Patents by Inventor Blaise Corthesy

Blaise Corthesy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for affecting infections
    Patent number: 10829542
    Abstract: The invention relates to methods promoting the aggregation of Salmonella bacteria in the gut of subjects, thereby providing immune exclusion and limiting bacterial entry, therefore reducing mucosal and systemic infection.
    Type: Grant
    Filed: December 20, 2017
    Date of Patent: November 10, 2020
    Assignees: CSL BEHRING AG, CENTRE HOSPITALIER UNIVERSITAIRE VAUDOIS
    Inventors: Blaise Corthésy, Gilles Bioley, Cédric Pierre Vonarburg
  • Gas-filled microvesicles for use as vaccine
    Patent number: 10537622
    Abstract: Gas-filled microvesicles comprising an antigen bound thereto and to aqueous suspensions containing said microvesicles, for use in immunomodulating formulations, in particular as a vaccine. The antigen is covalently bound to a component of the microvesicles envelope. The microvesicles of the invention, comprising a molar excess of fatty acids in the stabilizing envelope, are particularly effective in the uptake by antigen-presenting cells, in particular dendritic cells.
    Type: Grant
    Filed: December 21, 2015
    Date of Patent: January 21, 2020
    Assignee: BRACCO SUISSE S.A.
    Inventors: Gilles Bioley, Philippe Bussat, Blaise Corthesy, Anne Lassus
  • Probiotics, secretory IgA and inflammation
    Patent number: 10501530
    Abstract: Probiotics and ways to increase their effectiveness are provided. One embodiment of the present invention relates to a combination of probiotics with SIgA and possible uses of this combination. For example a use of a composition comprising SIgA and at least one probiotic for the preparation of a product to treat or prevent inflammation is disclosed.
    Type: Grant
    Filed: October 19, 2017
    Date of Patent: December 10, 2019
    Assignee: Societe des Produits Nestle S.A.
    Inventors: Jalil Benyacoub, Blaise Corthesy, Stephanie Blum-Sperisen, Laurent Favre
  • METHODS FOR AFFECTING SALMONELLA INFECTIONS
    Publication number: 20190345229
    Abstract: The invention relates to methods promoting the aggregation of Salmonella bacteria in the gut of subjects, thereby providing immune exclusion and limiting bacterial entry, therefore reducing mucosal and systemic infection.
    Type: Application
    Filed: December 20, 2017
    Publication date: November 14, 2019
    Applicants: CSL BEHRING AG, CENTRE HOSPITALIER UNIVERSITAIRE VAUDOIS
    Inventors: Blaise CORTHÉSY, Gilles BIOLEY, Cédric Pierre VONARBURG
  • Compositions comprising secretory-like immunoglobulins
    Patent number: 10221233
    Abstract: The invention relates to methods for preparing compositions comprising secretory-like immunoglobulin, in particular secretory-like IgA and/or secretory-like IgM, and compositions obtainable by the methods.
    Type: Grant
    Filed: March 8, 2013
    Date of Patent: March 5, 2019
    Assignee: CSL BEHRING AG
    Inventors: Blaise Corthésy, Stéphanie Longet, Marius Loetscher, Sylvia Miescher, Adrian Zuercher
  • PROBIOTICS, SECRETORY IgA AND INFLAMMATION
    Publication number: 20180037637
    Abstract: Probiotics and ways to increase their effectiveness are provided. One embodiment of the present invention relates to a combination of probiotics with SIgA and possible uses of this combination. For example a use of a composition comprising SIgA and at least one probiotic for the preparation of a product to treat or prevent inflammation is disclosed.
    Type: Application
    Filed: October 19, 2017
    Publication date: February 8, 2018
    Inventors: Jalil Benyacoub, Blaise Corthesy, Stephanie Blum-Sperisen, Laurent Favre
  • GAS-FILLED MICROVESICLES FOR USE AS VACCINE
    Publication number: 20170348401
    Abstract: Gas-filled microvesicles comprising an antigen bound thereto and to aqueous suspensions containing said microvesicles, for use in immunomodulating formulations, in particular as a vaccine. The antigen is covalently bound to a component of the microvesicles envelope. The microvesicles of the invention, comprising a molar excess of fatty acids in the stabilizing envelope, are particularly effective in the uptake by antigen-presenting cells, in particular dendritic cells.
    Type: Application
    Filed: December 21, 2015
    Publication date: December 7, 2017
    Applicant: BRACCO SUISSE S.A.
    Inventors: Gilles BIOLEY, Philippe BUSSAT, Blaise CORTHESY, Anne LASSUS
  • Probiotics, secretory IgA and inflammation
    Patent number: 9822167
    Abstract: The present invention relates generally to the field of nutrition, health and wellness. In particular the present invention relates to probiotics and ways to increase their effectiveness. One embodiment of the present invention relates to a combination of probiotics with SIgA and possible uses of this combination. For example a use of a composition comprising SIgA and at least one probiotic for the preparation of a product to treat or prevent inflammation is disclosed.
    Type: Grant
    Filed: June 16, 2009
    Date of Patent: November 21, 2017
    Assignee: Nestec S.A.
    Inventors: Jalil Benyacoub, Blaise Corthesy, Stephanie Blum-Sperisen, Laurent Favre
  • Allergen peptide fragments and use thereof for treatment of birch pollen allergies
    Patent number: 9808503
    Abstract: The present invention relates generally to in vivo methods and compositions designed for allergen specific immunotherapy. The compositions include contiguous overlapping peptide fragments which together form an entire amino acid sequence of an allergen.
    Type: Grant
    Filed: November 23, 2015
    Date of Patent: November 7, 2017
    Assignee: ANERGIS S.A.
    Inventors: Francois Spertini, Blaise Corthesy
  • PROBIOTICS, SECRETORY IgA AND INFECTION
    Publication number: 20170281757
    Abstract: Ways to increase the effectiveness of probiotics are disclosed. One embodiment relates to a combination of probiotics with secretory IgA and possible uses of this combination. For example, a method of using a composition containing secretory IgA and at least one probiotic to prepare a product to treat or prevent infection is disclosed.
    Type: Application
    Filed: March 24, 2017
    Publication date: October 5, 2017
    Inventors: Jalil Benyacoub, Blaise Corthesy, Stephanie Blum-Sperisen, Laurent Favre
  • Methods of using gas-filled microvesicles covalently bound to an antigen
    Patent number: 9770411
    Abstract: Gas-filled microvesicles comprising an antigen bound thereto and to aqueous suspensions containing said microvesicles, for use in immunomodulating formulations, in particular as a vaccine. The antigen is covalently bound to a component of the microvesicles envelope. The microvesicles of the invention are particularly effective in the uptake by antigen-presenting cells, in particular dendritic cells.
    Type: Grant
    Filed: December 21, 2011
    Date of Patent: September 26, 2017
    Assignee: Bracco Suisse S.A.
    Inventors: Gilles Bioley, Blaise Corthesy, Philippe Bussat, Anne Lassus, Michel Schneider
  • Probiotics, secretory IgA and infection
    Patent number: 9629908
    Abstract: Ways to increase the effectiveness of probiotics is disclosed. One embodiment relates to a combination of probiotics with secretory IgA and possible uses of this combination. For example, a method of using a composition comprising secretory IgA and at least one probiotic to prepare a product to treat or prevent infection is disclosed.
    Type: Grant
    Filed: October 1, 2015
    Date of Patent: April 25, 2017
    Assignee: Nestec S.A.
    Inventors: Jalil Benyacoub, Blaise Corthesy, Stephanie Blum-Sperisen, Laurent Favre
  • PROBIOTICS, SECRETORY IgA AND INFECTION
    Publication number: 20160106834
    Abstract: Ways to increase the effectiveness of probiotics is disclosed. One embodiment relates to a combination of probiotics with secretory IgA and possible uses of this combination. For example, a method of using a composition comprising secretory IgA and at least one probiotic to prepare a product to treat or prevent infection is disclosed.
    Type: Application
    Filed: October 1, 2015
    Publication date: April 21, 2016
    Inventors: Jalil Benyacoub, Blaise Corthesy, Stephanie Blum-Sperisen, Laurent Favre
  • Allergen Peptide Fragments and Use Thereof for Treatment of Birch Pollen Allergies
    Publication number: 20160095899
    Abstract: The present invention relates generally to in vivo methods and compositions designed for allergen specific immunotherapy. The compositions include contiguous overlapping peptide fragments which together form an entire amino acid sequence of an allergen.
    Type: Application
    Filed: November 23, 2015
    Publication date: April 7, 2016
    Inventors: Francois Spertini, Blaise Corthesy
  • Allergen peptide fragments and use thereof for treatment of dust mite allergies
    Patent number: 9193773
    Abstract: The present invention relates generally to in vivo methods and compositions designed for allergen specific immunotherapy. The compositions include contiguous overlapping peptide fragments which together form an entire amino acid sequence of an allergen.
    Type: Grant
    Filed: March 12, 2014
    Date of Patent: November 24, 2015
    Assignee: ANERGIS S.A..
    Inventors: Francois Spertini, Blaise Corthesy
  • Probiotics, secretory IgA and infection
    Patent number: 9173937
    Abstract: The present invention relates generally to the field of nutrition, health and wellness. In particular the present invention relates to probiotics and ways to increase their effectiveness. One embodiment of the present invention relates to a combination of probiotics with secretory IgA and possible uses of this combination. For example a use of a composition comprising secretory IgA and at least one probiotic for the preparation of a product to treat or prevent infection is disclosed.
    Type: Grant
    Filed: June 16, 2009
    Date of Patent: November 3, 2015
    Assignee: Nestec S.A.
    Inventors: Jalil Benyacoub, Blaise Corthesy, Stephanie Blum-Sperisen, Laurent Favre
  • COMPOSITIONS COMPRISING SECRETORY - LIKE IMUNOGLOBULINS
    Publication number: 20150056180
    Abstract: The invention relates to methods for preparing compositions comprising secretory-like immunoglobulin, in particular secretory-like IgA and/or secretory-like IgM, and compositions obtainable by the methods.
    Type: Application
    Filed: March 8, 2013
    Publication date: February 26, 2015
    Inventors: Blaise Corthésy, Stéphanie Longet, Marius Lötscher, Sylvia Miescher, Adrian Zürcher
  • PROCESS FOR PREPARATION OF SECRETORY IgA AND SECRETORY IgM
    Publication number: 20140371431
    Abstract: A process for synthesizing and separating secretory IgA from a mixture of IgA monomer and IgA dimer is provided. The process includes covalently binding affinity tagged or epitope tagged recombinant secretory component to the IgA dimer in the mixture and binding the affinity tagged or an epitope tagged secretory IgA to immobilized moieties on the solid phase support resin to which the affinity tag or epitope tag binds and then eluting the affinity tagged or an epitope tagged secretory IgA with release buffer. A process for synthesizing and separating secretory IgM from a mixture of IgM and other plasma proteins is also provided. The process includes covalently binding affinity tagged or an epitope tagged recombinant secretory component to the IgM in the mixture and binding the affinity tagged or an epitope tagged secretory IgM to immobilized moieties on the solid phase support resin and then eluting the peptide tagged secretory IgM with a release buffer.
    Type: Application
    Filed: September 3, 2014
    Publication date: December 18, 2014
    Inventors: Stephen C. Brown, Michael R. Simon, Blaise Corthésy
  • ALLERGEN PEPTIDE FRAGMENTS AND USE THEREOF FOR TREATMENT OF DUST MITE ALLERGIES
    Publication number: 20140193444
    Abstract: The present invention relates generally to in vivo methods and compositions designed for allergen specific immunotherapy. The compositions include contiguous overlapping peptide fragments which together form an entire amino acid sequence of an allergen.
    Type: Application
    Filed: March 12, 2014
    Publication date: July 10, 2014
    Applicant: ANERGIS S.A.
    Inventors: Francois Spertini, Blaise Corthesy
  • Allergen peptide fragments and use thereof for treatment of dust mite allergies
    Patent number: 8703144
    Abstract: The present invention relates generally to in vivo methods and compositions designed for allergen specific immunotherapy. The compositions include contiguous overlapping peptide fragments which together form an entire amino acid sequence of an allergen.
    Type: Grant
    Filed: October 28, 2011
    Date of Patent: April 22, 2014
    Assignee: Anergis S.A.
    Inventors: Francois Spertini, Blaise Corthesy