Abstract: Provided, among other things, is an isolated nucleic acid encoding a GABA-gated chloride channel having: (a) a nucleic acid including a sequence encoding a protein sequence of SEQ ID NO: 3, SEQ ID NO: 6 or SEQ ID NO: 8, or a sequence having at least about 85% sequence identity with SEQ ID NO: 3, SEQ ID NO: 6 or SEQ ID NO: 8, or (b) a nucleic acid that hybridizes with a nucleic acid encoding a protein sequence of SEQ ID NO: 3, SEQ ID NO: 6 or SEQ ID NO: 8 or the complementary sequence to SEQ ID NO: 3, SEQ ID NO: 6 or SEQ ID NO: 8, under stringent conditions; or (c) a nucleic acid that hybridizes with a nucleic acid having a sequence of SEQ ID NO: 1, SEQ ID NO: 4 or SEQ ID NO: 7 or the complementary sequence to SEQ ID NO: 1, SEQ ID NO: 4 or SEQ ID NO: 7, under stringent conditions; or (d) a nucleic acid has at least about 85% sequence identity with the coding region of SEQ ID NO: 1, SEQ ID NO: 4 or SEQ ID NO: 7.

Abstract: Disclosed is a method and a pharmaceutical composition for killing mammalian tumor cells by subjecting the cells to light in the presence of a light-activatable tetrapyrrole, in which the improvement comprises treating the cells with a compound which inhibits the enzymatic conversion of protoporphyrinogen to protoporphyrin IX by protoporphyrinogen oxidase in the cells thereby causing a buildup of protoporphyrin IX in the cells. Also disclosed is a method for the production of protoporphyrin IX which comprises growing eukaryotic microalgae in the presence of a protoporphyrinogen oxidase inhibitor.

Abstract: The present application discloses herbicidal substituted-phenyl-1,2,4-Triazol-5(1H)-thiones and -ones, herbicidal compositions containing these compounds, methods of preparing them, and methods for controlling undesired plant growth by preemergence and/or postemergence application of the herbicidal compositions to the locus where control is desired. The herbicidal compounds are compounds of the formula ##STR1## wherein: Ar is selected from ##STR2## R is selected from haloalkyl; R.sup.1 is selected from alkyl;R.sup.2 is selected from hydrogen, halogen, alkyl, haloalkoxy, haloalkyl, alkoxy, alkynyl, alkylthio, nitro, amino and cyano;R.sup.3 is selected from hydrogen, halogen, alkyl, alkoxy, alkynyl, nitro, amino, mono- or disubstituted amino, cyano and hydroxy;R.sup.3 is selected from hydrogen, halogen, alkyl, alkoxy, alkynyl, nitro, amino, mono- or disubstituted amino, cyano and hydroxy;R.sup.

Abstract: Disclosed is a method and a pharmaceutical composition for killing mammalian tumor cells by subjecting said cells to light in the presence of a light-activatable tetrapyrrole, in which the improvement comprises treating said cells with a compound which inhibits the enzymatic conversion of protoporphyrinogen to protoporphyrin IX by protoporphyrinogen oxidase in said cells thereby causing a buildup of protoporphyrin IX in said cells. Also disclosed is a method for the production of protoporphyrin IX which comprises growing eukaryotic microalgae in the presence of a protoporphyrinogen oxidase inhibitor.

Abstract: The present application discloses herbicidal substituted-phenyl-1,2,4-Triazole-5(1H)-thiones and -ones, herbicidal compositions containing these compounds, methods of preparing them, and methods for controlling undesired plant growth by preemrgence and/or postemergence application of the herbicidal compositions to the locus where control is desired. The herbicidal compounds are compounds of the formula ##STR1## wherein Ar is selected from ##STR2## R is selected from haloalkyl; R.sup.1 is selected from alkyl;R.sup.2 is selected from hydrogen, halogen, alkyl haloalkoxy, haloalkyl, alkoxy, alkynyl, alkylthio, nitro, amino and cyano;R.sup.3 is selected from hydrogen, halogen, alkyl, alkoxy, alkynyl, nitro, amino, mono- or disubstituted amino, cyano and hydroxyR.sup.3 is selected from hydrogen, halogen, alkyl, alkoxy, alkynyl, nitro, amino, mono- or disubstituted amino, cyano and hydroxy;R.sup.