Patents by Inventor Björn Riefke

Björn Riefke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Near infrared imaging agent
    Patent number: 7655217
    Abstract: This invention relates to an in-vivo diagnostic method based on near infrared radiation (NIR radiation) that uses water-soluble dyes and their biomolecule adducts, each having specific photophysical and pharmaco-chemical properties, as a contrast medium for fluorescence and transillumination diagnostics in the NIR range, to new dyes and pharmaceuticals containing such dyes.
    Type: Grant
    Filed: March 22, 2006
    Date of Patent: February 2, 2010
    Assignee: Institut fur Diagnosikforschung GmbH
    Inventors: Kai Licha, Björn Riefke, Wolfhard Semmler, Ulrich Speck, Christoph-Stephan Hilger
  • In-vivo diagnostic method by near infrared radiation
    Patent number: 7445767
    Abstract: This invention relates to an in-vivo diagnostic method based on near infrared radiation (NIR radiation) that uses water-soluble dyes and their biomolecule adducts, each having specific photophysical and pharmaco-chemical properties, as a contrast medium for fluorescence and transillumination diagnostics in the NIR range, to new dyes and pharmaceuticals containing such dyes.
    Type: Grant
    Filed: March 22, 2006
    Date of Patent: November 4, 2008
    Assignee: Institut fur Diagnostikforschung GmbH an der Freien Universitat Berlin
    Inventors: Kai Licha, Björn Riefke, Wolfhard Semmler, Ulrich Speck, Christoph-Stephan Hilger
  • Trimeric macrocyclic substituted benzene derivatives
    Patent number: 7208140
    Abstract: The metal complexes of general formula I in which Hal stands for bromine or iodine and A1 and A2 have different meanings, are suitable as contrast media.
    Type: Grant
    Filed: February 19, 2004
    Date of Patent: April 24, 2007
    Assignee: Schering Aktiengesellschaft
    Inventors: Heiko Schirmer, Hanns-Joachim Weinmann, Johannes Platzek, Jose Luis Martin, Juan R. Harto, Bjoern Riefke
  • In-vivo diagnostic method by means of near infrared radiation
    Patent number: 6926885
    Abstract: This invention relates to an in-vivo diagnostic method based on near infrared radiation (NIR radiation) that uses water-soluble dyes and their biomolecule adducts, each having specific photophysical and pharmaco-chemical properties, as a contrast medium for fluorescence and transillumination diagnostics in the NIR range, to new dyes and pharmaceuticals containing such dyes.
    Type: Grant
    Filed: June 26, 2002
    Date of Patent: August 9, 2005
    Assignees: Institut fur Diagnostikforschung GmbH, Freien Universitat Berlin
    Inventors: Kai Licha, Björn Riefke, Wolfhard Semmler, Ulrich Speck, Christoph-Stephan Hilger
  • Near infrared imaging agent
    Patent number: 6913743
    Abstract: This invention relates to an in-vivo diagnostic method based on near infrared radiation (NIR radiation) that uses water-soluble dyes and their biomolecule adducts, each having specific photophysical and pharmaco-chemical properties, as a contrast medium for fluorescence and transillumination diagnostics in the NIR range, to new dyes and pharmaceuticals containing such dyes.
    Type: Grant
    Filed: February 19, 2003
    Date of Patent: July 5, 2005
    Assignee: Institut fur Diagnostikforschung GmbH an der Freien Universitat Berlin
    Inventors: Kai Licha, Björn Riefke, Wolfhard Semmler, Ulrich Speck, Christoph-Stephan Hilger
  • Trimeric macrocyclic substituted benzene derivatives
    Publication number: 20040265236
    Abstract: The metal complexes of general formula I 1
    Type: Application
    Filed: February 19, 2004
    Publication date: December 30, 2004
    Inventors: Heiko Schirmer, Hanns-Joachim Weinmann, Johannes Platzek, Jose Luis Martin, Juan R. Harto, Bjoern Riefke
  • Galenical formulations
    Publication number: 20030095924
    Abstract: Abstract This invention describes galenical formulations that contain perfluoroalkyl-containing dye molecules and other perfluoroalkyl-containing substances. The new formulations are suitable as, i.a., contrast media for near-infrared diagnosis.
    Type: Application
    Filed: July 12, 2002
    Publication date: May 22, 2003
    Applicant: Schering Aktiengesellschaft
    Inventors: Kai Licha, Andreas Becker, Bjoern Riefke, Johannes Platzek
  • Perfluoro-alkyl containing dye molecules and galencial formulations
    Patent number: 6447749
    Abstract: This invention describes galenical formulations that contain perfluoroalkyl-containing dye molecules and other perfluoroalkyl-containing substances. The new formulations are suitable as, i.a., contrast media for near-infrared diagnosis.
    Type: Grant
    Filed: September 29, 2000
    Date of Patent: September 10, 2002
    Assignees: Schering Aktiengesellschaft, Institut fuer Diagnostikforschung
    Inventors: Kai Licha, Andreas Becker, Bjoern Riefke, Johannes Platzek
  • Contrast medium for near infrared diagnosis
    Patent number: 6319488
    Abstract: This invention relates to colloidal systems charged with polymethine dyes and having suitable photophysical and pharmacological properties, their use as a contrast medium in fluorescence and transillumination diagnostics in the near infrared spectral range, as well as methods for their production.
    Type: Grant
    Filed: April 9, 1998
    Date of Patent: November 20, 2001
    Assignee: Institut für Diagnostikforschung GmbH an der Freien Universität Berlin
    Inventors: Kai Licha, Björn Riefke, Werner Weitschiess, Dieter Heldmann, Violetta Sudmann
  • In-vivo diagnostic method by near infrared radiation
    Patent number: 6258340
    Abstract: This invention relates to a in-vivo diagnostic method based on near infrared ra ation (NIR radiation) that uses water-soluble dyes and their biomolecule adducts, each having specific photophysical and pharmaco-chemical properties, as a contrast medium for fluorescence and transillumination diagnostics in the NIR range, to new dyes and pharmaceuticals containing such dyes.
    Type: Grant
    Filed: March 6, 2000
    Date of Patent: July 10, 2001
    Assignees: Institut fur Diagnostikforschung GmbH, der Freien Universitat Berlin
    Inventors: Kai Licha, Björn Riefke, Wolfhard Semmler, Ulrich Speck, Christoph-Stephan Hilger