Abstract: Disclosed are chromatography systems employing a releasable coupling 100 for holding a fluid tubing to a spigot, the coupling comprising: a cylindrical inner component 110 for accepting a fluid tubing 30, said inner component including a resiliently deflectable portion 118 arranged to urge an outer surface of the tubing toward a spigot; and a cylindrical collar 130 having and internal through-aperture 132 for slideably accepting the inner component, the aperture and resilient portion having complementary surface formations which in a first position of the collar mounted to the inner component provide for said resilient deflection in use, and which in a second different position do not cause said deflection, the coupling being characterized in that the collar comprises a collar flange 134 extending outwardly away from the aperture of a size allowing manual manipulation of the collar between the first and second positions. Chromatography systems employing said couplings is disclosed also.

Abstract: Disclosed are chromatography systems employing a releasable coupling 100 for holding a fluid tubing to a spigot, the coupling comprising: a cylindrical inner component 110 for accepting a fluid tubing 30, said inner component including a resiliently deflectable portion 118 arranged to urge an outer surface of the tubing toward a spigot; and a cylindrical collar 130 having and internal through-aperture 132 for slideably accepting the inner component, the aperture and resilient portion having complementary surface formations which in a first position of the collar mounted to the inner component provide for said resilient deflection in use, and which in a second different position do not cause said deflection, the coupling being characterized in that the collar comprises a collar flange 134 extending outwardly away from the aperture of a size allowing manual manipulation of the collar between the first and second positions. Chromatography systems employing said couplings is disclosed also.

Abstract: Disclosed are chromatography systems employing a releasable coupling (100) for holding a fluid tubing to a spigot, the coupling comprising: a cylindrical inner component (110) for accepting a fluid tubing (30), said inner component including a resiliently deflectable portion (118) arranged to urge an outer surface of the tubing toward a spigot; and a cylindrical collar (130) having and internal through-aperture (132) for slideably accepting the inner component, the aperture and resilient portion having complementary surface formations which in a first position of the collar mounted to the inner component provide for said resilient deflection in use, and which in a second different position do not cause said deflection, the coupling being characterized in that the collar comprises a collar flange (134) extending outwardly away from the aperture of a size allowing manual manipulation of the collar between the first and second positions. Chromatography systems employing said couplings is disclosed also.

Abstract: Disclosed are chromatography systems employing a releasable coupling (100) for holding a fluid tubing to a spigot, the coupling comprising: a cylindrical inner component (110) for accepting a fluid tubing (30), said inner component including a resiliently deflectable portion (118) arranged to urge an outer surface of the tubing toward a spigot; and a cylindrical collar (130) having and internal through-aperture (132) for slideably accepting the inner component, the aperture and resilient portion having complementary surface formations which in a first position of the collar mounted to the inner component provide for said resilient deflection in use, and which in a second different position do not cause said deflection, the coupling being characterized in that the collar comprises a collar flange (134) extending outwardly away from the aperture of a size allowing manual manipulation of the collar between the first and second positions. Chromatography systems employing said couplings is disclosed also.

Abstract: The present invention relates to a method for manufacturing a device for holding a light guide, for use in a flow cell, with the steps of providing a light guide holder having a first end and a second end connected by a longitudinal through hole with a narrow portion at the first end having a first diameter and a wide portion at the second end having a second diameter, the first diameter being smaller than the second diameter, and the narrow portion and wide portion being connected by a tapering portion, inserting a light guide into the through hole so that a first end of the light guide extends from the first end to the second end of the light guide holder, inserting a substance into at least part of the wide portion of the through hole, Inserting a tube between the light guide and the light guide holder, and fix the light guide in relation to the holder by means of the substance. The invention also relates to a device for holding a light guide.

Abstract: The present invention relates to a method for manufacturing a device for holding a light guide, for use in a flow cell, with the steps of providing a light guide holder having a first end and a second end connected by a longitudinal through hole with a narrow portion at the first end having a first diameter and a wide portion at the second end having a second diameter, the first diameter being smaller than the second diameter, and the narrow portion and wide portion being connected by a tapering portion, inserting a light guide into the through hole so that a first end of the light guide extends from the first end to the second end of the light guide holder,inserting a substance into at least part of the wide portion of the through hole,Inserting a tube between the light guide and the light guide holder, and fix the light guide in relation to the holder by means of the substance. The invention also relates to a device for holding a light guide.

Abstract: A sanitary piston head with a body, said piston head having a fluid-contact end and a drive end and comprising a resilient sealing skirt arranged to provide sealing abutment against the inner wall of a cylinder when said piston head is inserted in said cylinder, wherein the resilient sealing skirt is biased in the sealing direction by a radially biasing element.

Abstract: A pinch valve is adapted to hold at least one flexible tube in a tube holding room (7) and comprises a plunger (13) adapted to protrude into the tube holding room and pinch the tube against an opposite side wall (11) thereof. The plunger (13) is controllable to be positioned in at least two different positions, an open position where the tube in the tube holding room (7) is not pinched, and a pinching position where the tube is pinched between the plunger (13) and the opposing wall (11). The pinch valve further comprises a tube retaining means (19) adapted to prevent the tube from escaping from the tube holding room (7), especially when the plunger (13) is in the open position, and which can be pivoted into at least two different positions, a non locking position used during insertion of a tube into the tube holding room (7), and a locking position for retaining a tube inside the tube holding room (7) even when the plunger is in an open position.

Abstract: A separation device adapted for separation of a wanted end product from a sample by centrifugation. According to the invention the device comprises: a first, a second and a third compartment; a first fluid connection between the first and second compartments, arranged to be opened and closed by first closing means; a second fluid connection between the second and the third compartments, arranged to be opened and closed by second closing means. The separation device is adapted to be subjected to centrifugation after having been filled with a first density gradient medium in the first compartment, sample in the third compartment and a second density gradient medium or sample in the second compartment, whereby after centrifugation the wanted end product will settle in the second compartment and the first fluid connection and the second fluid connection will be closed by the first closing means and the second closing means respectively.

Abstract: A pinch valve is adapted to hold at least one flexible tube in a tube holding room (7) and comprises a plunger (13) adapted to protrude into the tube holding room and pinch the tube against an opposite side wall (11) thereof The plunger (13) is controllable to be positioned in at least two different positions, an open position where the tube in the tube holding room (7) is not pinched, and a pinching position where the tube is pinched between the plunger (13) and the opposing wall (11). The pinch valve further comprises a tube retaining means (19) adapted to prevent the tube from escaping from the tube holding room (7), especially when the plunger (13) is in the open position, and which can be pivoted into at least two different positions, a non locking position used during insertion of a tube into the tube holding room (7), and a locking position for retaining a tube inside the tube holding room (7) even when the plunger is in an open position.