Abstract: A non-transitory computer-readable medium stores instructions readable and executable by a workstation (18) including at least one electronic processor (20) to perform an imaging method (100). The method includes: estimating one or more figures of merit for a reconstructed image by applying a trained deep learning transform (30) to input data including at least imaging parameters and not including a reconstructed image; selecting values for the imaging parameters based on the estimated one or more figures of merit; generating a reconstructed image using the selected values for the imaging parameters; and displaying the reconstructed image.