Patents by Inventor Biswanath De

Biswanath De has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Heterocyclic metalloprotease inhibitors
    Publication number: 20030186958
    Abstract: The invention provides compounds of formula 1
    Type: Application
    Filed: February 6, 2003
    Publication date: October 2, 2003
    Applicant: The Procter & Gamble Company
    Inventors: Biswanath De, Stanislaw Pikul, Menyan Cheng, Neil Gregory Almstead, Randall Stryker Matthews, Michael George Natchus, Yetunde Olabisi Taiwo
  • Heterocyclic side chain containing metalloprotease inhibitors
    Publication number: 20030171400
    Abstract: The compounds have a structure according to the following Formula (I): 1
    Type: Application
    Filed: September 18, 2002
    Publication date: September 11, 2003
    Inventors: Stanislaw Pikul, Norman Eugene Ohler, Neil Gregory Almstead, Steven Karl Laughlin, Michael George Natchus, Biswanath De
  • Carbocyclic side chain containing metalloprotease inhibitors
    Publication number: 20030162778
    Abstract: The compounds have a structure according to the following Formula (I): 1
    Type: Application
    Filed: September 18, 2002
    Publication date: August 28, 2003
    Applicant: The Procter and Gamble Company
    Inventors: Michael George Natchus, Stanislaw Pikul, Neil Gregory Almstead, Matthew John Laufersweiler, Roger Gunnard Bookland, Joshua Spector Tullis, Biswanath De
  • Carbocyclic side chain containing, N-substituted metalloprotease inhibitors
    Publication number: 20030144292
    Abstract: The compounds have a structure according to the following Formula (I): 1
    Type: Application
    Filed: September 18, 2002
    Publication date: July 31, 2003
    Inventors: Michael George Natchus, Stanislaw Pikul, Neil Gregory Almstead, Matthew John Laufersweiler, Biswanath De
  • Difluorobutyric acid metalloprotease inhibitors
    Publication number: 20030139453
    Abstract: Compounds according to the following Formula (I): 1
    Type: Application
    Filed: September 18, 2002
    Publication date: July 24, 2003
    Applicant: The Procter & Gamble Company
    Inventors: Stanislaw Pikul, Glen Edward Mieling, Katherine King Mieling, Kelly Michelle Solinsky, Biswanath De, Neil Gregory Almstead, Michael George Natchus
  • Heterocyclic side chain containing, n-substituted metalloprotease inhibitors
    Publication number: 20030139414
    Abstract: Disclosed are compounds which are inhibitors of metalloproteases and which are effective in treating conditions characterized by excess activity of these enzymes.
    Type: Application
    Filed: September 13, 2002
    Publication date: July 24, 2003
    Applicant: The Procter & Gamble Company
    Inventors: Stanislaw Pikul, Norman Eugene Ohler, Neil Gregory Almstead, Steven Karl Laughlin, Michael George Natchus, Biswanath De, Paul Mitchell Hershberger
  • 6,7-Dihydro-5H-pyrazolo[1,2-a]pyrazol-1-ones which control inflammatory cytokines
    Publication number: 20030134867
    Abstract: The present invention relates to compound which are capable of preventing the extracellular release of inflammatory cytokines, said compounds, including all enantiomeric and diasteriomeric forms and pharmaceutically acceptable salts thereof, have the formula: 1
    Type: Application
    Filed: September 18, 2002
    Publication date: July 17, 2003
    Applicant: The Procter & Gamble Company
    Inventors: Michael Philip Clark, Matthew John Laufersweiler, Jane Far-Jine Djung, Michael George Natchus, Biswanath De
  • 1,3-Diheterocyclic metalloprotease inhibitors
    Publication number: 20030130271
    Abstract: The invention provides compounds of formula 1
    Type: Application
    Filed: August 27, 2002
    Publication date: July 10, 2003
    Applicant: The Procter & Gamble Company
    Inventors: Stanislaw Pikul, Kelly Lynn McDow-Dunham, Neil Gregory Almstead, Biswanath De, Michael George Natchus, Yetunde Olabisi Taiwo
  • C16 unsaturated FP-selective prostaglandins analogs
    Patent number: 6586463
    Abstract: Compounds having the general structure: which are useful for the treatment of a variety of diseases and conditions, such as bone disorders.
    Type: Grant
    Filed: September 4, 2001
    Date of Patent: July 1, 2003
    Assignee: The Procter & Gamble Company
    Inventors: Mitchell Anthony deLong, David Lindsey Soper, John August Wos, Biswanath De
  • Substituted cyclic amine metalloprotease inhibitors
    Publication number: 20030105153
    Abstract: The invention provides compounds which are useful as inhibitors of metalloproteases, and which are effective in treating conditions characterized by excess activity of these enzymes. In particular, the present invention relates to a compound having a structure according to Formula (I).
    Type: Application
    Filed: July 1, 2002
    Publication date: June 5, 2003
    Inventors: Michael George Natchus, Biswanath De, Stanislaw Pikul, Neil Gregory Almstead, Roger Gunnard Bookland, Yetunde Olabisi Taiwo, Menyan Cheng
  • Compound which inhibit the release of inflammatory cytokines
    Publication number: 20030105084
    Abstract: The present invention relates to compound which are capable of preventing the extracellular release of inflammatory cytokines, said compounds, including all enantiomeric and diasteriomeric forms and pharmaceutically acceptable salts thereof, have the formula: 1
    Type: Application
    Filed: September 18, 2002
    Publication date: June 5, 2003
    Applicant: The Procter & Gamble Company
    Inventors: Michael Philip Clark, Matthew John Laufersweiler, Jane Far-Jine Djung, Biswanath De
  • Triazole compounds useful in treating diseases associated with unwanted cytokine activity
    Publication number: 20030100558
    Abstract: The present invention relates to 4-aryl triazoles having the formula: 1
    Type: Application
    Filed: April 24, 2002
    Publication date: May 29, 2003
    Inventors: Joshua Spector Tullis, John Charles Van Rens, Michael Philip Clark, Benjamin Eric Blass, Michael George Natchus, Biswanath De
  • Substituted cyclic amine metalloprotease inhibitors
    Patent number: 6569855
    Abstract: The invention provides compounds which are useful as inhibitors of metalloproteases, and which are effective in treating conditions characterized by excess activity of these enzymes. In particular, the present invention relates to a compound having a structure according to Formula (I). Also disclosed are compounds, pharmaceutical compositions and methods of treating diseases characterized by metalloprotease activity using these compounds or the pharmaceutical compositions containing them.
    Type: Grant
    Filed: June 25, 2001
    Date of Patent: May 27, 2003
    Assignee: The Procter & Gamble Company
    Inventors: Michael George Natchus, Biswanath De, Stanislaw Pikul, Neil Gregory Almstead, Roger Gunnard Bookland, Yetunde Olabisi Taiwo, Menyan Cheng
  • Isoxazolone compounds useful in treating diseases associated with unwanted cytokine activity
    Publication number: 20030096814
    Abstract: Isoxazolone compounds having the generic structure: 1
    Type: Application
    Filed: May 7, 2002
    Publication date: May 22, 2003
    Inventors: Michael Philip Clark, Jane Far-Jine Djung, Steven Karl Laughlin, Joshua Spector Tullis, Michael George Natchus, Biswanath De
  • Hetero-substituted metalloprotease inhibitors
    Patent number: 6566381
    Abstract: Heterocyclic substituted compounds having the general structure: which are inhibitors of metalloproteases and which are effective in treating conditions characterized by excess activity of these enzymes.
    Type: Grant
    Filed: March 1, 2000
    Date of Patent: May 20, 2003
    Assignee: The Procter & Gamble Company
    Inventors: Menyan Cheng, Neil Gregory Almstead, Michael George Natchus, Stanislaw Pikul, Biswanath De
  • Spirocyclic-6,7-dihydro-5H-pyrazolo[1,2-a]pyrazol-1-ones which control inflammatory cytokines
    Patent number: 6566357
    Abstract: The present invention relates to compound which are capable of preventing the extracellular release of inflammatory cytokines, said compounds, including all enantiomeric and diasteriomeric forms and pharmaceutically acceptable salts thereof, have the formula: wherein R comprises ethers or amines; R1 is: a) substituted or unsubstituted aryl; or b) substituted or unsubstituted heteroaryl; two R2 units on the same carbon atom are taken together to form a spirocyclic ring having from 4 to 7 atoms, the balance of the R2 units are independently selected from the group consisting of: a) hydrogen; b) —O(CH2)jR8; c) —(CH2)jNR9aR9b; d) —(CH2)jCO2R10; e) —(CH2)jOCO2R10 f) —CH2)jCON(R10)2; and g) two R2 units can be taken together to form a carbonyl unit; R8, R9a, R9b, and R10 are each independently hydrogen, C1-C4 alkyl, and mixtures thereof; R9a and R9b can be taken together to form a carbocyclic or heterocyclic ring comprising from 3 to 7 atoms; two R10 uni
    Type: Grant
    Filed: September 18, 2002
    Date of Patent: May 20, 2003
    Assignee: The Procter & Gamble Co.
    Inventors: Matthew John Laufersweiler, Michael Philip Clark, Jane Far-Jine Djung, Adam Golebiowski, Todd Andrew Brugel, Biswanath De
  • Heterocyclic metalloprotease inhibitors
    Patent number: 6545038
    Abstract: The invention provides compounds of formula as described in the claims, or an optical isomer, diastereomer or enantiomer thereof, or a pharmaceutically-acceptable salt, or biohydrolyzable amide, ester, or imide thereof are useful as inhibitors of metalloproteases. Also disclosed are pharmaceutical compositions and methods of treating diseases, disorders and conditions characterized by metalloprotease activity using these compounds or the pharmaceutical compositions containing them.
    Type: Grant
    Filed: November 6, 2000
    Date of Patent: April 8, 2003
    Assignee: The Procter & Gamble Company
    Inventors: Biswanath De, Stanislaw Pikul, Menyan Cheng, Neil Gregory Almstead, Randall Stryker Matthews, Michael George Natchus, Yetunde Olabisi Taiwo
  • Triazole compounds useful in treating diseases associated with unwanted cytokine activity
    Publication number: 20030013712
    Abstract: The present invention relates to 4-aryl triazoles having the formula: 1
    Type: Application
    Filed: April 24, 2002
    Publication date: January 16, 2003
    Inventors: Joshua Spector Tullis, John Charles Van Rens, Michael Philip Clark, Benjamin Eric Blass, Michael George Natchus, Biswanath De
  • 1,3-diheterocyclic metalloprotease inhibitors
    Patent number: 6469000
    Abstract: Disclosed are compounds which are inhibitors of metalloproteases having the following structure: where Ar, W, X, Y, Z, R1 and R2 have the meanings described in the specification and optical isomers, diastereomers, and enantiomers thereof or a pharmaceutically-acceptable salt, or biohydrolyzable amides, esters, or imides thereof. Also disclosed are pharmaceutical compositions and methods of treating diseases, disorders and conditions characterized by unwanted metalloprotease activity using these compounds or pharmaceutical compositions.
    Type: Grant
    Filed: August 29, 2000
    Date of Patent: October 22, 2002
    Assignee: The Procter & Gamble Co.
    Inventors: Stanislaw Pikul, Kelly Lynn McDow-Dunham, Neil Gregory Almstead, Biswanath De, Michael George Natchus, Yetunde Olabisi Taiwo
  • 1,3-diheterocyclic metalloprotease inhibitors
    Patent number: 6465474
    Abstract: Disclosed are compounds which are inhibitors of metalloproteases having the following structure: where Ar, W, X, Y, Z, R1 and R2 have the meanings described in the specification and optical isomers, diastereomers, and enantiomers thereof or a pharmaceutically-acceptable salt, or biohydrolyzable amides, esters, or imides thereof. Also disclosed are pharmaceutical compositions and methods of treating diseases, disorders and conditions characterized by unwanted metalloprotease activity using these compounds or pharmaceutical compositions.
    Type: Grant
    Filed: August 29, 2000
    Date of Patent: October 15, 2002
    Assignee: The Procter & Gamble Company
    Inventors: Stanislaw Pikul, Kelly Lynn McDow-Dunham, Neil Gregory Almstead, Biswanath De, Michael George Natchus, Yetunde Olabisi Taiwo