Patents by Inventor Birgitta G. Karlsson

Birgitta G. Karlsson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel chromogenic thrombin substrates
    Patent number: 4247454
    Abstract: A chromogenic substrate having the formula ##STR1## and salts thereof wherein R.sub.1 is H or OH, R.sub.2 is a chromophoric group, and n is 1, 2 or 3.
    Type: Grant
    Filed: July 9, 1979
    Date of Patent: January 27, 1981
    Assignee: AB Kabi
    Inventors: Bo T. af Ekenstam, Leif E. Aurell, Karl G. Claeson, Birgitta G. Karlsson
  • Assay of serine proteases using novel chromogenic enzyme substrates
    Patent number: 4214049
    Abstract: Method for the quantitative determination of serine proteases which includes contacting the substance for which the determination is desired with a diagnostically active chromogenic substrate with good stability and high specificity to serine proteases having the formula: H--D--A.sub.1 --A.sub.2 --A.sub.3 --NH--R or salts thereof, wherein A.sub.1 is Gly, Ala, Val, Leu, Ile, Pip, Pro, or Aze; A.sub.2 is Gly, Ala, Val, Leu, Ile, Pip, Pro, Aze, or Phe; A.sub.3 is Arg, Lys, or Orn, and R is a chromophoric group.
    Type: Grant
    Filed: October 27, 1978
    Date of Patent: July 22, 1980
    Assignee: AB Kabi
    Inventors: Bo T. af Ekenstam, Leif E. Aurell, Karl G. Claeson, Birgitta G. Karlsson, Stig I. Gustavsson, Gun A. Olausson
  • Novel chromogenic thrombin substrates
    Patent number: 4169015
    Abstract: Process for determining thrombin and thrombin-like enzymes employing a substrate having the formula: ##STR1## and salts thereof, wherein R.sub.1 is H or OH; R.sub.2 is a chromophoric group; the N-terminal amino acid is in the D configuration and n is 1, 2 or 3 provided along with the method of use.
    Type: Grant
    Filed: August 22, 1977
    Date of Patent: September 25, 1979
    Assignee: AB Kabi
    Inventors: Bo T. af Ekenstam, Leif E. Aurell, Karl G. Claeson, Birgitta G. Karlsson
  • Novel chromogenic enzyme substrates
    Patent number: 4137225
    Abstract: Diagnostically active chromogenic substrate with good stability and high specificity to serine proteases having the formula: H-D-A.sub.1 -A.sub.2 -A.sub.3 -NH-R or salts thereof, wherein A.sub.1 is Gly, Ala, Val, Leu, Ile, Pip, Pro, or Aze; A.sub.2 is Gly, Ala, Val, Leu, Ile, Pip, Pro, Aze, or Phe; A.sub.3 is Arg, Lys, or Orn, and R is a chromophoric group.
    Type: Grant
    Filed: March 20, 1978
    Date of Patent: January 30, 1979
    Assignee: Ab Kabi
    Inventors: Bo T. Af Ekenstam, Leif E. Aurell, Karl G. Claeson, Birgitta G. Karlsson, Stig I. Gustavsson, Gun A. Olausson