Patents by Inventor Blair R. Renshaw

Blair R. Renshaw has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bispecific Tetravalent Antibodies and Methods of Making and Using Thereof
    Publication number: 20210277128
    Abstract: A bispecific tetravalent antibody comprising an IgG having a pair of heavy chains and a pair of light chains, and two scFv components being connected to either C or N terminals of the heavy or light chains. The bispecific tetravalent antibody may have a binding specificity for two different members of EGFR family.
    Type: Application
    Filed: January 7, 2021
    Publication date: September 9, 2021
    Inventors: Zeren Gao, Phil Tan, Brian R. Kovacevich, Blair R. Renshaw, Jeffrey B. Adamo, Nga Sze Amanda Mak, Shi Zhuo, Lan Chen, Yi Zhu
  • Bispecific tetravalent antibodies and methods of making and using thereof
    Patent number: 10919977
    Abstract: A bispecific tetravalent antibody comprising an IgG having a pair of heavy chains and a pair of light chains, and two scFv components being connected to either C or N terminals of the heavy or light chains. The bispecific tetravalent antibody may have a binding specificity for two different members of EGFR family.
    Type: Grant
    Filed: December 19, 2015
    Date of Patent: February 16, 2021
    Assignees: SYSTIMMUNE, INC., Sichuan Baili Pharmaceutical Co. Ltd.
    Inventors: Zeren Gao, Phil Tan, Brian R. Kovacevich, Blair R. Renshaw, Jeffrey B. Adamo, Nga Sze Amanda Mak, Shi Zhuo, Lan Chen, Yi Zhu
  • Bispecific tetravalent antibodies and methods of making and using thereof
    Patent number: 10717783
    Abstract: A bispecific tetravalent antibody comprising an IgG having a pair of heavy chains and a pair of light chains, and two scFv components being connected to either C or N terminals of the heavy or light chains. The bispecific tetravalent antibody may have a binding specificity for two different epitopes on HER2 receptor.
    Type: Grant
    Filed: December 19, 2015
    Date of Patent: July 21, 2020
    Inventors: Zeren Gao, Yi Zhu, Phil Tan, Blair R. Renshaw, Brian R. Kovacevich
  • Bispecific Tetravalent Antibodies and Methods of Making and Using Thereof
    Publication number: 20170369587
    Abstract: A bispecific tetravalent antibody comprising an IgG having a pair of heavy chains and a pair of light chains, and two scFv components being connected to either C or N terminals of the heavy or light chains. The bispecific tetravalent antibody may have a binding specificity for two different epitopes on HER2 receptor.
    Type: Application
    Filed: December 19, 2015
    Publication date: December 28, 2017
    Inventors: Zeren Gao, Yi Zhu, Phil Tan, Blair R. Renshaw, Brian R. Kovacevich
  • Bispecific Tetravalent Antibodies and Methods of Making and Using Thereof
    Publication number: 20170073418
    Abstract: A bispecific tetravalent antibody comprising an IgG having a pair of heavy chains and a pair of light chains, and two scFv components being connected to either C or N terminals of the heavy or light chains. The bispecific tetravalent antibody may have a binding specificity for two different members of EGFR family.
    Type: Application
    Filed: December 19, 2015
    Publication date: March 16, 2017
    Inventors: Zeren Gao, Phil Tan, Brian R. Kovacevich, Blair R. Renshaw, Jeffrey B. Adamo, Nga Sze Amanda Mak, Shi Zhuo, Lan Chen
  • IL-1 FAMILY VARIANTS
    Publication number: 20160137708
    Abstract: The present invention provides compositions and methods relating to IL-1Rrp2 requiring proteins.
    Type: Application
    Filed: January 22, 2016
    Publication date: May 19, 2016
    Applicant: Amgen Inc.
    Inventors: John E. Sims, Blair R. Renshaw, Christopher Gabel, Jennifer E. Towne, Randal R. Ketchum
  • IL-1 FAMILY VARIANTS
    Publication number: 20150017123
    Abstract: The present invention provides compositions and methods relating to IL-1Rrp2 requiring proteins.
    Type: Application
    Filed: September 22, 2014
    Publication date: January 15, 2015
    Inventors: John E. SIMS, Blair R. RENSHAW, Christopher GABEL, Jennifer E. TOWNE, Randal R. KETCHEM
  • IL-1F8 polypeptides
    Patent number: 8871192
    Abstract: The present invention provides compositions and methods relating to IL-1Rrp2 requiring proteins.
    Type: Grant
    Filed: June 11, 2013
    Date of Patent: October 28, 2014
    Assignee: Amgen Inc.
    Inventors: John E. Sims, Blair R. Renshaw, Christopher Gabel, Jennifer E. Towne, Randal R. Ketchem
  • IL-1 FAMILY VARIANTS
    Publication number: 20130336926
    Abstract: The present invention provides compositions and methods relating to IL-1Rrp2 requiring proteins.
    Type: Application
    Filed: June 11, 2013
    Publication date: December 19, 2013
    Applicant: Amgen Inc.
    Inventors: John E. SIMS, Blair R. RENSHAW, Christopher GABEL, Jennifer E. TOWNE, Randal R. KETCHEM
  • IL-1F5 polypeptides
    Patent number: 8481021
    Abstract: The present invention provides compositions and methods relating to IL-1Rrp2 requiring proteins.
    Type: Grant
    Filed: September 2, 2011
    Date of Patent: July 9, 2013
    Assignee: Amgen Inc.
    Inventors: John E Sims, Blair R Renshaw, Christopher Gabel, Jennifer E. Towne, Randal R Ketchem
  • IL-1 FAMILY VARIANTS
    Publication number: 20120020918
    Abstract: The present invention provides compositions and methods relating to IL-1Rrp2 requiring proteins.
    Type: Application
    Filed: September 2, 2011
    Publication date: January 26, 2012
    Applicant: Amgen Inc.
    Inventors: John E. Sims, Blair R. Renshaw, Christopher Gabel, Jennifer E. Towne, Randal R. Ketchem
  • IL-1F6 polypeptides
    Patent number: 8034771
    Abstract: The present invention provides compositions and methods relating to IL-1Rrp2 requiring proteins.
    Type: Grant
    Filed: September 10, 2007
    Date of Patent: October 11, 2011
    Assignee: Amgen Inc.
    Inventors: John E. Sims, Blair R. Renshaw, Christopher Gabel, Jennifer E. Towne, Randal R. Ketchem
  • IL-1 ETA DNA AND POLYPEPTIDES
    Publication number: 20090232816
    Abstract: The invention is directed to novel purified and isolated IL-1 eta polypeptides and fragment thereof, the polynucleotides encoding such, polypeptides, processes for production of recombinant forms of such polypeptides, antibodies generated against these polypeptides, peptides derived from these polypeptides, and uses thereof.
    Type: Application
    Filed: May 24, 2007
    Publication date: September 17, 2009
    Applicant: IMMUNEX CORPORATION
    Inventors: JOHN E. SIMS, BLAIR R. RENSHAW
  • IL-1 family variants
    Publication number: 20080241096
    Abstract: The present invention provides compositions and methods relating to IL-1Rrp2 requiring proteins.
    Type: Application
    Filed: September 10, 2007
    Publication date: October 2, 2008
    Applicant: Amgen Inc.
    Inventors: John E. Sims, Blair R. Renshaw, Christopher Gabel, Jennifer E. Towne, Randal R. Ketchem
  • IL-1 eta DNA and polypeptides
    Patent number: 7235637
    Abstract: The invention is directed to novel, purified and isolated IL-1 eta polypeptides and fragments thereof, the polynucleotides encoding such polypeptides, processes for production of recombinant forms of such polypeptides, antibodies generated against these polypeptides, peptides derived from these polypeptides, and uses thereof.
    Type: Grant
    Filed: May 10, 2004
    Date of Patent: June 26, 2007
    Assignee: Immunex Corporation
    Inventors: John E. Sims, Blair R. Renshaw
  • IL-1 eta DNA and polypeptides
    Patent number: 7223565
    Abstract: The invention is directed to novel, purified and isolated IL-1 eta polypeptides and fragments thereof, the polynucleotides encoding such polypeptides, processes for production of recombinant forms of such polypeptides, antibodies generated against these polypeptides, peptides derived from these polypeptides, and uses thereof.
    Type: Grant
    Filed: May 10, 2004
    Date of Patent: May 29, 2007
    Assignee: Immunex Corporation
    Inventors: John E. Sims, Blair R. Renshaw
  • Il-1 eta DNA and polypeptides
    Publication number: 20040210038
    Abstract: The invention is directed to novel, purified and isolated IL-1 eta polypeptides and fragments thereof, the polynucleotides encoding such polypeptides, processes for production of recombinant forms of such polypeptides, antibodies generated against these polypeptides, peptides derived from these polypeptides, and uses thereof.
    Type: Application
    Filed: May 10, 2004
    Publication date: October 21, 2004
    Applicant: Immunex Corp.
    Inventors: John E. Sims, Blair R. Renshaw
  • IL-1 eta DNA and polypeptides
    Publication number: 20040203116
    Abstract: The invention is directed to novel, purified and isolated IL-1 eta polypeptides and fragments thereof, the polynucleotides encoding such polypeptides, processes for production of recombinant forms of such polypeptides, antibodies generated against these polypeptides, peptides derived from these polypeptides, and uses thereof.
    Type: Application
    Filed: May 10, 2004
    Publication date: October 14, 2004
    Applicant: Immunex Corp.
    Inventors: John E. Sims, Blair R. Renshaw
  • IL-1 eta DNA and polypeptides
    Patent number: 6753166
    Abstract: The invention is directed to novel, purified and isolated IL-1 eta polypeptides and fragments thereof, the polynucleotides encoding such polypeptides, processes for production of recombinant forms of such polypeptides, antibodies generated against these polypeptides, peptides derived from these polypeptides, and uses thereof.
    Type: Grant
    Filed: October 11, 2001
    Date of Patent: June 22, 2004
    Assignee: Immunex Corporation
    Inventors: John E. Sims, Blair R. Renshaw
  • Defective CD4+T-cells that express active CD40-L
    Patent number: 6613320
    Abstract: CD4+ cells obtained from individuals with defective CD40L gene and transfected with a vector containing CD40-L are described.
    Type: Grant
    Filed: April 10, 2000
    Date of Patent: September 2, 2003
    Assignee: Immunex Corporation
    Inventors: Melanie K. Spriggs, Richard J. Armitage, William C. Fanslow, III, Michael B. Widmer, Barry L. Davison, Blair R. Renshaw