Patents by Inventor Bipasha Bose

Bipasha Bose has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Establishment of a human embryonic stem cell line using mammalian cells
    Patent number: 7811817
    Abstract: Purified preparations of human embryonic stem cells with certain population-specific characteristics are disclosed. This preparation is characterized by the positive expression of the following pluripotent cell surface markers: SSEA-1 (?); SSEA-4 (+); TRA-1-60 (+); TRA-1-81 (+); alkaline phosphatase (+), as well as a set of ES cell markers including Oct-4, Nanog, Rex1, Sox2, Thy1, FGF4, ABCG2, Dppa5, UTF1, Cripto1, hTERT, Connexin-43 and Connexin-45. The cells of the preparation are negative for lineage specific markers like Keratin 8, Sox-1, NFH (ectoderm), MyoD, brachyury, cardiac-actin (mesoderm), HNF-3 beta, albumin, and PDX1 (endoderm). The cells of the preparation are human embryonic stem cells, have normal karyotypes, exhibit high telomerase activity and continue to proliferate in an undifferentiated state after continuous culture for over 40 passages.
    Type: Grant
    Filed: May 17, 2006
    Date of Patent: October 12, 2010
    Assignee: Reliance Life Sciences Pvt. Ltd.
    Inventors: Arundhati Mandal, Shabari Tipnis, Geeta Ravindran, Jayant Kulkarni, Ameet Patki, Rajarshi Pal, Bipasha Bose, Alam Firdos Kahn, Aparna Khanna
  • Establishment of a human embryonic stem cell line using mammalian cells
    Publication number: 20060286544
    Abstract: Purified preparations of human embryonic stem cells with certain population-specific characteristics are disclosed. This preparation is characterized by the positive expression of the following pluripotent cell surface markers: SSEA-1 (?); SSEA-4 (+); TRA-1-60 (+); TRA-1-81 (+); alkaline phosphatase (+), as well as a set of ES cell markers including Oct-4, Nanog, Rex1, Sox2, Thy1, FGF4, ABCG2, Dppa5, UTF1, Criptol, hTERT, Connexin-43 and Connexin-45. The cells of the preparation are negative for lineage specific markers like Keratin 8, Sox-1, NFH (ectoderm), MyoD, brachyury, cardiac-actin (mesoderm), HNF-3 beta, albumin, and PDX1 (endoderm). The cells of the preparation are human embryonic stem cells, have normal karyotypes, exhibit high telomerase activity and continue to proliferate in an undifferentiated state after continuous culture for over 40 passages.
    Type: Application
    Filed: May 17, 2006
    Publication date: December 21, 2006
    Inventors: Arundhati Mandal, Shabari Tipnis, Geeta Ravindran, Jayant Kulkarni, Ameet Patki, Rajarshi Pal, Bipasha Bose, Firdos Khan, Aparna Khanna