Abstract: The present application relates generally to methods for treating glioblastoma, or glioblastoma multiforme (GBM), with substituted heterocyclic derivative 4-[2-(cyclopropylmethoxy)-5-methylsulfonylphenyl]-2-methylisoquinolin-1-one, or the pharmaceutically acceptable salt thereof.

Abstract: The present disclosure provides methods, pharmaceutical compositions, and kits for treating cancer in patients in need thereof. The methods comprise administering to a patient in need a BET (bromodomain and extra-terminal protein) inhibitor, or a pharmaceutically acceptable salt thereof, alone or in combination with one or more JAK inhibitors. Also provided are medicaments for use in treating cancer.

Abstract: A method of detecting the presence or absence of a particular medical condition for a patient. The method comprises acquiring at least one image of an area of interest of the patient's body and identifying a first region of interest within the at least one acquired image corresponding to a first anatomical structure of interest and a second region of interest within the at least one acquired image corresponding to a second anatomical structure of interest. The method further comprises evaluating the first and second regions of interest, detecting the presence or absence of the medical condition based on the evaluation of the first and second regions of interest, and generating an electrical signal indicative of the detected presence or absence of the medical condition.