Abstract: A method of presenting media content is disclosed. A plurality of assets is received at a device comprising a display and an orientation sensor. The plurality of assets comprises a first video asset associated with a first aspect ratio, and a second video asset associated with a second aspect ratio, different from the first aspect ratio. A desired aspect ratio is determined based on an output of the orientation sensor. In accordance with a determination that the desired aspect ratio is closer to the first aspect ratio than to the second aspect ratio, the first video asset is selected. In accordance with a determination that the desired aspect ratio is closer to the second aspect ratio than to the first aspect ratio, the second video asset is selected. The selected video is presented at the desired aspect ratio via the display.

Abstract: The present disclosure provides CRISPR systems using engineered MAD7 endonucleases, as well as methods, vectors, nucleic acid compositions, and kits thereof. In particular, provided herein are MAD7 nickases, catalytically dead MAD7 enzymes, and hyperactive MAD7 enzymes.

Abstract: A method of presenting media content is disclosed. A plurality of assets is received at a mobile device comprising a display and an orientation sensor. The plurality of assets comprises a first video asset associated with a first aspect ratio, and a second video asset associated with a second aspect ratio, different from the first aspect ratio. A desired aspect ratio is determined based on an output of the orientation sensor. In accordance with a determination that the desired aspect ratio is closer to the first aspect ratio than to the second aspect ratio, the first video asset is selected. In accordance with a determination that the desired aspect ratio is closer to the second aspect ratio than to the first aspect ratio, the second video asset is selected. The selected video is presented at the desired aspect ratio via the display.

Abstract: A method of presenting media content is disclosed. A plurality of assets is received at a mobile device comprising a display and an orientation sensor. The plurality of assets comprises a first video asset associated with a first aspect ratio, and a second video asset associated with a second aspect ratio, different from the first aspect ratio. A desired aspect ratio is determined based on an output of the orientation sensor. In accordance with a determination that the desired aspect ratio is closer to the first aspect ratio than to the second aspect ratio, the first video asset is selected. In accordance with a determination that the desired aspect ratio is closer to the second aspect ratio than to the first aspect ratio, the second video asset is selected. The selected video is presented at the desired aspect ratio via the display.

Abstract: A trade transaction agreement, defined as a basket, of one or more structured products, may be converted into one or more structured products. Trade information that represents the trade transaction agreement may be initially provided or specified in various forms, to subsequently be analyzed to construct the trade transaction agreement into its corresponding structured products. The structured products are suitable for submission to post-trade processing facilities for subsequent processing thereof and are accordingly submitted. The structured products may be submitted to a variety of post-trade processing facilities, or one post-trade processing facility may be utilized.

Abstract: Multiple financial product quotes for a particular product are aggregated into a product unit display, providing for user configuration related to a display of the quotes. A first sort attribute and a second sort attribute are selected or configured to provide the user with a display that includes the financial product quotes in groupings according to the first sort attribute and in ordered lists according to the second sort attribute. When a financial product quote is received, the quote is grouped with other financial product quotes for the particular product according to a first sort attribute. Each grouping is then ordered according to a second sort attribute to provide the desired product unit display. Various sources may provide the quotes, and extra information to enrich the quotes may be provided. Various indicators may be used to highlight or emphasize certain types of information in the product unit display.

Abstract: A trade transaction agreement, defined as a basket of one or more structured products, may be converted into one or more structured products. Trade information that represents the trade transaction agreement may be initially provided or specified in various forms, to subsequently be analyzed to construct the trade transaction agreement into its corresponding structured products. The structured products are suitable for submission to post-trade processing facilities for subsequent processing thereof and are accordingly submitted. The structured products may be submitted to a variety of post-trade processing facilities, or one post-trade processing facility may be utilized.