Patents by Inventor Binuraj Krishnan Nair

Binuraj Krishnan Nair has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230364090
    Abstract: Disclosed are formulations/compositions comprising a BTK inhibitor, particularly ibrutinib: as well as processes for preparing such formulations/compositions and methods of treatment of a disease or condition that comprises the use of such formulations/compositions.
    Type: Application
    Filed: November 22, 2022
    Publication date: November 16, 2023
    Inventors: Manish Kumar Gupta, Parikshit Rameshrao Kulkarni, Binuraj Krishnan Nair
  • Publication number: 20230263804
    Abstract: Discussed herein are pharmaceutical compositions containing Ibrutinib and processes for preparing them. The compositions may be utilized in the treatment of a variety of conditions including, without limitation, B-cell proliferative disorders such as non-Hodgkin lymphoma (diffuse large B cell lymphoma, follicular lymphoma, mantle cell lymphoma or burkitt lymphoma), Waldenstrom macroglobulinemia, plasma cell myeloma, chronic lymphocytic leukemia, lymphoma, or leukemia. These compositions are designed for oral ingestion. The compositions are contained within a capsule such as a standard or sprinkle or in a liquid formulation such as a suspension. In one embodiment, the pharmaceutical composition contains Ibrutinib, a salt, prodrug, or metabolite thereof, microcrystalline cellulose, croscarmellose sodium, sodium lauryl sulfate, and magnesium stearate.
    Type: Application
    Filed: April 21, 2023
    Publication date: August 24, 2023
    Inventors: Manish Kumar Gupta, Kaustubh Tambwekar, Binuraj Krishnan Nair, Dilip J. Gole, Maristella Bernini, Sabine Inghelbrecht
  • Publication number: 20220339157
    Abstract: Disclosed are formulations/compositions comprising a BTK inhibitor, particularly ibrutinib (Formula I) as well as processes for preparing such formulations/compositions and methods of treatment of a disease or condition that comprises the use of such formulations/compositions.
    Type: Application
    Filed: May 4, 2022
    Publication date: October 27, 2022
    Inventors: Manish Kumar Gupta, Parikshit Rameshrao Kulkarni, Binuraj Krishnan Nair
  • Publication number: 20220211713
    Abstract: Discussed herein are pharmaceutical compositions containing Ibrutinib and processes for preparing them. The compositions may be utilized in the treatment of a variety of conditions including, without limitation, B-cell proliferative disorders such as non-Hodgkin lymphoma (diffuse large B cell lymphoma, follicular lymphoma, mantle cell lymphoma or burkitt lymphoma), Waldenstrom macroglobulinemia, plasma cell myeloma, chronic lymphocytic leukemia, lymphoma, or leukemia. These compositions are designed for oral ingestion. The compositions are contained within a capsule such as a standard or sprinkle or in a liquid formulation such as a suspension. In one embodiment, the pharmaceutical composition contains Ibrutinib, a salt, prodrug, or metabolite thereof, microcrystalline cellulose, croscarmellose sodium, sodium lauryl sulfate, and magnesium stearate.
    Type: Application
    Filed: March 29, 2022
    Publication date: July 7, 2022
    Inventors: Manish Kumar Gupta, Kaustubh Tambwekar, Binuraj Krishnan Nair, Dilip J. Gole, Maristella Bernini, Sabine Inghelbrecht
  • Publication number: 20210169888
    Abstract: Disclosed are formulations/compositions comprising a BTK inhibitor, particularly ibrutinib: as well as processes for preparing such formulations/compositions and methods of treatment of a disease or condition that comprises the use of such formulations/compositions.
    Type: Application
    Filed: February 11, 2021
    Publication date: June 10, 2021
    Inventors: Manish Kumar Gupta, Parikshit Rameshrao Kulkarni, Binuraj Krishnan Nair
  • Publication number: 20200171036
    Abstract: Discussed herein are pharmaceutical compositions containing Ibrutinib and processes for preparing them. The compositions may be utilized in the treatment of a variety of conditions including, without limitation, B-cell proliferative disorders such as non-Hodgkin lymphoma (diffuse large B cell lymphoma, follicular lymphoma, mantle cell lymphoma or burkitt lymphoma), Waldenstrom macroglobulinemia, plasma cell myeloma, chronic lymphocytic leukemia, lymphoma, or leukemia. These compositions are designed for oral ingestion. The compositions are contained within a capsule such as a standard or sprinkle or in a liquid formulation such as a suspension. In one embodiment, the pharmaceutical composition contains Ibrutinib, a salt, prodrug, or metabolite thereof, microcrystalline cellulose, croscarmellose sodium, sodium lauryl sulfate, and magnesium stearate.
    Type: Application
    Filed: December 10, 2019
    Publication date: June 4, 2020
    Inventors: Manish Kumar Gupta, Kaustubh Tambwekar, Binuraj Krishnan Nair, Dilip J. Gole, Maristella Bernini, Sabine Inghelbrecht
  • Publication number: 20190290650
    Abstract: Disclosed are formulations/compositions comprising a BTK inhibitor, particularly ibrutinib: as well as processes for preparing such formulations/compositions and methods of treatment of a disease or condition that comprises the use of such formulations/compositions.
    Type: Application
    Filed: January 18, 2017
    Publication date: September 26, 2019
    Inventors: Manish Kumar Gupta, Parikshit Rameshrao Kulkami, Binuraj Krishnan Nair
  • Publication number: 20190282577
    Abstract: Disclosed are formulations/compositions comprising a BTK inhibitor, particularly ibrutinib: as well as processes for preparing such formulations/compositions and methods of treatment of a disease or condition that comprises the use of such formulations/compositions.
    Type: Application
    Filed: January 18, 2017
    Publication date: September 19, 2019
    Inventors: Manish Kumar Gupta, Parikshit Rameshrao Kulkarni, Binuraj Krishnan Nair
  • Publication number: 20170252344
    Abstract: Discussed herein are pharmaceutical compositions containing Ibrutinib and processes for preparing them. The compositions may be utilized in the treatment of a variety of conditions including, without limitation, B-cell proliferative disorders such as non-Hodgkin lymphoma (diffuse large B cell lymphoma, follicular lymphoma, mantle cell lymphoma or burkitt lymphoma), Waldenstrom macroglobulinemia, plasma cell myeloma, chronic lymphocytic leukemia, lymphoma, or leukemia. These compositions are designed for oral ingestion. The compositions are contained within a capsule such as a standard or sprinkle or in a liquid formulation such as a suspension. In one embodiment, the pharmaceutical composition contains Ibrutinib, a salt, prodrug, or metabolite thereof, microcrystalline cellulose, croscarmellose sodium, sodium lauryl sulfate, and magnesium stearate.
    Type: Application
    Filed: May 23, 2017
    Publication date: September 7, 2017
    Inventors: Manish Kumar Gupta, Kaustubh Tambwekar, Binuraj Krishnan Nair, Dilip J. Gole, Maristella Bernini, Sabine Inghelbrecht
  • Publication number: 20160287594
    Abstract: Discussed herein are pharmaceutical compositions containing Ibrutinib and processes for preparing them. The compositions may be utilized in the treatment of a variety of conditions including, without limitation, B-cell proliferative disorders such as non-Hodgkin lymphoma (diffuse large B cell lymphoma, follicular lymphoma, mantle cell lymphoma or burkitt lymphoma), Waldenstrom macroglobulinemia, plasma cell myeloma, chronic lymphocytic leukemia, lymphoma, or leukemia. These compositions are designed for oral ingestion. The compositions are contained within a capsule such as a standard or sprinkle or in a liquid formulation such as a suspension. In one embodiment, the pharmaceutical composition contains Ibrutinib, a salt, prodrug, or metabolite thereof, microcrystalline cellulose, croscarmellose sodium, sodium lauryl sulfate, and magnesium stearate.
    Type: Application
    Filed: April 6, 2016
    Publication date: October 6, 2016
    Inventors: Manish Kumar Gupta, Kaustubh Tambwekar, Binuraj Krishnan Nair, Dilip J. Gole, Maristella Bernini, Sabine Inghelbrecht