Patents by Inventor Bipan Kumar Deb

Bipan Kumar Deb has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Human neural precursor cells with inducible STIM1 knockdown
    Patent number: 11851676
    Abstract: Human Neural precursor cells (hNPCs)/cell lines derived from human pluripotent stem cells have been stably transduced with inducible lentiviral constructs for knockdown of STIM1 thereby changing their gene expression. The said Human Neural precursor cells (hNPCs)/cell lines has selectively inducible knockdown of STIM1 via stable transduction of lentiviral shRNA vector followed by Doxycycline treatment. Human Neural precursor cells (hNPCs)/cell lines with stable knockdown STIM1 exhibits attenuated SOCE with downregulation of genes associated with cell proliferation and upregulation of genes for neural differentiation.
    Type: Grant
    Filed: April 17, 2019
    Date of Patent: December 26, 2023
    Assignee: NATIONAL CENTRE FOR BIOLOGICAL SCIENCES
    Inventors: Renjitha Gopurappilly, Gaiti Hasan, Bipan Kumar Deb
  • HUMAN NEURAL PRECURSOR CELLS WITH INDUCIBLE STIM1 KNOCKDOWN
    Publication number: 20200017828
    Abstract: Human Neural precursor cells (hNPCs)/cell lines derived from human pluripotent stem cells have been stably transduced with inducible lentiviral constructs for knockdown of STIM1 thereby changing their gene expression. The said Human Neural precursor cells (hNPCs)/cell lines has selectively inducible knockdown of STIM1 via stable transduction of lentiviral shRNA vector followed by Doxycycline treatment. Human Neural precursor cells (hNPCs)/cell lines with stable knockdown STIM1 exhibits attenuated SOCE with downregulation of genes associated with cell proliferation and upregulation of genes for neural differentiation.
    Type: Application
    Filed: April 17, 2019
    Publication date: January 16, 2020
    Inventors: Renjitha Gopurappilly, Gaiti Hasan, Bipan Kumar Deb