Abstract: Gel compositions are provided that can be utilized as carriers for beneficial agents when injected into a subject and which can provide sustained release of the beneficial agent over time. In particular, gel compositions containing an agent that renders the composition thixotropic to facilitate injection of the gel into a subject with minimal discomfort to the subject are described.

Abstract: A device for the serial ejection of at least two fluid components comprises a spacer (19) providing at least two states, i) a first state allowing a front piston (7) to be displaced forwards by action on a rear piston (17) while a fluid volume is retained in a rear chamber (5) and ii) a second state allowing the rear chamber to volumetrically shrink while fluid is transferred past (or through) the front piston thereby enabling the use of a liquid, initially provided in only the rear chamber, for the dual purposes of mixing and rinsing.

Abstract: The injection device comprises a housing designed or suitable for manual gripping, a container for a preparation attached/enclosed in the housing, an outlet for the preparation exposed with respect to the housing and a mechanism arranged for moving the preparation at least from the container through the outlet. The system comprises a set of at least two elements having different properties in at least one respect. The elements are designed for mechanical attachment to one and the same area part of the housing, one at the time. The method includes the steps of providing at least two elements having different properties in at least one respect, the elements being designed for mechanical attachment to one and the same area part of the housing, one at the time, selecting one element from the set, and attaching mechanically the selected element to said area part of the housing.

Abstract: A device for the serial ejection of at least two fluid components comprises a spacer (19) providing at least two states, i) a first state allowing a front piston (7) to be displaced forwards by action on a rear piston (17) while a fluid volume is retained in a rear chamber (5) and ii) a second state allowing the rear chamber to volumetrically shrink while fluid is transferred past (or through) the front piston thereby enabling the use of a liquid, initially provided in only the rear chamber, for the dual purposes of mixing and rinsing.

Abstract: The invention relates to a device for injecting a fluid including a pressure chamber for accommodating the fluid, a piston for expelling the fluid from the pressure chamber, a pressure mechanism for generating an expelling impulse or force, and a transfer body coupled to the pressure mechanism, wherein, in an initial position the transfer body is arranged at a distance away from a contact point for transferring a force or impulse onto the piston. The invention encompasses a method for injecting a fluid wherein a transfer body is freely accelerated for a distance and strikes a contact point thus generating an initial impulse or pressure to expel the fluid.

Abstract: The injection device comprises a housing designed or suitable for manual gripping, a container for a preparation attached/enclosed in the housing, an outlet for the preparation exposed with respect to the housing and a mechanism arranged for moving the preparation at least from the container through the outlet. The system comprises a set of at least two elements having different properties in at least one respect. The elements are designed for mechanical attachment to one and the same area part of the housing, one at the time. The method includes the steps of providing at least two elements having different properties in at least one respect, the elements being designed for mechanical attachment to one and the same area part of the housing, one at the time, selecting one element from the set, and attaching mechanically the selected element to said area part of the housing.

Abstract: Injector device, and method for its operation, for containers of syringe type, comprising a barrel of axially roughly constant cross-section, a front opening and at least one movable wall inserted in the barrel for displacement of a container content, the injector comprising a) a housing or housing part arranged to receive the container at least axially stationary, b) an integral or composite piston rod arrangement operable to displace the container movable wall at least in the forward direction and c) a track system for controlling or sequencing the piston rod movements, the track system comprising at least one cooperating track and follower, the cooperating track and follower being arranged stationary with respect to the housing and the piston rod respectively, or vice versa, and in cooperation allowing at least one forward for the piston rod. The track system comprises arrangements initiation, dose setting and expulsion of container content.

Abstract: A system of marked medical containers comprises at least two containers having different properties in at least one respect, and at least one machine-readable marking on each of the containers, each marking being designed to allow discrimination between the difference in properties. Each marking allows discrimination between the difference by having at least one area with different absorbence or reflectance when irradiated with radiation in non-visible frequency ranges. A specific container comprises a syringe cartridge type container for use with a preparation delivery device.

Abstract: The invention relates to an injector device for delivery of liquid from a high pressure source, and also to a method of performing such an injection. The device comprises a storage chamber 6, for the liquid or the liquid precursor components, comprising a storage barrel 16 with at least a section of substantially constant cross-section, defining a storage chamber axis, and a pressure chamber 4 comprising a pressure barrel 10 of substantially constant cross-section, defining a pressure chamber axis, for accommodation of at least one piston therein and having a front end opening 14 for ejection of the liquid. The pressure chamber being of sufficient strength to sustain the liquid pressure.

Abstract: The invention relates to an injector device for delivery of liquid from a high pressure source, and also to a method of performing such an injection. The device comprises a storage chamber 6, for the liquid or the liquid precursor components, comprising a storage barrel 16 with at least a section of substantially constant cross-section, defining a storage chamber axis, and a pressure chamber 4 comprising a pressure barrel 10 of substantially constant cross-section, defining a pressure chamber axis, for accommodation of at least one piston therein and having a front end opening 14 for ejection of the liquid. The pressure chamber being of sufficient strength to sustain the liquid pressure.

Abstract: The invention relates to an injector device for delivery of liquid from a high pressure source, and also to a method of performing such an injection. The device comprises a storage chamber 6, for the liquid or the liquid precursor components, comprising a storage barrel 16 with at least a section of substantially constant cross-section, defining a storage chamber axis, and a pressure chamber 4 comprising a pressure barrel 10 of substantially constant cross-section, defining a pressure chamber axis, for accommodation of at least one piston therein and having a front end opening 14 for ejection of the liquid. The pressure chamber being of sufficient strength to sustain the liquid pressure.

Abstract: A system of marked medical containers comprises at least two containers having different properties in at least one respect, and at least one machine-readable marking on each of the containers, each marking being designed to allow discrimination between the difference in properties. Each marking allows discrimination between the difference by having at least one area with different absorbence or reflectance when irradiated with radiation in non-visible frequency ranges. A specific container comprises a syringe cartridge type container for use with a preparation delivery device.

Abstract: A jet injector comprising a housing (1) to be pressurized and holding a medical drug and which is defined by an enclosing periphery wall (3) and a bottom wall (4) having an internal surface (5) facing the interior of the housing (1) and opposite external surface (6). The bottom wall (4) has a through, truncated cone-shaped aperture (8) extending between said internal (5) and external (6) surfaces and through which said medical drug is expelled from the housing (1) and transformed into a thin jet stream (18) penetrating the skin of said person to be treated. An insert (9) having an essentially cone-shaped body (10) is arranged to be inserted into said housing (1) such that a portion (13) of said cone-shaped body (10), the periphery wall (39) of which is essentially congruent to the wall (12) of said aperture (8), is received in said aperture (8).

Abstract: Provided is a method for operating a preparation delivery device wherein the device comprises a) a container for the preparation having, or being prepared for the arrangement of, an opening, b) a mechanism operable to deliver at least part of the preparation in the container through the opening, c) attachment means for connection of the container to the mechanism and d) a sensor system arranged to detect at least one predetermined property of the container or its content. The method comprises transmitting radiation towards the container position or a part thereof to allow the radiation to be affected by the container position, receiving at least a part of the affected radiation from at least an area part of the container position in a non-imaging way and comparing the characteristics of the received radiation with a predetermined characteristic representative for the predetermined property to establish whether or not the predetermined property of the container is present.

Abstract: A syringe type ampoule having a) a barrel with a front end and a rear end defining an axis therebetween, the barrel having substantially constant cross-section between the front end and the rear end, at least the front end ending in an opening, b) a sealer attached to the front end and sealing the opening, c) at least one piston movably and sealingly arranged within the barrel and d) a sleeve extending along at least a part of the barrel, the sleeve having a front part and a rear part, the front part being connected to the sealer. The barrel has a front end terminating in an edge surrounding the opening, the edge having an outer circumference substantially equal to the barrel outer circumference. The invention relates to methods and means for manufacture of pre-filled such ampoules or other ampoules.

Abstract: The invention relates to an injector device for delivery of liquid from a high pressure source, and also to a method of performing such an injection. The device comprises a storage chamber 6, for the liquid or the liquid precursor components, comprising a storage barrel 16 with at least a section of substantially constant cross-section, defining a storage chamber axis, and a pressure chamber 4 comprising a pressure barrel 10 of substantially constant cross-section, defining a pressure chamber axis, for accommodation of at least one piston therein and having a front end opening 14 for ejection of the liquid. The pressure chamber being of sufficient strength to sustain the liquid pressure.

Abstract: A syringe type ampoule having a) a barrel with a front end and a rear end defining an axis therebetween, the barrel having substantially constant cross-section between the front end and the rear end, at least the front end ending in an opening, b) a sealer attached to the front end and sealing the opening, c) at least one piston movably and sealingly arranged within the barrel and d) a sleeve extending along at least a part of the barrel, the sleeve having a front part and a rear part, the front part being connected to the sealer. The barrel has a front end terminating in an edge surrounding the opening, the edge having an outer circumference substantially equal to the barrel outer circumference. The invention relates to methods and means for manufacture of pre-filled such ampoules or other ampoules.

Abstract: In an electronically controlled injection device for the administering of one or more injections from an injection cartridge, the readying of the device for administrating and the subsequent administering therefrom are controlled by an electronic control unit. This control unit comprises a position or attitude sensor which transmits signals to the control unit such that said readying of the device optionally cannot take place unless the longitudinal axis of the injection cartridge is oriented in a predetermined direction.

Abstract: The invention relates to a device for injecting a fluid including a pressure chamber for accommodating the fluid, a piston for expelling the fluid from the pressure chamber, a pressure mechanism for generating an expelling impulse or force, and a transfer body coupled to the pressure mechanism, wherein, in an initial position the transfer body is arranged at a distance away from a contact point for transferring a force or impulse onto the piston. The invention encompasses a method for injecting a fluid wherein a transfer body is freely accelerated for a distance and strikes a contact point thus generating an initial impulse or pressure to expel the fluid.

Abstract: The invention relates to an injector device for delivery of liquid from a high pressure source, and also to a method of performing such an injection. The device comprises a storage chamber 6, for the liquid or the liquid precursor components, comprising a storage barrel 16 with at least a section of substantially constant cross-section, defining a storage chamber axis, and a pressure chamber 4 comprising a pressure barrel 10 of substantially constant cross-section, defining a pressure chamber axis, for accommodation of at least one piston therein and having a front end opening 14 for ejection of the liquid. The pressure chamber being of sufficient strength to sustain the liquid pressure.