sau-Wah Kwan, Binhua Zhou, Duane A. Lewis
  • Patent number: 5756479
    Abstract: The present invention provides an inhibitor of monoamine oxidase comprising a modified synthetic flavin adenine dinucleotide compound. Also provided is a method of inhibiting monoamine oxidase enzymatic activity in a cell, comprising the step of contacting said cell with a pharmacologically effective dose of a modified synthetic flavin adenine dinucleotide compound. Further provided is a method of treating a brain pathophysiological state in an individual, comprising administering a therapeutically effective dose of a modified synthetic flavin adenine dinucleotide compound to said individual.
    Type: Grant
    Filed: May 24, 1995
    Date of Patent: May 26, 1998
    Assignee: Research Development Foundation
    Inventors: Creed W. Abell, Sau-Wah Kwan, Binhua Zhou, Blain M. Mamiya, Duane A. Lewis