Patents by Inventor Blair Madison

Blair Madison has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR DELIVERY OF NUCLEIC ACIDS
    Publication number: 20240189446
    Abstract: The present disclosure provides compositions and methods for the genetic modification of cells, including, but not limited to, hepatocytes. The compositions and methods can comprise lipid nanoparticles, wherein the lipid nanoparticles comprise at least one bioreducible ionizable cationic lipid, at least one structural lipid, at least one phospholipid and at least one PEGylated lipid.
    Type: Application
    Filed: February 23, 2022
    Publication date: June 13, 2024
    Inventors: Joshua RYCHAK, Sean ESSEX, Matthew BUTCHER, Peter GRIFFIN, Blair MADISON, Renata MARTIN, Neha PARAYATH, Michael J. BENNETT, Khalid A. HAJJ, Oscar ALVAREZ, Dan J. SMITH
  • HYPERACTIVE PIGGYBAC TRANSPOSASES
    Publication number: 20240150734
    Abstract: The present invention provides PiggyBac transposase proteins, nucleic acids encoding the same, compositions comprising the same, kits comprising the same, non-human transgenic animals comprising the same, and methods of using the same.
    Type: Application
    Filed: October 31, 2022
    Publication date: May 9, 2024
    Inventors: Eric M. OSTERTAG, Blair MADISON
  • FOLDABLE COMPUTING DEVICE SPINE COVER PLATE
    Publication number: 20240069605
    Abstract: A computing device includes a first display-supporting frame rotatably coupled to a second display-supporting frame along a hinge axis via a hinge assembly comprising a central spine extending parallel to the hinge axis. A flexible display is supported by the first display-supporting frame and the second display-supporting frame. A spine cover plate extends over the central spine and is moveably coupled to the hinge assembly for translation relative to the central spine as the first display-supporting frame is rotated relative to the second display-supporting frame.
    Type: Application
    Filed: December 14, 2022
    Publication date: February 29, 2024
    Applicant: Microsoft Technology Licensing, LLC
    Inventors: Tung Yuen LAU, Blair Madison KENT, Amit KAISTHA, Eric Paul WITT
  • Hyperactive piggybac transposases
    Patent number: 11485959
    Abstract: The present invention provides PiggyBac transposase proteins, nucleic acids encoding the same, compositions comprising the same, kits comprising the same, non-human transgenic animals comprising the same, and methods of using the same.
    Type: Grant
    Filed: March 19, 2019
    Date of Patent: November 1, 2022
    Assignee: Poseida Therapeutics, Inc.
    Inventors: Eric M. Ostertag, Blair Madison
  • HYPERACTIVE PIGGYBAC TRANSPOSASES
    Publication number: 20200087635
    Abstract: The present invention provides PiggyBac transposase proteins, nucleic acids encoding the same, compositions comprising the same, kits comprising the same, non-human transgenic animals comprising the same, and methods of using the same.
    Type: Application
    Filed: March 19, 2019
    Publication date: March 19, 2020
    Inventors: Eric M. OSTERTAG, Blair MADISON
  • Hyperactive PiggyBac transposases
    Patent number: 10287559
    Abstract: The present invention provides PiggyBac transposase proteins, nucleic acids encoding the same, compositions comprising the same, kits comprising the same, non-human transgenic animals comprising the same, and methods of using the same.
    Type: Grant
    Filed: July 28, 2016
    Date of Patent: May 14, 2019
    Assignee: Poseida Therapeutics, Inc.
    Inventors: Eric Ostertag, Blair Madison
  • Hyperactive piggybac transposases
    Patent number: 10131885
    Abstract: The present invention provides PiggyBac transposase proteins, nucleic acids encoding the same, compositions comprising the same, kits comprising the same, non-human transgenic animals comprising the same, and methods of using the same.
    Type: Grant
    Filed: December 20, 2017
    Date of Patent: November 20, 2018
    Assignee: Poseida Therapeutics, Inc.
    Inventors: Eric Ostertag, Blair Madison
  • HYPERACTIVE PIGGYBAC TRANSPOSASES
    Publication number: 20180142219
    Abstract: The present invention provides PiggyBac transposase proteins, nucleic acids encoding the same, compositions comprising the same, kits comprising the same, non-human transgenic animals comprising the same, and methods of using the same.
    Type: Application
    Filed: December 20, 2017
    Publication date: May 24, 2018
    Inventors: Eric OSTERTAG, Blair MADISON
  • Hyperactive Piggybac Transposases
    Publication number: 20170166874
    Abstract: The present invention provides PiggyBac transposase proteins, nucleic acids encoding the same, compositions comprising the same, kits comprising the same, non-human transgenic animals comprising the same, and methods of using the same.
    Type: Application
    Filed: July 28, 2016
    Publication date: June 15, 2017
    Inventors: Eric Ostertag, Blair Madison
  • Hyperactive piggybac transposases
    Patent number: 9546382
    Abstract: The present invention provides PiggyBac transposase proteins, nucleic acids encoding the same, compositions comprising the same, kits comprising the same, non-human transgenic animals comprising the same, and methods of using the same.
    Type: Grant
    Filed: February 22, 2013
    Date of Patent: January 17, 2017
    Assignee: Poseida Therapeutics, Inc.
    Inventors: Eric Ostertag, Blair Madison
  • VCSEL array for a depth camera
    Patent number: 9456201
    Abstract: Various embodiments relating to a time-of-flight (TOF) depth camera including a vertical-cavity surface emitting laser (VCSEL) array device are disclosed. In one embodiment, a TOF depth camera includes a heat sink having a mounting surface, an illumination module mounted to the mounting surface, and an image sensor mounted to the mounting surface. The illumination module includes a printed circuit board (PCB), a VCSEL array device configured to generate illumination light to illuminate an image environment, and a driver configured to deliver an operating current to the VCSEL array device. The VCSEL array device and the driver are mounted to the PCB. The image sensor is configured to detect at least a portion of illumination light reflected from the image environment.
    Type: Grant
    Filed: February 10, 2014
    Date of Patent: September 27, 2016
    Assignee: MICROSOFT TECHNOLOGY LICENSING, LLC
    Inventors: Prafulla Masalkar, Marshall T. DePue, Zhaoming Zhu, Sridhar Canumalla, Eric Paul Filer, Blair Madison Kent, John W. Mensonides
  • VCSEL ARRAY FOR A DEPTH CAMERA
    Publication number: 20150229912
    Abstract: Various embodiments relating to a time-of-flight (TOF) depth camera including a vertical-cavity surface emitting laser (VCSEL) array device are disclosed. In one embodiment, a TOF depth camera includes a heat sink having a mounting surface, an illumination module mounted to the mounting surface, and an image sensor mounted to the mounting surface. The illumination module includes a printed circuit board (PCB), a VCSEL array device configured to generate illumination light to illuminate an image environment, and a driver configured to deliver an operating current to the VCSEL array device. The VCSEL array device and the driver are mounted to the PCB. The image sensor is configured to detect at least a portion of illumination light reflected from the image environment.
    Type: Application
    Filed: February 10, 2014
    Publication date: August 13, 2015
    Applicant: Microsoft Corporation
    Inventors: Prafulla Masalkar, Marshall T. DePue, Zhaoming Zhu, Sridhar Canumalla, Eric Paul Filer, Blair Madison Kent, John W. Mensonides
  • Hyperactive Piggybac Transposases
    Publication number: 20130160152
    Abstract: The present invention provides PiggyBac transposase proteins, nucleic acids encoding the same, compositions comprising the same, kits comprising the same, non-human transgenic animals comprising the same, and methods of using the same.
    Type: Application
    Filed: February 22, 2013
    Publication date: June 20, 2013
    Applicant: Transposagen Biopharmaceuticals, Inc.
    Inventors: Eric Ostertag, Blair Madison
  • Nucleic acids encoding hyperactive PiggyBac transposases
    Patent number: 8399643
    Abstract: The present invention provides PiggyBac transposase proteins, nucleic acids encoding the same, compositions comprising the same, kits comprising the same, non-human transgenic animals comprising the same, and methods of using the same.
    Type: Grant
    Filed: February 25, 2010
    Date of Patent: March 19, 2013
    Assignee: Transposagen Biopharmaceuticals, Inc.
    Inventors: Eric Ostertag, Blair Madison
  • Hyperactive PiggyBac Transposases
    Publication number: 20100287633
    Abstract: The present invention provides PiggyBac transposase proteins, nucleic acids encoding the same, compositions comprising the same, kits comprising the same, non-human transgenic animals comprising the same, and methods of using the same.
    Type: Application
    Filed: February 25, 2010
    Publication date: November 11, 2010
    Applicant: TRANSPOSAGEN BIO
    Inventors: Eric Ostertag, Blair Madison