Patents by Inventor Birgit Koch

Birgit Koch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mouse models carrying a knock-out mutation of the QPCTL-gene
    Patent number: 9277737
    Abstract: A knock-out non-human animal, in particular a mouse, carrying a QPCTL knock-out mutation. Additionally, respective cells and cell lines and methods and compositions for evaluating agents that affect QPCTL, for use in compositions for the treatment of QPCTL-related diseases are disclosed.
    Type: Grant
    Filed: May 6, 2013
    Date of Patent: March 8, 2016
    Assignee: PROBIODRUG AG
    Inventors: Hans-Ulrich Demuth, Anett Stephan, Birgit Koch, Holger Cynis, Stephan Schilling, Reinhard Sedlmeier, Sigrid Graubner
  • Crystal structure of glutaminyl cyclase
    Patent number: 8859250
    Abstract: Novel crystal structures of human and murine glutaminyl cyclase (QC, EC 2.3.2.5), methods of preparing the crystals, as well as the use of said crystal structures for identifying inhibitors of human and murine glutaminyl cyclase.
    Type: Grant
    Filed: February 26, 2013
    Date of Patent: October 14, 2014
    Assignee: Probiodrug AG
    Inventors: Stephan Schilling, Jens-Ulrich Rahfeld, Birgit Koch, Michael Wermann, Christoph Parthier, David Ruiz-Carillo, Milton T. Stubbs
  • Crystal structure of glutaminyl cyclase
    Patent number: 8409837
    Abstract: A novel crystal structures of human and murine glutaminyl cyclase (QC, EC 2.3.2.5), methods of preparing the crystals, as well as the use of said crystal structures for identifying inhibitors of human and murine glutaminyl cyclase.
    Type: Grant
    Filed: August 19, 2011
    Date of Patent: April 2, 2013
    Assignee: Probiodrug AG
    Inventors: Stephan Schilling, Jens-Ulrich Rahfeld, Birgit Koch, Michael Wermann, Christoph Parthier, David Ruiz-Carillo, Milton T. Stubbs
  • CRYSTAL STRUCTURE OF GLUTAMINYL CYCLASE
    Publication number: 20120045815
    Abstract: A novel crystal structures of human and murine glutaminyl cyclase (QC, EC 2.3.2.5), methods of preparing the crystals, as well as the use of said crystal structures for identifying inhibitors of human and murine glutaminyl cyclase.
    Type: Application
    Filed: August 19, 2011
    Publication date: February 23, 2012
    Applicant: PROBIODRUG AG
    Inventors: Stephan Schilling, Jens-Ulrich Rahfeld, Birgit Koch, Michael Wermann, Christoph Parthier, David Ruiz-Carillo, Milton T. Stubbs
  • MOUSE MODELS CARRYING A KNOCK-OUT MUTATION OF THE QPCTL-GENE
    Publication number: 20100299766
    Abstract: A knock-out non-human animal, in particular a mouse, carrying a QPCTL knock-out mutation. Additionally, respective cells and cell lines and methods and compositions for evaluating agents that affect QPCTL, for use in compositions for the treatment of QPCTL-related diseases are disclosed.
    Type: Application
    Filed: May 19, 2010
    Publication date: November 25, 2010
    Applicant: PROBIODRUG AG
    Inventors: Hans-Ulrich Demuth, Anett Stephan, Birgit Koch, Holger Cynis, Stephan Schilling, Reinhard Sedlmeier, Sigrid Graubner