Abstract: A trailer hitch for releasably connecting a trailer to a bicycle includes a body and a safety device. The body is configured to attach the trailer to the trailer hitch and configured to mount to the bicycle. The safety device is configured to provide a redundant connection of the trailer to the bicycle. The safety device includes a first securing element configured to connect the body of the trailer hitch to a frame of the bicycle. The first securing element is configured to remain attached to the bicycle frame independently of an attachment of the trailer to the trailer hitch.

Abstract: A trailer hitch for releasably connecting a trailer to a bicycle includes a body and a safety device. The body is configured to attach the trailer to the trailer hitch and configured to mount to the bicycle. The safety device is configured to provide a redundant connection of the trailer to the bicycle. The safety device includes a first securing element configured to connect the body of the trailer hitch to a frame of the bicycle. The first securing element is configured to remain attached to the bicycle frame independently of an attachment of the trailer to the trailer hitch.

Abstract: Resource teaming optimization for resource planning is provided by identifying a set of tasks, wherein each task of the set of tasks includes a plurality of subtasks that includes an initial subtask starting at a given state and a final subtask returning to the given state; identifying resource requirements for each subtasks of the plurality of subtasks; dividing a set of resources into a plurality of candidate slices to meet resource requirements for the plurality of subtasks; forming a plurality of combinations from the plurality of candidate slices to satisfy the resource requirements; identifying a given combination from the plurality of combinations having a highest teaming metric across the set of tasks; and assigning the given combination for the set of tasks.

Abstract: A process and a system for forming of a workpiece using a press including a pressure generator, a forming tool, and an at least in part elastically deformable element, are disclosed. At least one of the workpiece or the forming tool is heated, and the workpiece is formed using the press so as to obtain a formed workpiece. The heating of at least one of the workpiece or the forming tool is such that the temperature of the at least one of the workpiece or the forming tool during the forming of the workpiece by way of forming pressure generated by the pressure generator is higher than the ambient temperature.

Abstract: A method of processing exchange system trading data is disclosed. In one embodiment, the method comprises receiving an order data message from a matching engine of an automated exchange. The order data message has first data format and it also comprises identification information associated with a trading entity. The received data message is then converted into a new data message of a new data format, which is different from the data format of the received order data message. Also, the trading entity from which the received order data message is originating is identified. Subsequently, the new data message having the new data format can be transmitted to a plurality of client devices associated with the identified trading entity. This may allow for all, or at least a majority of client devices, of the identified trading entity to get an overview of the total order activity of the identified trading entity.

Abstract: A method of processing exchange system trading data is disclosed. In one embodiment, the method comprises receiving an order data message from a matching engine of an automated exchange. The order data message has first data format and it also comprises identification information associated with a trading entity. The received data message is then converted into a new data message of a new data format, which is different from the data format of the received order data message. Also, the trading entity from which the received order data message is originating is identified. Subsequently, the new data message having the new data format can be transmitted to a plurality of client devices associated with the identified trading entity. This may allow for all, or at least a majority of client devices, of the identified trading entity to get an overview of the total order activity of the identified trading entity.

Abstract: A process and a system for forming of a workpiece using a press including a pressure generator, a forming tool, and an at least in part elastically deformable element, are disclosed. At least one of the workpiece or the forming tool is heated, and the workpiece is formed using the press so as to obtain a formed workpiece. The heating of at least one of the workpiece or the forming tool is such that the temperature of the at least one of the workpiece or the forming tool during the forming of the workpiece by way of forming pressure generated by the pressure generator is higher than the ambient temperature.

Abstract: A method of processing exchange system trading data is disclosed. In one embodiment, the method comprises receiving an order data message from a matching engine of an automated exchange. The order data message has first data format and it also comprises identification information associated with a trading entity. The received data message is then converted into a new data message of a new data format, which is different from the data format of the received order data message. Also, the trading entity from which the received order data message is originating is identified. Subsequently, the new data message having the new data format can be transmitted to a plurality of client devices associated with the identified trading entity. This may allow for all, or at least a majority of client devices, of the identified trading entity to get an overview of the total order activity of the identified trading entity.

Abstract: The present invention relates a pharmaceutical composition comprising an EGFR inhibitor and methylene-tetrahydrofolate, tetrahydrofolate or methyl-tetrahydrofolate, for use in the treatment of cancer. The methylene-tetrahydrofolate, tetrahydrofolate or methyl-tetrahydrofolate enhances the anticancer efficacy of the EGFR inhibitor. The cancers that may be treated include breast cancer, gastric cancer, gastrointestinal cancer, gall bladder cancer, bile duct cancer, colon cancer, rectal cancer, liver cancer, pancreatic cancer, head and neck cancer, esophageal cancer, mesothelioma cancer, lung cancer including non-small-cell lung cancer, ovarian cancer, endometrial cancer, cervical cancer, peripheral T-cell lymphoma (PTCL), melanoma, brain tumors, adenocarcinoma, esophageal cancer, and osteosarcoma.

Abstract: The present invention relates to methylene-tetrahydrofolate for use in the treatment of cancer, based on its intrinsic antitumor activity. The cancers that may be treated include breast cancer, gastric cancer, gastrointestinal cancer, gall bladder cancer, bile duct cancer, colon cancer, rectal cancer, liver cancer, pancreatic cancer, head and neck cancer, esophageal cancer, mesothelioma cancer, lung cancer including non-small-cell lung cancer, ovarian cancer, endometrial cancer, cervical cancer, peripheral cell lymphoma (PTCL), melanoma, brain tumors, adenocarcinoma, esophageal cancer, and osteosarcoma.

Abstract: The present invention relates a pharmaceutical composition comprising an EGFR inhibitor and methylene-tetrahydrofolate, tetrahydrofolate or methyl-tetrahydrofolate, for use in the treatment of cancer. The methylene-tetrahydrofolate, tetrahydrofolate or methyl-tetrahydrofolate enhances the anticancer efficacy of the EGFR inhibitor.

Abstract: A method of processing exchange system trading data is disclosed. In one embodiment, the method comprises receiving an order data message from a matching engine of an automated exchange. The order data message has first data format and it also comprises identification information associated with a trading entity. The received data message is then converted into a new data message of a new data format, which is different from the data format of the received order data message. Also, the trading entity from which the received order data message is originating is identified. Subsequently, the new data message having the new data format can be transmitted to a plurality of client devices associated with the identified trading entity. This may allow for all, or at least a majority of client devices, of the identified trading entity to get an overview of the total order activity of the identified trading entity.

Abstract: The present invention describes a Coronary artery disease (CAD) susceptibility gene and the use of this gene in the development of novel therapies to treat CAD and in the diagnosis of susceptibility to CAD.