Patents by Inventor Bo Akerstrom

Bo Akerstrom has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • USE OF ALPHA-1-MICROGLOBULIN FOR PROTECTION OF BONE MARROW CELLS
    Publication number: 20200345810
    Abstract: The present invention relates to alpha-1-microglobulin (A1M) for use in the protection of bone marrow cells in a subject.
    Type: Application
    Filed: November 1, 2018
    Publication date: November 5, 2020
    Inventors: Johan Flygare, Eddie Thordarson, Bo Åkerström, Magnus Göran Gram
  • NOVEL ALPHA-1-MICROGLOBULIN DERIVED PROTEINS AND THEIR USE
    Publication number: 20190161524
    Abstract: This invention relates to an alpha-1-microglobulin derived protein for medical use.
    Type: Application
    Filed: March 17, 2017
    Publication date: May 30, 2019
    Applicant: A1 M Pharma AB
    Inventors: Lena Webster ROSENLÖF, Anneli Edström HÄGERWALL, Bo AKERSTRÖM
  • ALPHA-1-MICROGLOBULIN FOR USE IN THE PROTECTION OF KIDNEYS IN CONNECTION WITH USE OF CONTRAST MEDIA
    Publication number: 20190054142
    Abstract: This invention relates to an alpha-1-microglobulin for use in prevention of contras medium nephropathy.
    Type: Application
    Filed: February 24, 2017
    Publication date: February 21, 2019
    Applicant: A1M Pharma AB
    Inventors: Martin AUSTIN, Magnus Göran GRAM, Bo ÅKERSTRÖM
  • DIAGNOSIS AND TREATMENT OF PREECLAMPSIA
    Publication number: 20180284087
    Abstract: The present invention relates to biomarkers for preeclampsia as well as treatment of this disease. In particular, the invention relates to methods for diagnosis or aiding in the diagnosis of preeclampsia of a pregnant female mammal to detect elevated levels of free haemoglobin, particularly free fetal haemoglobin. This facilitates and makes possible early diagnosis and clinical intervention when a preeclamptic condition is found. In addition, the invention relates to a method to treat female mammals with preeclampsia with the purpose to reverse the pathological conditions associated with this disease.
    Type: Application
    Filed: January 26, 2018
    Publication date: October 4, 2018
    Applicant: A1M Pharma AB
    Inventors: Stephan HANSSON, Bo ÅKERSTRÖM
  • ALPHA-1-MICROGLOBULIN FOR USE IN THE PROTECTION OF KIDNEYS IN RADIONUCLIDE THERAPY
    Publication number: 20180243369
    Abstract: This invention relates to ?1-microglobulin (A1M) for use in the diagnosis or treatment of malignancies requiring radionuclide diagnostics (RD), radionuclide therapy (RNT) or radioimmunotherapy (RIT), respectively, wherein A1M is used as a co-treatment to RD, RNT or RIT.
    Type: Application
    Filed: February 25, 2016
    Publication date: August 30, 2018
    Applicant: A1M PHARMA AB
    Inventors: Bo Akerstrom, Sven-Erik STRAND, Magnus Göran GRAM, Amanda Thuy TRAN
  • BIOMARKERS FOR PREECLAMPSIA
    Publication number: 20180074070
    Abstract: The present invention relates to the use of hemopexin, free, non-cell bound fetal hemoglobin and alpha-1-micro-globulin as markers for preeclampsia.
    Type: Application
    Filed: March 16, 2016
    Publication date: March 15, 2018
    Applicant: A1M Pharma AB
    Inventors: Stefan HANSSON, Bo AKERSTRÖM, Magnus Göran GRAM
  • ALPHA-1-MICROGLOBULIN FOR USE IN THE TREATMENT OF MITOCHONDRIA-RELATED DISEASES
    Publication number: 20150258171
    Abstract: The present invention relates to alpha-1-microglobulin for use in the treatment of a mitochondria-related disease.
    Type: Application
    Filed: September 4, 2013
    Publication date: September 17, 2015
    Applicant: A1M Pharma AB
    Inventors: Bo Åkerstrom, Magnus Gram, Lena Rosenlöf
  • DIAGNOSIS AND TREATMENT OF PREECLAMPSIA
    Publication number: 20140065170
    Abstract: The present invention relates to biomarkers for preeclampsia as well as treatment of this disease. In particular, the invention relates to methods for diagnosis or aiding in the diagnosis of preeclampsia of a pregnant female mammal to detect elevated levels of free haemoglobin, particularly free fetal haemoglobin. This facilitates and makes possible early diagnosis and clinical intervention when a preeclamptic condition is found. In addition, the invention relates to a method to treat female mammals with preeclampsia with the purpose to reverse the pathological conditions associated with this disease.
    Type: Application
    Filed: September 17, 2013
    Publication date: March 6, 2014
    Applicant: A1M Pharma AB
    Inventors: Stefan Hansson, Bo Akerström
  • Diagnosis and treatment of preeclampsia
    Patent number: 8568999
    Abstract: The present invention relates to biomarkers for preeclampsia as well as treatment of this disease. In particular, the invention relates to methods for diagnosis or aiding in the diagnosis of preeclampsia of a pregnant female mammal to detect elevated levels of free haemoglobin, particularly free fetal haemoglobin. This facilitates and makes possible early diagnosis and clinical intervention when a preeclamptic condition is found. In addition, the invention relates to a method to treat female mammals with preeclampsia with the purpose to reverse the pathological conditions associated with this disease.
    Type: Grant
    Filed: February 12, 2008
    Date of Patent: October 29, 2013
    Assignee: A1M Pharma AB
    Inventors: Stefan Hansson, Bo Akerstrom
  • HbF AND A1M AS EARLY STAGE MARKERS FOR PREECLAMPSIA
    Publication number: 20130122529
    Abstract: A method for diagnosing or predicting the risk of developing preeclampsia by measuring the level of A1 M and one or more of the compounds HbA, HbF in a sample and comparing the obtained values with reference values. By using a combination of information relating to A1 M and HbF improved diagnose or prediction is observed.
    Type: Application
    Filed: March 24, 2011
    Publication date: May 16, 2013
    Applicant: Preelumina Diagnostics AB
    Inventors: Bo Akerstrom, Magnus Gram, Stefan Hansson
  • MEDICAL USE OF THE RADICAL SCAVENGER AND ANTIOXIDANT ALPHA-1-MICROGLOBULIN
    Publication number: 20110190208
    Abstract: Medical use of alpha-1-microglobulin (A1M) in the treatment or prophylaxis of diseases wherein oxidative stress is a responsible factor in the progress of the disease. Notably, the present invention relates to the medical use of alpha-1-microglobulin in the treatment or prophylaxis of diseases or conditions associated with the presences of free radicals and/or free haemoglobin in the subject.
    Type: Application
    Filed: July 17, 2009
    Publication date: August 4, 2011
    Inventors: Bo Åkerström, Stefan Hanson, Martin Lennarth Olsson, Magnus Olsson
  • DIAGNOSIS AND TREATMENT OF PREECLAMPSIA
    Publication number: 20100105070
    Abstract: The present invention relates to biomarkers for preeclampsia as well as treatment of this disease. In particular, the invention relates to methods for diagnosis or aiding in the diagnosis of preeclampsia of a pregnant female mammal to detect elevated levels of free haemoglobin, particularly free fetal haemoglobin. This facilitates and makes possible early diagnosis and clinical intervention when a preeclamptic condition is found. In addition, the invention relates to a method to treat female mammals with preeclampsia with the purpose to reverse the pathological conditions associated with this disease.
    Type: Application
    Filed: February 12, 2008
    Publication date: April 29, 2010
    Inventors: Stefan Hansson, Bo Akerstrom
  • Temperature dependent ligand facilitated purification of proteins
    Patent number: 6380365
    Abstract: The invention concerns the use of a coiled coil protein which is capable of forming a homodimer which dissociates into monomers on change of temperature, in a method of isolating a ligand or desired protein from a sample. A method of isolating a ligand which binds to the coiled coil protein is described as well as methods of isolating a desired protein which is tagged with a coiled coil protein or a ligand which binds to a coiled coil protein, or is tagged with a coiled coil protein monomer.
    Type: Grant
    Filed: May 5, 1999
    Date of Patent: April 30, 2002
    Assignee: Affitech AS
    Inventors: Bo Akerström, Tommy Cedervall