Patents by Inventor Birgit Jung

Birgit Jung has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds for the treatment of inflammatory diseases
    Patent number: 7511045
    Abstract: Dihydrothienopyrimidines of formula 1 and the pharmacologically acceptable salts, enantiomers, racemates, hydrates, or solvates thereof, which are suitable for the treatment of respiratory or gastrointestinal complaints or diseases, inflammatory diseases of the joints, skin, or eyes, diseases of the peripheral or central nervous system or cancers, as well as pharmaceutical compositions which contain these compounds.
    Type: Grant
    Filed: April 20, 2006
    Date of Patent: March 31, 2009
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Christoph Hoenke, Birgit Jung, Domnic Martyres, Peter Nickolaus, Pascale Pouzet
  • Bicyclic heterocyclic compounds, pharmaceutical compositions containing these compounds, their use and process for preparing them
    Publication number: 20090036676
    Abstract: The present invention relates methods for treating disease conditions selected from the list consisting of benign or malignant tumors, diseases of the airways and lungs, diseases of the gastrointestinal tract, the bile duct and the gall bladder by administration to a patient in need thereof of a therapeutically effective amount of a bicyclic heterocyclic groups of general formula wherein said substituents are as defined herein.
    Type: Application
    Filed: February 26, 2008
    Publication date: February 5, 2009
    Inventors: Frank Himmelsbach, Birgit Jung, Flavio Solca
  • PHARMACEUTICAL COMPOSITIONS FOR TREATMENT OF RESPIRATORY AND GASTROINTESTINAL DISORDERS
    Publication number: 20090017036
    Abstract: The present invention relates to novel pharmaceutical compositions comprising at least one EGFR kinase inhibitor and at least one additional active compound selected from beta-2 mimetics, steroids, PDE-IV inhibitors, p38 MAP kinase inhibitors, NK1 antagonists and endothelin-antagonists, processes for preparing the compositions and the use thereof as medicament in the treatment of respiratory or gastrointestinal complaints, as well as inflammatory diseases of the joints, the skin or the eyes.
    Type: Application
    Filed: September 2, 2008
    Publication date: January 15, 2009
    Inventors: Birgit Jung, Frank Himmelsbach
  • Bicyclic heterocycles, medicaments containing these compounds, their use and processes for their preparation
    Patent number: 7456189
    Abstract: Compounds of the formula having an inhibitory action on the signal transduction mediated by tyrosine kinases, and being useful for the treatment of oncoses and of benign prostate hyperplasia (BPH), of diseases of the lung and of the airways. Exemplary compounds are: (R)-4-(1-Phenylethylamino)-6-[1-(tert-butyloxycarbonyl)piperidin-4-yloxy]-7-methoxy-quinazoline and (R)-4-(1-Phenylethylamino)-6-(piperidin-4-yloxy)-7-methoxyquinazoline dihydrochloride.
    Type: Grant
    Filed: September 23, 2004
    Date of Patent: November 25, 2008
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Frank Himmelsbach, Birgit Jung
  • Substituted pteridines for the treatment of inflammatory diseases
    Publication number: 20080153833
    Abstract: The invention relates to new pteridines which are suitable for the treatment of respiratory or gastrointestinal complaints or diseases, inflammatory diseases of the joints, skin or eyes, diseases of the peripheral or central nervous system or cancers, as well as pharmaceutical compositions which contain these compounds.
    Type: Application
    Filed: February 14, 2008
    Publication date: June 26, 2008
    Inventors: Horst Dollinger, Juergen Mack, Domnic Martyres, Birgit Jung, Peter Nickolaus
  • BICYCLIC HETEROCYCLES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS, THEIR USE AND PROCESSES FOR THE PREPARATION THEREOF
    Publication number: 20080103161
    Abstract: The present invention relates to bicyclic heterocycles of general formula wherein Ra, Rb, Rc, A, B, C, D, E and X are defined as in claim 1, the tautomers, the stereoisomers, the mixtures and the salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids which have valuable pharmacological properties, particularly an inhibitory effect on signal transduction mediated by tyrosine kinases, the use thereof for treating diseases, particularly tumoral diseases, as well as benign prostatic hyperplasia (BPH), diseases of the lungs and respiratory tract, and the preparation thereof.
    Type: Application
    Filed: December 19, 2007
    Publication date: May 1, 2008
    Inventors: Frank Himmelsbach, Birgit Jung, Flavio Solca
  • Dihydrothienopyrimidines for the Treatment of Inflammatory Diseases
    Publication number: 20080096882
    Abstract: The invention relates to new dihydrothienopyrimidine of formula 1, as well as pharmacologically acceptable salts, diastereomers, enantiomers, racemates, hydrates or solvates thereof, wherein X is SO or SO2, but preferably SO, and wherein R1, R2 and R3 have the meanings given in the description, and which are suitable for the treatment of respiratory or gastrointestinal complaints or diseases, inflammatory diseases of the joints, skin or eyes, diseases of the peripheral or central nervous system or cancers, as well as pharmaceutical compositions which contain these compounds.
    Type: Application
    Filed: April 18, 2007
    Publication date: April 24, 2008
    Inventors: Pascale Pouzet, Christoph Hoenke, Rolf Goeggel, Birgit Jung, Peter Nickolaus, Dennis Fiegen, Thomas Fox
  • Substituted Pteridines
    Publication number: 20070287704
    Abstract: The invention relates to new pteridines which are suitable for treating respiratory or gastrointestinal complaints or diseases, inflammatory diseases of the joints, skin or eyes, diseases of the peripheral or central nervous system and cancers. This invention also relates to pharmaceutical compositions containing these compounds.
    Type: Application
    Filed: May 22, 2007
    Publication date: December 13, 2007
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Horst Dollinger, Domnic Martyres, Juergen Mack, Rolf Goeggel, Birgit Jung, Peter Nickolaus
  • Compounds for the treatment of inflammatory diseases
    Publication number: 20070259846
    Abstract: Dihydrothienopyrimidines of formula 1 and the pharmacologically acceptable salts, enantiomers, racemates, hydrates, or solvates thereof, which are suitable for the treatment of respiratory or gastrointestinal complaints or diseases, inflammatory diseases of the joints, skin, or eyes, diseases of the peripheral or central nervous system or cancers, as well as pharmaceutical compositions which contain these compounds.
    Type: Application
    Filed: April 20, 2006
    Publication date: November 8, 2007
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Christoph Hoenke, Birgit Jung, Domnic Martyres, Peter Nickolaus, Pascale Pouzet
  • Bicyclic Heterocycles, Pharmaceutical Compositions Containing These Compounds, Their Use and Processes for Preparing Them
    Publication number: 20070185091
    Abstract: The present invention relates to bicyclic heterocycles of general formula wherein Ra to Rc, A to E and X are defined as in claim 1, the tautomers, stereoisomers and salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids or bases which have valuable pharmacological properties, in particular an inhibitory effect on signal transduction mediated by tyrosine kinases, their use in the treatment of diseases, especially tumoral diseases and diseases of the lungs and airways, and the preparation thereof.
    Type: Application
    Filed: April 12, 2007
    Publication date: August 9, 2007
    Applicant: Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventors: Frank Himmelsbach, Elke Langkopf, Thomas Metz, Flavio Solca, Birgit Jung, Anke Baum
  • Bicyclic heterocycles, drugs containing said compounds, the use thereof and method for preparing same
    Publication number: 20070135463
    Abstract: The present invention relates to bicyclic heterocycles of general formula their tautomers, their stereoisomers, their mixtures and their salts, in particular their physiologically acceptable salts with inorganic or organic acids, which have valuable pharmacological properties, in particular an inhibitory action on the signal transduction mediated by tyrosine kinases, their use for the treatment of illnesses, in particular of tumoral diseases and of benign prostatic hyperplasia (BPH), of diseases of the lung and of the airways, and the preparation thereof.
    Type: Application
    Filed: December 6, 2006
    Publication date: June 14, 2007
    Inventors: Frank Himmelsbach, Marco Santagostino, Birgit Jung, Rainer Soyka
  • Method of treating mucus hypersecretion
    Publication number: 20070123516
    Abstract: The invention relates to the use of p38 kinase inhibitors for the preparation of a pharmaceutical composition suitable for inhalation for the treatment of mucus hypersecretion. Furthermore the invention is directed to pharmaceutical compositions suitable for inhalation comprising p38 kinase inhibitors and to methods for the preparation thereof.
    Type: Application
    Filed: June 1, 2006
    Publication date: May 31, 2007
    Applicant: Boehringer Ingelheim Pharma GmbH & Co., KG
    Inventor: Birgit Jung
  • Bicyclic heterocycles, pharmaceutical compositions containing these compounds, their use and processes for preparing them
    Patent number: 7220750
    Abstract: The present invention relates to bicyclic heterocycles of general formula wherein Ra to Rc, A to E and X are defined as in claim 1, the tautomers, stereoisomers and salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids or bases which have valuable pharmacological properties, in particular an inhibitory effect on signal transduction mediated by tyrosine kinases, their use in the treatment of diseases, especially tumoral diseases and diseases of the lungs and airways, and the preparation thereof.
    Type: Grant
    Filed: December 10, 2001
    Date of Patent: May 22, 2007
    Assignee: Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventors: Frank Himmelsbach, Elke Langkopf, Thomas Metz, Flavio Solca, Birgit Jung, Anke Baum
  • Cytokine involved in epithelial-mesenchymal transition
    Publication number: 20070089176
    Abstract: The functional characterization of ILEI to be a novel cytokine involved in epithelial/mesenchymal transition and the identification of biologically active ILEI provides the basis for generating ILEI inhibitors, in particular anti-ILEI antibodies, that are useful in the therapy of cancer, fibrosis and COPD.
    Type: Application
    Filed: September 2, 2004
    Publication date: April 19, 2007
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Andreas Zoephel, Horst Ahorn, Birgit Jung, Renate Konopitzky, Karl-Heinz Heider, Norbert Kraut, Peter Seither, Thomas Waerner, Hartmut Beug, Martin Jechlinger, Ido Tamir, Andreas Weith, Stefan Gruenert
  • Bicyclic heterocycles, pharmaceutical compositions containing these compounds, their use and processes for preparing them
    Patent number: 7196091
    Abstract: The present invention relates to bicyclic heterocycles of general formula wherein Ra, Rb, Rc, Rd, X and n are defined as in claim 1, the tautomers, the stereoisomers, the mixtures thereof and the salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids which have valuable pharmacological properties, particularly an inhibiting effect on the signal transduction mediated by tyrosine kinases, their use in treating diseases, particularly tumoral diseases, as well as benign prostatic hyperplasia (BPH), diseases of the lungs and respiratory tract and the preparation thereof.
    Type: Grant
    Filed: June 3, 2004
    Date of Patent: March 27, 2007
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Frank Himmelsbach, Rainer Soyka, Birgit Jung
  • Use of Substituted Pteridines for the treatment of respiratory diseases
    Publication number: 20070015749
    Abstract: The invention relates to the use of pteridines for the treatment of inflammatory and obstructive respiratory complaints, preferably asthma or COPD, as well as pharmaceutical compositions containing these compounds.
    Type: Application
    Filed: September 19, 2006
    Publication date: January 18, 2007
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Peter NICKOLAUS, Christopher Meade, Domnic Martyres, Juergen Mack, Birgit Jung, Horst Dollinger, Georg Dahmann
  • Use of tyrosine kinase inhibitors for the treatment of inflammatory processes
    Publication number: 20070004720
    Abstract: The use of selected quinazolines for the treatment of diseases of the airways or lungs as well as other inflammatory diseases. Exemplary of the selected quinazolines are: (1) 4-[(3-chloro-4-fluoro-phenyl)amino]-6-[1-(tert.-butyloxycarbonyl)-piperidin-4-yloxy]-7-methoxy-quinazoline, (2) 4-[(3-chloro-4-fluoro-phenyl)amino]-6-(trans-4-amino-cyclohexan-1-yloxy)-7-methoxy-quinazoline, and (3) 4-[(3-chloro-4-fluoro-phenyl)amino]-6-(trans-4-methanesulphonylamino-cyclohexan-1-yloxy)-7-methoxy-quinazoline.
    Type: Application
    Filed: September 7, 2006
    Publication date: January 4, 2007
    Inventors: Birgit Jung, Hubert Pueschner
  • Bicyclic heterocyclic compounds, pharmaceutical compositions containing these compounds, their use and process for preparing them
    Publication number: 20060270672
    Abstract: The present invention relates methods for treating disease conditions selected from the list consisting of benign or malignant tumors, diseases of the airways and lungs, diseases of the gastrointestinal tract, the bile duct and the gall bladder by administration to a patient in need thereof of a therapeutically effective amount of a bicyclic heterocyclic groups of general formula wherein said substituents are as defined herein.
    Type: Application
    Filed: August 2, 2006
    Publication date: November 30, 2006
    Inventors: Frank Himmelsbach, Birgit Jung, Flavio Solca
  • Bicyclic heterocycles, pharmaceutical compositions containing these compounds, their use and processes for preparing them
    Publication number: 20060264450
    Abstract: The present invention relates to bicyclic heterocycles of general formula wherein Ra, Rb, Rc, Rd, X and n are defined as in claim 1, the tautomers, the stereoisomers, the mixtures thereof and the salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids which have valuable pharmacological properties, particularly an inhibiting effect on the signal transduction mediated by tyrosine kinases, their use in treating diseases, particularly tumoral diseases, as well as benign prostatic hyperplasia (BPH), diseases of the lungs and respiratory tract and the preparation thereof.
    Type: Application
    Filed: July 28, 2006
    Publication date: November 23, 2006
    Inventors: Frank Himmelsbach, Rainer Soyka, Birgit Jung
  • Compounds for the treatment of inflammatory diseases
    Publication number: 20060258861
    Abstract: Compounds of formula 1 and hetero derivatives thereof and the pharmacologically acceptable salts, enantiomers, racemates, hydrates, or solvates thereof, which are suitable for the treatment of respiratory or gastrointestinal complaints or diseases, inflammatory diseases of the joints, skin, or eyes, diseases of the peripheral or central nervous system or cancers, as well as pharmaceutical compositions which contain these compounds.
    Type: Application
    Filed: April 21, 2006
    Publication date: November 16, 2006
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Ralf Anderskewitz, Horst Dollinger, Rolf Goeggel, Birgit Jung, Joerg Kley, Juergen Mack, Peter Nickolaus, Rainer Walter