Patents by Inventor Bjørn Gunnar Voldborg

Bjørn Gunnar Voldborg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GLYCOSYLATION OF PROTEINS
    Publication number: 20230272445
    Abstract: The present invention relates to the finding of methods to shift the glycosylation profile of recombinant produced serum glycoproteins to the predominant bi-antennary form found in human plasma. This is accomplished by providing a mammalian cell line according to the invention with a series of gene disruptions and/or gene insertions that facilitate this shift.
    Type: Application
    Filed: November 16, 2022
    Publication date: August 31, 2023
    Inventors: Bjørn Gunnar Voldborg, Stefan Kol, Anders Holmgaard Hansen, Helene Faustrup Kildegaard
  • Glycosylation of proteins
    Patent number: 11624080
    Abstract: The present invention relates to the finding of methods to shift the glycosylation profile of recombinant produced semm glycoproteins to the predominant bi-antennary form found in human plasma. This is accomplished by providing a mammalian cell line according to the invention with a series of gene disruptions and/or gene insertions that facilitate this shift.
    Type: Grant
    Filed: November 16, 2018
    Date of Patent: April 11, 2023
    Assignee: DANMARKS TEKNISKE UNIVERSITET
    Inventors: Bjørn Gunnar Voldborg, Stefan Kol, Anders Holmgaard Hansen, Helene Faustrup Kildegaard
  • GLYCOSYLATION OF PROTEINS
    Publication number: 20210262000
    Abstract: The present invention relates to the finding of methods to shift the glycosylation profile of recombinant produced semm glycoproteins to the predominant bi-antennary form found in human plasma. This is accomplished by providing a mammalian cell line according to the invention with a series of gene disruptions and/or gene insertions that facilitate this shift.
    Type: Application
    Filed: November 16, 2018
    Publication date: August 26, 2021
    Inventors: Bjørn Gunnar Voldborg, Stefan Kol, Anders Holmgaard Hansen, Helene Faustrup Kildegaard
  • Engineered mammalian cells for production of recombinant proteins
    Patent number: 10982191
    Abstract: The present invention relates to mammalian cells modified to provide for improved expression of a recombinant protein of interest. In particular, the invention relates to CHO cells and other host cells in which the expression of one or more endogenous secreted proteins has been disrupted, as well as to the preparation, identification and use of such cells in the production of recombinant proteins.
    Type: Grant
    Filed: April 25, 2017
    Date of Patent: April 20, 2021
    Assignees: DANMARKS TEKNISKE UNIVERSITET, THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Bjørn Gunnar Voldborg, Lasse Ebdrup Pedersen, Bernhard Palsson
  • ENGINEERED MAMMALIAN CELLS FOR PRODUCTION OF RECOMBINANT PROTEINS
    Publication number: 20190136198
    Abstract: The present invention relates to mammalian cells modified to provide for improved expression of a recombinant protein of interest. In particular, the invention relates to CHO cells and other host cells in which the expression of one or more endogenous secreted proteins has been disrupted, as well as to the preparation, identification and use of such cells in the production of recombinant proteins.
    Type: Application
    Filed: April 25, 2017
    Publication date: May 9, 2019
    Applicant: DANMARKS TEKNISKE UNIVERSITET
    Inventors: Bjørn Gunnar Voldborg, Lasse Ebdrup Pedersen