Patents by Inventor Blanche Ip

Blanche Ip has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Funnel-guided microtissue stacking and manipulation
    Patent number: 11286451
    Abstract: The invention provides a device and a method for the assembly of an aggregation of adherent cells, particularly a three-dimensional assembly of adherent cells.
    Type: Grant
    Filed: February 5, 2019
    Date of Patent: March 29, 2022
    Assignee: Brown University
    Inventors: Jeffrey R. Morgan, Kali L. Manning, Blanche Ip
  • A MULTI-COMPARTMENT DEVICE CONTAINING HUMAN THREE-DIMENSIONAL (3D) MICROTISSUES FOR TOXICITY TESTING
    Publication number: 20220081659
    Abstract: This dual-compartment liver co-culture system exposes target microtissue to metabolites, allowing for evaluating toxicity using a standard multi-well plate for high throughput analysis. Discovery scientists can rapidly select lead compounds with desirable metabolic profiles, while safety scientists can determine the safety of drugs, pesticides, and environmental chemicals. This platform is allometrically scalable, so it can mimic the natural size differences between healthy organs and, with the liver, produce sufficient quantities of metabolites. The device is simple to use and designed for immediate in vitro pathology assessment using confocal microscopy, transcriptomics, and proteomics.
    Type: Application
    Filed: January 9, 2020
    Publication date: March 17, 2022
    Inventors: Kim BOEKELHEIDE, Jeffrey MORGAN, Susan HALL, Hui LI, Blanche IP
  • FUNNEL-GUIDED MICROTISSUE STACKING AND MANIPULATION
    Publication number: 20200377835
    Abstract: The invention provides a device and a method for the assembly of an aggregation of adherent cells, particularly a three-dimensional assembly of adherent cells.
    Type: Application
    Filed: February 5, 2019
    Publication date: December 3, 2020
    Inventors: Jeffrey R. MORGAN, Kali L. MANNING, Blanche IP
  • Methods for determining glycemic responses of foods
    Publication number: 20050244910
    Abstract: The present invention provides precise methods for determining the glycemic responses of foods, including: (a) the incremental area under the glycemic response curve, (b) the Glycemic Index value of a food, (c) the Equivalent Glycemic Load or Glycemic Glucose Equivalent of a food, and (d) other similar measures.
    Type: Application
    Filed: May 2, 2005
    Publication date: November 3, 2005
    Inventors: Thomas Wolever, Blanche Ip, Elham Mogghadam-Bozorgi