Patents by Inventor Bining Zhang

Bining Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Probes, microarray, primers, kit and applications for rapid detection of clinical ophthalmic microorganisms
    Patent number: 11891670
    Abstract: Disclosed are probes, primers, a microarray, a kit and applications for rapid detection of clinical microorganism in ophthalmology, belonging to that technical field of clinical microorganism detection. The probes of that disclosure comprise probes for respectively detect Staphylococcus epidermidis, Staphylococcus aureus, Staphylococcus haemolyticus, Pseudomonas aeruginosa, Staphylococcus hominis, Serratia marcescens, Escherichia coli, Bacillus subtilis and Enterobacter cloacae. The disclosure also discloses primers for amplifying the target bacteria, which comprises primers which can amplify gene sequence fragments with intra-species homology of more than 95 percent (%) and inter-species homology of less than 75%. The disclosure also provides a method for synthesizing the hybridization probe on the microarray, a method for hybridization reaction and a method for scanning detection.
    Type: Grant
    Filed: September 6, 2022
    Date of Patent: February 6, 2024
    Assignee: AFFILIATED EYE INSTITUTE OF SHANDONG FIRST MEDICAL UNIVERSITY
    Inventors: Yusen Huang, Bining Zhang, Wenfeng Li, Qing Liu, Zhichao Ren, Huabo Chen
  • PROBES, MICROARRAY, PRIMERS, KIT AND APPLICATIONS FOR RAPID DETECTION OF CLINICAL OPHTHALMIC MICROORGANISMS
    Publication number: 20230008908
    Abstract: Disclosed are probes, primers, a microarray, a kit and applications for rapid detection of clinical microorganism in ophthalmology, belonging to that technical field of clinical microorganism detection. The probes of that disclosure comprise probes for respectively detect Staphylococcus epidermidis, Staphylococcus aureus, Staphylococcus haemolyticus, Pseudomonas aeruginosa, Staphylococcus hominis, Serratia marcescens, Escherichia coli, Bacillus subtilis and Enterobacter cloacae. The disclosure also discloses primers for amplifying the target bacteria, which comprises primers which can amplify gene sequence fragments with intra-species homology of more than 95 percent (%) and inter-species homology of less than 75%. The disclosure also provides a method for synthesizing the hybridization probe on the microarray, a method for hybridization reaction and a method for scanning detection.
    Type: Application
    Filed: September 6, 2022
    Publication date: January 12, 2023
    Inventors: YUSEN HUANG, Bining Zhang, Wenfeng Li, Qing Liu, Zhichao Ren, Huabo Chen