Patents by Inventor Blenda Chi Kwan WONG

Blenda Chi Kwan WONG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Slow and controlled released liposomal gel composition comprising hypoglycemic active ingredient and method of preparing thereof
    Patent number: 9980906
    Abstract: The present invention provides a slow and controlled released liposomal gel composition for subcutaneous administration comprises insulin or exenatide as active ingredient for reduction of blood sugar level and method of preparation thereof. Said controlled released composition has high bioavailability and is demonstrated to be able to sustain release therapeutically effective concentration of drug over a period of time and without rapid release of drug after initial administration. Method of preparing the controlled released composition of the present invention comprises the following steps: mixing insulin or exenatide, lipid and aqueous dispersion medium together; then mixing with poloxamer (e.g. F127 or P123) and/or gelatin and hyaluronic acid (HA) or the like gel solution so as to form a protective layer on surface of every lipid micro vesicles or nano-vesicles for use in intramuscular, abdominal and subcutaneous administration.
    Type: Grant
    Filed: October 20, 2014
    Date of Patent: May 29, 2018
    Assignee: Hong Kong Baptist University
    Inventors: Zhijun Yang, Aiping Lu, Zhaoxiang Bian, Xiaoyu Chen, Blenda Chi Kwan Wong
  • SLOW AND CONTROLLED RELEASED LIPOSOMAL GEL COMPOSITION COMPRISING HYPOGLYCEMIC ACTIVE INGREDIENT AND METHOD OF PREPARING THEREOF
    Publication number: 20160074324
    Abstract: The present invention provides a slow and controlled released liposomal gel composition for subcutaneous administration comprises insulin or exenatide as active ingredient for reduction of blood sugar level and method of preparation thereof. Said controlled released composition has high bioavailability and is demonstrated to be able to sustain release therapeutically effective concentration of drug over a period of time and without rapid release of drug after initial administration. Method of preparing the controlled released composition of the present invention comprises the following steps: mixing insulin or exenatide, lipid and aqueous dispersion medium together; then mixing with poloxamer (e.g. F127 or P123) and/or gelatin and hyaluronic acid (HA) or the like gel solution so as to form a protective layer on surface of every lipid micro vesicles or nano-vesicles for use in intramuscular, abdominal and subcutaneous administration.
    Type: Application
    Filed: October 20, 2014
    Publication date: March 17, 2016
    Applicant: Hong Kong Baptist University
    Inventors: Zhijun YANG, Aiping LU, Zhaoxiang BIAN, Xiaoyu CHEN, Blenda Chi Kwan WONG