Patents by Inventor Blaine G. Doletski
Blaine G. Doletski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9180217Abstract: A system, device and method for sterilizing or decontaminating an object that by exposing the object to a sterilant gas comprised of one or more oxides of nitrogen, such as NO, NO2, NO3, N2O3, N2O4, N2O5, N2O and mixtures thereof. The source of the sterilant gas can be generated from a sterilant gas-generating composition or provided by a source of the sterilant gas.Type: GrantFiled: August 18, 2014Date of Patent: November 10, 2015Assignee: NOXILIZER, INC.Inventors: Ernst V. Arnold, Blaine G. Doletski, Thomas M. Dunn, Robert E. Raulli, Edward P. Mueller, Karen R. Benedek, Marie-Louise Murville
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Publication number: 20150273095Abstract: A system, device and method for sterilizing or decontaminating an object that by exposing the object to a sterilant gas comprised of one or more oxides of nitrogen, such as NO, NO2, NO3, N2O3, N2O4, N2O5, N2O and mixtures thereof. The source of the sterilant gas can be generated from a sterilant gas-generating composition or provided by a source of the sterilant gas.Type: ApplicationFiled: August 18, 2014Publication date: October 1, 2015Inventors: Ernst V. ARNOLD, Blaine G. DOLETSKI, Thomas M. DUNN, Robert E. RAULLI, Edward P. MUELLER, Karen R. BENEDEK, Marie-Louise MURVILLE
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Publication number: 20150110670Abstract: A system and method for decontamination of isolation enclosures includes a recirculating isolator configured to allow injection of a sterilant gas into the isolator. Levels of humidity and sterilant gas are selected to avoid condensation of either within the isolator. In an embodiment, a positive pressure is maintained throughout the sterilization process.Type: ApplicationFiled: August 17, 2012Publication date: April 23, 2015Inventors: David Opie, Evan M. Goulet, Blaine G. Doletski, William E. Waters
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Patent number: 8894985Abstract: This invention relates to compositions comprising carbon-based diazeniumdiolates attached to hydrophobic polymers that releases nitric oxide (NO). The carbon-based diazeniumdiolated polymers release NO spontaneously under physiological conditions without subsequence nitrosamine formation. The present invention also relates to methods of preparing the carbon-based diazeniumdiolated polymers, compositions comprising such polymers, methods of using such compositions, and devices employing such polymer compositions.Type: GrantFiled: November 5, 2010Date of Patent: November 25, 2014Assignee: Amulet Pharmaceuticals, Inc.Inventors: Ernst V. Arnold, Blaine G. Doletski, Robert E. Raulli
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Publication number: 20140301895Abstract: A sterilization system includes a plurality of modular gas impermeable chambers separable by doors movable between an open position in which gas may flow freely between the adjacent chambers and a closed position in which gas flow between the adjacent chambers is prevented. A conveyor system carries objects between the chambers. Sterilant gas is controllably deliverable to at least one of the chambers. Objects are conveyed between the chambers to execute a sterilization operation.Type: ApplicationFiled: August 3, 2012Publication date: October 9, 2014Applicant: Noxilizer Inc.Inventors: David B. Opie, Evan M. Goulet, Blaine G. Doletski, William E. Waters
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Patent number: 8808622Abstract: A system, device and method for sterilizing or decontaminating an object that by exposing the object to a sterilant gas comprised of one or more oxides of nitrogen, such as NO, NO2, NO3, N2O3, N2O4, N2O5, N2O and mixtures thereof. The source of the sterilant gas can be generated from a sterilant gas-generating composition or provided by a source of the sterilant gas.Type: GrantFiled: July 29, 2011Date of Patent: August 19, 2014Assignee: Noxilizer, Inc.Inventors: Ernst V. Arnold, Blaine G. Doletski, Thomas M. Dunn, Robert E. Raulli, Edward P. Mueller, Karen R. Benedek, Marie-Louise Murville
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Patent number: 8101589Abstract: This invention relates to compositions comprising carbon-based diazeniumdiolates that release nitric oxide (NO). The carbon-based diazeniumdiolated molecules release NO spontaneously under physiological conditions without subsequent nitrosamine formation. The present invention also relates to methods of preparing the carbon-based diazeniumdiolated molecules, compositions comprising such molecules, methods of using such compositions, and devices employing such molecule compositions.Type: GrantFiled: July 2, 2009Date of Patent: January 24, 2012Assignee: Noxilizer, Inc.Inventors: Ernst V. Arnold, Blaine G. Doletski, Robert E. Raulli
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Publication number: 20110318225Abstract: A system, device and method for sterilizing or decontaminating an object that by exposing the object to a sterilant gas comprised of one or more oxides of nitrogen, such as NO, NO2, NO3, N2O3, N2O4, N2O5, N2O and mixtures thereof. The source of the sterilant gas can be generated from a sterilant gas-generating composition or provided by a source of the sterilant gas.Type: ApplicationFiled: July 29, 2011Publication date: December 29, 2011Applicant: NOXILIZER, INC.Inventors: Ernst V. ARNOLD, Blaine G. Doletski, Thomas M. Dunn, Robert E. Raulli, Edward P. Mueller, Karen R. Benedek, Marie-Louise Murville
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Patent number: 8017074Abstract: A system, device and method for sterilizing or decontaminating an object that by exposing the object to a sterilant gas comprised of one or more oxides of nitrogen, such as NO, NO2, NO3, N2O3, N2O4, N2O5, N2O and mixtures thereof. The source of the sterilant gas can be generated from a sterilant gas-generating composition or provided by a source of the sterilant gas.Type: GrantFiled: June 30, 2006Date of Patent: September 13, 2011Assignee: Noxilizer, Inc.Inventors: Ernst V. Arnold, Blaine G. Doletski, Thomas M. Dunn, Robert E. Raulli, Edward P. Mueller, Karen R. Benedek, Marie-Louise Murville
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Publication number: 20110059036Abstract: This invention relates to compositions comprising carbon-based diazeniumdiolates attached to hydrophobic polymers that releases nitric oxide (NO). The carbon-based diazeniumdiolated polymers release NO spontaneously under physiological conditions without subsequence nitrosamine formation. The present invention also relates to methods of preparing the carbon-based diazeniumdiolated polymers, compositions comprising such polymers, methods of using such compositions, and devices employing such polymer compositions.Type: ApplicationFiled: November 5, 2010Publication date: March 10, 2011Inventors: Ernst V. ARNOLD, Blaine G. Doletski, Robert E. Raulli
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Patent number: 7829553Abstract: This invention relates to compositions comprising carbon-based diazeniumdiolates attached to hydrophobic polymers that releases nitric oxide (NO). The carbon-based diazeniumdiolated polymers release NO spontaneously under physiological conditions without subsequent nitrosamine formation. The present invention also relates to methods of preparing the carbon-based diazeniumdiolated polymers, compositions comprising such polymers, methods of using such compositions, and devices employing such polymer compositions.Type: GrantFiled: January 6, 2005Date of Patent: November 9, 2010Assignee: Amulet Pharmaceuticals, Inc.Inventors: Ernst V. Arnold, Blaine G. Doletski, Robert E. Raulli
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Publication number: 20090270509Abstract: This invention relates to compositions comprising carbon-based diazeniumdiolates that release nitric oxide (NO). The carbon-based diazeniumdiolated molecules release NO spontaneously under physiological conditions without subsequent nitrosamine formation. The present invention also relates to methods of preparing the carbon-based diazeniumdiolated molecules, compositions comprising such molecules, methods of using such compositions, and devices employing such molecule compositions.Type: ApplicationFiled: July 2, 2009Publication date: October 29, 2009Applicant: Noxilizer, Inc.Inventors: Ernst V. Arnold, Blaine G. Doletski, Robert E. Raulli
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Patent number: 7569559Abstract: This invention relates to compositions comprising carbon-based diazeniumdiolates that release nitric oxide (NO). The carbon-based diazeniumdiolated molecules release NO spontaneously under physiological conditions without subsequent nitrosamine formation. The present invention also relates to methods of preparing the carbon-based diazeniumdiolated molecules, compositions comprising such molecules, methods of using such compositions, and devices employing such molecule compositions.Type: GrantFiled: February 9, 2005Date of Patent: August 4, 2009Assignee: Noxilizer, Inc.Inventors: Ernst V. Arnold, Blaine G. Doletski, Robert E. Raulli