Patents by Inventor Blaise deB. Frederick

Blaise deB. Frederick has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Generation of synthetic nuclear magnetic resonance signals
    Patent number: 6861840
    Abstract: The invention involves an active phantom that transmits a waveform based on data reflecting free induction decay signals. The methods and apparatuses of the invention can be used, for example, to test and calibrate a magnetic resonance scanner; evaluate image acquisition parameters and reconstruction algorithms; and train scanner operators. In addition, the invention can simulate complex samples, e.g., a human brain without requiring human subject available to submit to the time and discomfort of a magnetic resonance scan.
    Type: Grant
    Filed: July 20, 2001
    Date of Patent: March 1, 2005
    Assignee: McLean Hospital Corporation
    Inventors: Blaise deB. Frederick, Michael L. Rohan
  • Magnetic resonance with stimulation
    Publication number: 20030229107
    Abstract: This invention involves blood oxygen level dependent (BOLD) functional magnetic resonance imaging (fMRI) using external stimuli. Different colors of light can be used as the stimulus to assess differential BOLD response to diagnose neurological disorders (e.g., Parkinson's disease, attention deficit disorder, schizophrenia, and substance abuse). In addition, very low dose administration of a drug that affects intracerebral vasculature can enhance BOLD response, facilitating detection and improving diagnostic capabilities. Using a very low dose of d-amphetamine, BOLD response to blue light is increased.
    Type: Application
    Filed: November 1, 2002
    Publication date: December 11, 2003
    Inventors: Ronald Cowan, Perry Renshaw, Blaise deB. Frederick, Scott Lukas
  • Generation of synthetic nuclear magnetic resonance signals
    Publication number: 20030016014
    Abstract: The invention involves an active phantom that transmits a waveform based on data reflecting free induction decay signals. The methods and apparatuses of the invention can be used, for example, to test and calibrate a magnetic resonance scanner; evaluate image acquisition parameters and reconstruction algorithms; and train scanner operators. In addition, the invention can simulate complex samples, e.g., a human brain without requiring human subject available to submit to the time and discomfort of a magnetic resonance scan.
    Type: Application
    Filed: July 20, 2001
    Publication date: January 23, 2003
    Inventors: Blaise deB. Frederick, Michael L. Rohan
  • Phased array echoplanar imaging system for fMRI
    Patent number: 6104943
    Abstract: The design and construction of a novel phased array echoplanar receiver system for magnetic resonance imaging for use with a standard clinical EPI system is described, and in vivo results showing increased SNR are presented.
    Type: Grant
    Filed: November 14, 1997
    Date of Patent: August 15, 2000
    Assignee: The McLean Hospital Corporation
    Inventors: Blaise deB. Frederick, Lawrence Wald, Perry F. Renshaw
  • Registration of image data
    Patent number: 5850486
    Abstract: Registration of images includes rotational and translation correction. Rotational correction includes estimating a rotational-correction angle by polar K-space cross-correlation. K-space regridding is used to rotate an image by the estimated correction angle. Translational correction is obtained by K-space phase-plane conjugation.
    Type: Grant
    Filed: April 29, 1996
    Date of Patent: December 15, 1998
    Assignee: The McLean Hospital Corporation
    Inventors: Luis C. Maas, III, Blaise deB. Frederick, Perry F. Renshaw