Patents by Inventor Bjorn Hock

Bjorn Hock has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROTEINS THAT DECOUPLE T CELL-MEDIATED TUMOR CYTOTOXICITY FROM RELEASE OF PRO-INFLAMMATORY CYTOKINES
    Publication number: 20240343800
    Abstract: This disclosure relates generally to proteins target tumor cell killing comprising: a polypeptide or complex of two or more polypeptides that specifically binds ROR1, and a polypeptide or complex of two or more polypeptides that specifically binds CD3. In some embodiments, the present application provides antibodies that specifically bind ROR1. In some embodiments the application also provides therapeutic methods for using such proteins in the treatment of a cancer.
    Type: Application
    Filed: February 8, 2024
    Publication date: October 17, 2024
    Inventors: Brian Rabinovich, Jessica Dawson, Xueyuan Zhou, Stefan Becker, Yves Fomekong Nanfack, Christian Schroeter, Lars Toleikis, Achim Doerner, Bjorn Hock
  • Human survivin interacting protein 1 (SIP-1)
    Patent number: 7166701
    Abstract: Survivin Interacting Protein 1 and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing SIP-1 polypeptides and polynucleotides in diagnostic assays.
    Type: Grant
    Filed: March 21, 2001
    Date of Patent: January 23, 2007
    Assignee: Merck Patent GmbH
    Inventors: Bernd Hentsch, Klaus Dücker, Björn Hock
  • Histidine phosphatase interacting protein with 120kd
    Publication number: 20050070002
    Abstract: PHPIP-120 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed, also disclosed are methods for utilizing PHPIP-120 polypeptides and polynucleotides in diagnostic assays.
    Type: Application
    Filed: January 25, 2002
    Publication date: March 31, 2005
    Applicant: Merck Patent GmbH
    Inventors: Bjorn Hock, Klaus Ducker, Roland Kellner
  • Human survivin interacting protein 1 (sip-1)
    Publication number: 20040254346
    Abstract: Survivin Interacting Protein 1 and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing SIP-1 polypeptides and polynucleotides in diagnostic assays.
    Type: Application
    Filed: September 24, 2002
    Publication date: December 16, 2004
    Inventors: Bernd Hentsch, Klaus Ducker, Bjorn Hock
  • Acute neuronal induced calcium binding protein type 1 ligand
    Publication number: 20030148446
    Abstract: ANIC-BP-1 ligand polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing ANIC-BP-1 ligand polypeptides and polynucleotides in diagnostic assays.
    Type: Application
    Filed: September 19, 2002
    Publication date: August 7, 2003
    Inventors: Izaak Den Daas, Klaus Ducker, Bjorn Hock
  • Gtpase-activating protein 1
    Publication number: 20030096282
    Abstract: New GTPase-Activating Protein 1 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing New GTPase-Activating Protein 1 polypeptides and polynucleotides in diagnostic assays.
    Type: Application
    Filed: October 30, 2002
    Publication date: May 22, 2003
    Inventors: Christian Sirrenberg, Bjorn Hock, Jorg Dietrich Hoheisel, Marcus Frohme