Patents by Inventor Birgitte Schjellerup Wulff
Birgitte Schjellerup Wulff has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220280611Abstract: The present invention relates to a solid composition comprising a PYY compound and a salt of N-(8-(2-hydroxybenzoyl)amino)caprylic acid and their use in medicine.Type: ApplicationFiled: August 6, 2020Publication date: September 8, 2022Inventors: Andreas Vegge, Birgitte Schjellerup Wulff, Birgitte Nissen, Soeren Oestergaard, Betty Lomstein Pedersen
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Patent number: 10583172Abstract: The invention relates to PYY compounds having the amino acid in the position corresponding to position 35 of hPYY(1-36) substituted with beta-homoarginine and derivatives thereof with a modifying group attached to the position corresponding to position 7 of hPYY(1-36). The compounds of the invention are selective Y2 receptor agonists. The invention also relates to pharmaceutical compositions comprising such PYY compounds and pharmaceutically acceptable excipients, as well as the medical use of the PYY compounds.Type: GrantFiled: November 13, 2014Date of Patent: March 10, 2020Assignee: Novo Nordisk A/SInventors: Soeren Oestergaard, Kilian Waldemar Conde Frieboes, Birgit Wieczorek, Jens Kaalby Thomsen, Birgitte Schjellerup Wulff
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Patent number: 10246497Abstract: The invention relates to PYY compounds having the amino acid in the position corresponding to position 30 of hPYY(1-36) substituted with tryptophan and derivatives thereof with a modifying group attached to the position corresponding to position 7 of hPYY(1-36). The compounds of the invention are selective Y2 receptor agonists. The invention also relates to pharmaceutical compositions comprising such PYY compounds and pharmaceutically acceptable excipients, as well as the medical use of the PYY compounds.Type: GrantFiled: November 13, 2014Date of Patent: April 2, 2019Assignee: Novo Nordisk A/SInventors: Soeren Oestergaard, Kilian Waldemar Conde Frieboes, Birgit Wieczorek, Jens Kaalby Thomsen, Birgitte Schjellerup Wulff, Carsten Jessen
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Patent number: 10005824Abstract: The invention relates to PYY compounds with the amino acid modifications 7Lys, 30Trp, and 31Leu, and in addition to these, 22Ile and/or 28Tyr, and derivatives thereof. The compounds of the invention are selective Y2 receptor agonists. The invention also relates to pharmaceutical compositions comprising such PYY compounds and pharmaceutically acceptable excipients, as well as the medical use of the PYY compounds.Type: GrantFiled: June 28, 2017Date of Patent: June 26, 2018Assignee: Novo Nordisk A/SInventors: Soeren Oestergaard, Carsten Jessen, Birgitte Schjellerup Wulff, Annika Sanfridson
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Publication number: 20170313750Abstract: The invention relates to PYY compounds with the amino acid modifications 7Lys, 30Trp, and 31Leu, and in addition to these, 22Ile and/or 28Tyr, and derivatives thereof. The compounds of the invention are selective Y2 receptor agonists. The invention also relates to pharmaceutical compositions comprising such PYY compounds and pharmaceutically acceptable excipients, as well as the medical use of the PYY compounds.Type: ApplicationFiled: June 28, 2017Publication date: November 2, 2017Inventors: Soeren Oestergaard, Carsten Jessen, Birgitte Schjellerup Wulff, Annika Sanfridson
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Publication number: 20160289283Abstract: The invention relates to PYY compounds having the amino acid in the position corresponding to position 30 of hPYY(1-36) substituted with tryptophan and derivatives thereof with a modifying group attached to the position corresponding to position 7 of hPYY(1-36). The compounds of the invention are selective Y2 receptor agonists. The invention also relates to pharmaceutical compositions comprising such PYY compounds and pharmaceutically acceptable excipients, as well as the medical use of the PYY compounds.Type: ApplicationFiled: November 13, 2014Publication date: October 6, 2016Applicant: Novo NordiskInventors: Soeren Oestergaard, Kilian Waldemar Conde Frieboes, Birgit Wieczorek, Jens Kaalby Thomsen, Birgitte Schjellerup Wulff, Carsten Jessen
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Publication number: 20160263197Abstract: The invention relates to PYY compounds having the amino acid in the position corresponding to position 35 of hPYY(1-36) substituted with beta-homoarginine and derivatives thereof with a modifying group attached to the position corresponding to position 7 of hPYY(1-36). The compounds of the invention are selective Y2 receptor agonists. The invention also relates to pharmaceutical compositions comprising such PYY compounds and pharmaceutically acceptable excipients, as well as the medical use of the PYY compounds.Type: ApplicationFiled: November 13, 2014Publication date: September 15, 2016Inventors: Soeren Oestergaard, Kilian Waldemar Conde Frieboes, Birgit Wieczorek, Jens Kaalby Thomsen, Birgitte Schjellerup Wulff
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Patent number: 9085637Abstract: The invention relates to PYY compounds having the amino acid in the position corresponding to position 30 of hPYY(1-36) substituted with tryptophan and derivatives thereof with a modifying group attached to the position corresponding to position 7 of hPYY(1-36). The compounds of the invention are selective Y2 receptor agonists. The invention also relates to pharmaceutical compositions comprising such PYY compounds and pharmaceutically acceptable excipients, as well as the medical use of the PYY compounds.Type: GrantFiled: November 13, 2014Date of Patent: July 21, 2015Assignee: Novo Nordisk A/SInventors: Soeren Oestergaard, Kilian Waldemar Conde Frieboes, Birgit Wieczorek, Jens Kaalby Thomsen, Birgitte Schjellerup Wulff, Carsten Jessen
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Publication number: 20150152150Abstract: The invention relates to PYY compounds having the amino acid in the position corresponding to position 30 of hPYY(1-36) substituted with tryptophan and derivatives thereof with a modifying group attached to the position corresponding to position 7 of hPYY(1-36). The compounds of the invention are selective Y2 receptor agonists. The invention also relates to pharmaceutical compositions comprising such PYY compounds and pharmaceutically acceptable excipients, as well as the medical use of the PYY compounds.Type: ApplicationFiled: November 13, 2014Publication date: June 4, 2015Inventors: Soeren Oestergaard, Kilian Waldemar Conde Frieboes, Birgit Wieczorek, Jens Kaalby Thomsen, Birgitte Schjellerup Wulff, Carsten Jessen
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Publication number: 20130012432Abstract: The present invention relates to novel peptide compounds which are effective in modulating one or more melanocortin receptor types, to the use of the compounds in therapy, to methods of treatment comprising administration of the compounds to patients in need thereof, and to the use of the compounds in the manufacture of medicaments. The compounds of the invention are of particular interest in relation to the treatment of obesity as well as a variety of diseases or conditions associated with obesity.Type: ApplicationFiled: February 28, 2011Publication date: January 10, 2013Applicant: Novo Nordisk A/SInventors: Kilian Waldemar Conde-Frieboes, Jane Spetzler, Ulrich Sensfuss, Birgitte Schjellerup Wulff, Henning Thoegersen, Jens Christian Norrild
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Publication number: 20120021973Abstract: The present invention relates to novel peptide compounds which are effective in modulating one or more melanocortin receptor types, to the use of the compounds in therapy, to methods of treatment comprising administration of the compounds to patients in need thereof, and to the use of the compounds in the manufacture of medicaments. The compounds of the invention are of particular interest in relation to the treatment of obesity as well as a variety of diseases or conditions associated with obesity.Type: ApplicationFiled: November 24, 2009Publication date: January 26, 2012Applicant: Novo Nordisk A/SInventors: Jesper F. Lau, Ulrich Sensfuss, Kilian Waldemar Conde-Frieboes, Birgitte Schjellerup Wulff
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Publication number: 20110028391Abstract: GLP-1(1-45) or a fragment or an analogue thereof can be used in the preparation of a medicament for peripheral administration in the suppression of appetite or induction of satiety.Type: ApplicationFiled: October 15, 2010Publication date: February 3, 2011Applicant: Novo Nordisk A/SInventors: Jens Juul Holst, Arne Vernon Astrup, Martin Edward Judge, Liselotte Bjerre Knudsen, Lars Thim, Birgitte Schjellerup Wulff
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Publication number: 20100173835Abstract: The present invention relates to novel peptide compounds which are effective in modulating one or more melanocortin receptor types, to the use of the compounds in therapy, to methods of treatment comprising administration of the compounds to patients in need thereof, and to the use of the compounds in the manufacture of medicaments. The compounds of the invention are of particular interest in relation to the treatment of obesity as well as a variety of diseases or conditions associated with obesity.Type: ApplicationFiled: November 25, 2009Publication date: July 8, 2010Applicant: Novo Nordisk A/SInventors: Jesper Lau, Ulrich Sensfuss, Kilian Waldemar Conde-Frieboes, Birgitte Schjellerup Wulff
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Publication number: 20100113363Abstract: GLP-1(1-45) or a fragment or an analogue thereof can be used in the preparation of a medicament for peripheral administration in the suppression of appetite or induction of satiety.Type: ApplicationFiled: January 4, 2010Publication date: May 6, 2010Applicant: Novo Nordisk A/SInventors: Jens Juul Holst, Arne Vernon Astrup, Martin Edward Judge, Liselotte Bjerre Knudsen, Lars Thim, Birgitte Schjellerup Wulff
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Publication number: 20100022446Abstract: The present invention relates to novel peptide compounds which are effective in modulating one or more melanocortin receptor types, to the use of the compounds in therapy, to methods of treatment comprising administration of the compounds to patients in need thereof, and to the use of the compounds in the manufacture of medicaments. The compounds of the invention are of particular interest in relation to the treatment of obesity as well as a variety of diseases or conditions associated with obesity.Type: ApplicationFiled: January 17, 2008Publication date: January 28, 2010Applicant: Novo Nordisk A/SInventors: Birgitte Schjellerup Wulff, Kirsten Raun, Birgit Sehested Hansen
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Publication number: 20090149387Abstract: GLP-1(1-45) or a fragment or an analogue thereof can be used in the preparation of a medicament for peripheral administration in the suppression of appetite or induction of satiety.Type: ApplicationFiled: February 12, 2009Publication date: June 11, 2009Applicant: Novo Nordisk A/SInventors: Jens Juul Holst, Arne Vernon Astrup, Martin Edward Judge, Liselotte Bjerre Knudsen, Lars Thim, Birgitte Schjellerup Wulff
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Patent number: 7517854Abstract: Small cyclic peptides of the formula X1-X2-X3-X4-X5-X6-X7-R1 comprising 7-12 amino acid residues are provided. Said peptides are MC4 receptor agonists, and thus useful in the treatment of obesity and related diseases.Type: GrantFiled: March 30, 2006Date of Patent: April 14, 2009Assignee: Novo Nordisk A/SInventors: Kilian Waldemar Conde-Frieboes, Ulrich Sensfuss, Kjeld Madsen, Nils Langeland Johansen, Leif Christensen, Thomas Kruse Hansen, Birgitte Schjellerup Wulff
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Patent number: 6908926Abstract: Disclosed is a novel class of substituted imidazole compounds, pharmaceutical compositions containing them and uses of these compounds in the treatment and/or prevention of diseases and disorders related to the histamine H3 receptor. More particularly, these compounds are useful for the treatment and/or prevention of diseases and disorders in which an interaction with the histamine H3 receptor is beneficial. These imidazoles compounds have the formula I wherein R1, R2, R3, R4, R5, R6, A, X, Y and Z are as defined in the specification.Type: GrantFiled: April 12, 2000Date of Patent: June 21, 2005Assignee: Novo Nordisk A/SInventors: Florencio Zaragoza Dörwald, Knud Erik Andersen, Tine Krogh Jørgensen, Bernd Peschke, Birgitte Schjellerup Wulff, Ingrid Pettersson, Klaus Rudolf, Dirk Stenkamp, Rudolf Hurnaus, Stephan Georg Müller, Bernd Krist
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Publication number: 20030232754Abstract: GLP-1(1-45) or a fragment or an analogue thereof can be used in the preparation of a medicament for peripheral administration in the suppression of appetite or induction of satiety.Type: ApplicationFiled: March 6, 2003Publication date: December 18, 2003Inventors: Jens Juul Holst, Arne Vernon Astrup, Martin Edward Judge, Liselotte Bjerre Knudsen, Lars Thim, Birgitte Schjellerup Wulff
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Patent number: 5912229Abstract: The present invention relates to appetite-suppressing peptides or an appetite-suppressing peptide-containing fraction for the treatment of obesity or type II diabetes.Type: GrantFiled: February 28, 1997Date of Patent: June 15, 1999Assignee: Novo Nordisk AlsInventors: Lars Thim, Birgitte Schjellerup Wulff, Martin Edward Judge, Ole Dragsbaek Madsen, Jens Juul Holst