Abstract: Compounds having the structure of Formula (I): and pharmaceutically acceptable salts thereof, wherein X1, R1, R2, R3, R4, R5 and R6 are as defined in the specification; pharmaceutical compositions comprising such compounds and salts; use of such compounds and salts to treat or prevent Prolyl endopeptidase fibroblast activation protein (FAP)-mediated conditions; kits comprising such compounds and salts; and methods for manufacturing such compounds and salts.

Abstract: The invention relates to a method of operating an apparatus for applying drinking straws to packaging containers. The method comprises the step of moving a drinking straw carrier from an application position to the leaving position, in a packaging container moving direction, maintaining a velocity in that direction being equal to a constant velocity of a first conveyor. The invention also relates to an apparatus being operated according to the method.

Abstract: A connector, an associated dynamic testing system and method for testing rock bolts or rock anchors in situ. The connector is attached to a rock bolt/anchor and supports a hanging load via a shaft. The connector has a body of two halves retaining upper first and lower second connectors having respective curved surfaces. Each of the two halves has a curved inner surface allowing limited relative rotational movement of the first and second connectors relative to the two halves when a load is applied. A load cell and accelerometer register the load applied to the rock bolt/anchor through the connector and any resulting movement of the rock bolt/anchor.

Abstract: The invention relates to a method of operating an apparatus for applying drinking straws to packaging containers. The method comprises the step of moving a drinking straw carrier from an application position to the leaving position, in a packaging container moving direction, maintaining a velocity in that direction being equal to a constant velocity of a first conveyor. The invention also relates to an apparatus being operated according to the method.

Abstract: A forming device and method for use in a packaging machine of the type where packages are produced from a tube. The forming device comprises two opposing sealing elements between which the tube is arranged to be flat-laid and squeezed to heat the thermoplastic and obtain a first transverse seal of the tube. It further comprises two volume control elements. The forming device is characterized in that it is arranged to displace the first transverse seal off-center in relation a longitudinal axis of the first portion of the tube in a displacement direction essentially perpendicular to the first transverse seal to enable later shaping of a corresponding final package with a wall arranged with a predetermined angle of inclination in relation to the displacement direction. The invention also relates to a machine, a process and a packaging laminate.

Abstract: An earthmoving equipment bucket corner has a first portion, a second portion and an intermediate portion between the first and second portions, all in different planes to one another. A boss or lug is provided on the leading edge of the intermediate portion. The intermediate portion is angled relative to both the first and second portions, which alleviates the load stresses otherwise created in a traditional 90° corner. The first portion has a wall with a taper or bevel towards a forward edge. The second portion has a wall with a leading flared wall portion that widens the corner at the front. The intermediate portion is preferably at an included angle of around 120° to 170° with respect to the respective walls of the first and second portions.

Abstract: A connection assembly for mounting a ground engaging tool to earthmoving equipment includes a body into which is received a resilient member, a force applying member, a locking member with an O-ring seal to be received in an annular channel around the locking member, a locking member stop received in a hole in the locking member, and a body stop to be fitted into an aperture under the body. The locking member stop prevents the force applying member from rotating within the body when the bolt is rotated and advances the piston by threaded engagement.

Abstract: A connector, an associated dynamic testing system and method for testing rock bolts or rock anchors in situ. The connector is attached to a rock bolt/anchor and supports a hanging load via a shaft. The connector has a body of two halves retaining upper first and lower second connectors having respective curved surfaces. Each of the two halves has a curved inner surface allowing limited relative rotational movement of the first and second connectors relative to the two halves when a load is applied. A load cell and accelerometer register the load applied to the rock bolt/anchor through the connector and any resulting movement of the rock bolt/anchor.

Abstract: A connection assembly for mounting a ground engaging tool to earthmoving equipment includes a body into which is received a resilient means, a force applying member, a locking member with an O-ring seal to be received in an annular channel around the locking member, a locking member stop received in a hole in the locking member, and a body stop to be fitted into an aperture under the body. The locking member stop prevents the force applying member from rotating within the body when the bolt is rotated and advances the piston by threaded engagement.

Abstract: An earthmoving equipment bucket corner has a first portion, a second portion and an intermediate portion between the first and second portions, all in different planes to one another. A boss or lug is provided on the leading edge of the intermediate portion. The intermediate portion is angled relative to both the first and second portions, which alleviates the load stresses otherwise created in a traditional 90° corner. The first portion has a wall with a taper or bevel towards a forward edge. The second portion has a wall with a leading flared wall portion that widens the corner at the front. The intermediate portion is preferably at an included angle of around 120° to 170° with respect to the respective walls of the first and second portions.

Abstract: A forming device and method for use in a packaging machine of the type where packages are produced from a tube. The forming device comprises two opposing sealing elements between which the tube is arranged to be flat-laid and squeezed to heat the thermoplastic and obtain a first transverse seal of the tube. It further comprises two volume control elements. The forming device is characterized in that it is arranged to displace the first transverse seal off-center in relation a longitudinal axis of the first portion of the tube in a displacement direction essentially perpendicular to the first transverse seal to enable later shaping of a corresponding final package with a wall arranged with a predetermined angle of inclination in relation to the displacement direction. The invention also relates to a machine, a process and a packaging laminate.

Abstract: A forming device and method for use in a packaging machine of the type where packages are produced from a tube. The forming device comprises two opposing sealing elements between which the tube is arranged to be flat-laid and squeezed to heat the thermoplastic and obtain a first transverse seal of the tube. It further comprises two volume control elements. The forming device is arranged to displace the first transverse seal off-center in relation a longitudinal axis of the first portion of the tube in a displacement direction essentially perpendicular to the first transverse seal to enable later shaping of a corresponding final package with a wall arranged with a predetermined angle of inclination in relation to the displacement direction. Also disclosed is a machine, a process and a packaging laminate.

Abstract: A forming device and method for use in a packaging machine of the type where packages are produced from a tube. The forming device comprises two opposing sealing elements between which the tube is arranged to be flat-laid and squeezed to heat the thermoplastic and obtain a first transverse seal of the tube. It further comprises two volume control elements. The forming device is arranged to displace the first transverse seal off-center in relation a longitudinal axis of the first portion of the tube in a displacement direction essentially perpendicular to the first transverse seal to enable later shaping of a corresponding final package with a wall arranged with a predetermined angle of inclination in relation to the displacement direction. Also disclosed is a machine, a process and a packaging laminate.

Abstract: The present invention relates to an arrangement in a wheel lifting mechanism designed to lift at least one wheel (1) running on an underlying surface so that it is capable of negotiating an obstacle (h) rising above the underlying surface. The arrangement comprises an element (7) which is formed with a contour convexly curved towards the underlying surface and is moveably supported in relation to the axle of the wheel (1). The said element is designed, when the contour of the element (7) engages with the obstacle (h), to bring about the said lifting of the wheel (7) as the element (7) is rotated about its point of engagement with the obstacle (h). The arrangement further comprises a chassis (4), to which the wheel axle is firmly connected.

Abstract: The present invention relates to an arrangement in a wheel lifting mechanism designed to lift at least one wheel (1) running on an underlying surface so that it is capable of negotiating an obstacle (h) rising above the underlying surface. The arrangement comprises an element (7) which is formed with a contour convexly curved towards the underlying surface and is moveably supported in relation to the axle of the wheel (1). The said element is designed, when the contour of the element (7) engages with the obstacle (h), to bring about the said lifting of the wheel (7) as the element (7) is rotated about its point of engagement with the obstacle (h). The arrangement further comprises a chassis (4), to which the wheel axle is firmly connected.

Abstract: A new and improved way of continuously cooking fiber material, wherein temperatures and alkaline levels are controlled to be maintained within specific levels in different zones of the digesting process in order to optimize chemical consumption and heat-economy and at the same time achieve very good pulp properties. The digesting process includes a top separator that separates the transport liquid from the fiber material and permits the fiber material to be exposed to the cooking liquid.

Abstract: A new and improved way of continuously cooking fiber material, wherein temperatures and alkaline levels are controlled to be maintained within specific levels in different zones of the digesting process in order to optimize chemical consumption and heat-economy and at the same time achieve very good pulp properties. The digesting process includes a top separator that separates the transport liquid from the fiber material and permits the fiber material to be exposed to the cooking liquid.

Abstract: In a washing apparatus for washing cellulose pup, comprising a vertical, column-shaped washing vessel (2), and a screen unit (7) which is movable in the washing vessel, during a screening phase, at a first speed, from an upper position to a lower position, and, during a return movement, at a substantially higher speed, from the lower position to the upper position, there is a float body (30) which exerts a buoyancy force on the screen unit.

Abstract: A new and improved way of continuously cooking fiber material, wherein temperatures and alkaline levels are controlled to be maintained within specific levels in different zones of the digesting process in order to optimize chemical consumption and heat-economy and at the same time achieve very good pulp properties. The digesting process includes a top separator that separates the transport liquid from the fiber material and permits the fiber material to be exposed to the cooking liquid.

Abstract: The invention relates to a diffuser having a substantially cylindrical container through which cellulose pulp is arranged to be transported, nozzle arms for delivering a fluid to the pulp, a scraper arm with scrapers spaced apart from the nozzle arms, and concentrically disposed screen surfaces and screen arms disposed on and connected to the screen surfaces for withdrawal of the fluid. The screen arms are provided, at their outer ends, with fixed, non-pivotal withdrawal pipes that are slidably controlled and are connected in sealing arrangement to filtrate outlets. The screen arms have interior withdrawal areas with increasing cross-sectional areas as the screen arms extend toward the withdrawal pipes. The screen arms also include long and short plugs for controlling the filtrate flow capacity of the diffuser.