Abstract: Provided herein are compounds and compositions for treating, managing or preventing coronaviral related diseases. In particular, provided herein are compounds which are inhibitors of SARS-CoV-2 main protease (Mpro), pharmaceutical compositions comprising such compounds, method for synthesizing such compounds and methods of using such compounds and compositions for the treatment, management or prevention of coronaviral related diseases.

Abstract: A display device, a gamma voltage data group switching method and module. The display device includes a display-driver integrated circuit and a first storage unit. The display-driver integrated circuit includes a second storage unit, and the display device includes a gamma voltage data group switching module. The gamma voltage data group switching module is configured to pre-store, in the first storage unit, multiple groups of gamma voltage data groups respectively applied to various application scenarios; when switching of an application scenario of the display device, load a gamma voltage data group corresponding to the current application scenario and stored in the first storage unit into the second storage unit.

Abstract: Systems and methods for interference signal collection and processing are provided. The systems may obtain initial signals and first interference signals collected in at least one first time window during an MR scan of a target subject. The nuclei in the target subject may be in an excited state in the at least one first time window. The initial signals may be collected by a receiving coil of an MRI device, and the first interference signals may be collected by an interference signal acquisition device. The systems may also determine second interference signals collected by the receiving coil in the at least one first time window based on the first interference signals. The systems may further determine imaging signals collected by the receiving coil in the at least one first time window by correcting the initial signals based on the second interference signals.

Abstract: A fan module includes a fan cover, a fixed grid coupled to the fan cover, a fan assembly positioned between the fan cover and the fixed grid, and at least one movable grid coupled to the fixed grid. The at least one movable grid is configured to move between an open position and a closed position. The fan module further includes a knob extending through the fan cover and the fixed grid. The knob is configured to move the at least one movable grid between the open position and the closed position. The knob includes an elongated portion, with the elongated portion being configured to prevent removal of the fan cover when the at least one movable grid is in the open position and permit removal of the fan cover when the at least one movable grid is in the closed position.

Abstract: A microfluidic device includes a substrate having a first fluid inlet/outlet system, a second fluid inlet/outlet system, and a fluidic network between the first fluid inlet/outlet system and the second fluid inlet/outlet system and in fluid communication with the first fluid inlet/outlet system and the second fluid inlet/outlet system. The fluidic network includes a microfluidic channel network that is in fluid communication with the first fluid inlet/outlet system and spaced from the second fluid inlet/outlet system, a nanofluidic channel network fluidly connecting the microfluidic channel network and the second fluid inlet/outlet system, and a plurality of pores in fluid communication with the microfluidic channel network and the nanofluidic channel network.

Abstract: A vehicle hitching assistance system includes a controller acquiring image data from the vehicle and deriving a vehicle path to align a center of a hitch ball of the vehicle with a centerline of a trailer coupler within the image data. The controller also outputs a video image including a representation of a simplified path from the hitch ball to the coupler and outputs a steering signal to cause the vehicle to steer along the vehicle path.

Abstract: A system for assisting in aligning a vehicle for hitching with a trailer includes a controller that identifies at least one of the trailer or a coupling feature of the trailer within image data and determines that the at least one of the trailer or the coupling feature is outside of a target position area relative to the vehicle and outputs an instruction for movement of the vehicle determined to position the one of the trailer or the coupling feature within the target position area in response to identifying at least one indication of a user difficulty in positioning the one of the trailer or the coupling feature within the target position area.

Abstract: A mobile device for remotely controlling the movement of a vehicle and trailer is provided. The mobile device provides a user engagement input for display and use of a control input. The control input may be used to generate a signal for controlling the movement of the vehicle and trailer.

Abstract: A microfluidic device includes a substrate having a first fluid inlet/outlet system, a second fluid inlet/outlet system, and a fluidic network between the first fluid inlet/outlet system and the second fluid inlet/outlet system and in fluid communication with the first fluid inlet/outlet system and the second fluid inlet/outlet system. The fluidic network includes a microfluidic channel network that is in fluid communication with the first fluid inlet/outlet system and spaced from the second fluid inlet/outlet system, a nanofluidic channel network fluidly connecting the microfluidic channel network and the second fluid inlet/outlet system, and a plurality of pores in fluid communication with the microfluidic channel network and the nanofluidic channel network.

Abstract: A vehicle hitching assistance system includes a controller executing an initial alignment process including searching for a trailer within a specified area of image data that is less than a total field of the image data in directions corresponding with both a longitudinal distance between the vehicle and the trailer and a lateral direction perpendicular to the longitudinal distance, presenting an indication to a driver of the vehicle to reposition the vehicle when the trailer is not identified within the specified area, and removing the indication when the trailer is identified within the specified area. The controller further executes an automated backing process upon identifying the trailer within the specified area, including identifying a coupler of the trailer and outputting a steering signal to the vehicle to cause the vehicle to steer to align a hitch ball of the vehicle with the coupler of the trailer during reversing.

Abstract: A vehicle hitching assistance system includes a controller executing an initial alignment process including searching for a trailer within a specified area of image data that is less than a total field of the image data in directions corresponding with both a longitudinal distance between the vehicle and the trailer and a lateral direction perpendicular to the longitudinal distance, presenting an indication to a driver of the vehicle to reposition the vehicle when the trailer is not identified within the specified area, and removing the indication when the trailer is identified within the specified area. The controller further executes an automated backing process upon identifying the trailer within the specified area, including identifying a coupler of the trailer and outputting a steering signal to the vehicle to cause the vehicle to steer to align a hitch ball of the vehicle with the coupler of the trailer during reversing.

Abstract: A method and system for characterizing an energy consumption indicator of an electric vehicle (EV) is provided. The method includes performing a cyclic energy consumption test on the EV to acquire a time-speed curve, a time-direct current (DC) energy consumption curve, and a total alternating current (AC) energy consumption in the test cycle. A DC energy consumption rate and an AC energy consumption rate of the EV is determined in each of test sub-cycles. A driving feature is determined in each of the test sub-cycles and a normalized driving feature is determined in each of the test sub-cycles according to the driving feature in each of the test sub-cycles and a base driving feature. A DC energy consumption indicator and an AC energy consumption indicator of the EV are extracted according to DC energy consumption rates, AC energy consumption rates and normalized driving features of the EV in all test sub-cycles.

Abstract: A system for assisting in aligning a vehicle for hitching with a trailer includes a controller that identifies at least one of the trailer or a coupling feature of the trailer within image data and determines that the at least one of the trailer or the coupling feature is outside of a target position area relative to the vehicle and outputs an instruction for movement of the vehicle determined to position the one of the trailer or the coupling feature within the target position area in response to identifying at least one indication of a user difficulty in positioning the one of the trailer or the coupling feature within the target position area.

Abstract: A system for assisting in aligning a vehicle for hitching with a trailer includes a first camera and a second camera and outputting image data to the rear of the vehicle and a controller identifying at least one of the trailer or a coupling feature of the trailer within the image data and assigning a trailer type to the trailer identified within the image data, the trailer type including a first trailer type and a second trailer type. The controller further causes a portion of the image data to be presented on a display within the vehicle, the portion of the image data corresponding with the first camera in response to the trailer being assigned the first trailer type and corresponding with the second camera in response to the trailer being assigned the second trailer type.

Abstract: A system for assisting in aligning a vehicle for hitching with a trailer includes an imager outputting image data of a field of view to the rear of the vehicle and a controller identifying at least one of a trailer or a coupler of the trailer within the image data. The controller further determines that the at least one of the trailer or the coupler is outside of a specified area relative to the vehicle and outputs an instruction for movement of the vehicle determined to position the one of the trailer or the coupler within the specified area. Upon determining that the at least one of the coupler and the trailer is within the specified area, the coupler outputs a steering signal to the vehicle to cause the vehicle to steer to align a hitch ball of the vehicle with the coupler.

Abstract: A vehicle hitching assistance system includes a controller acquiring image data from the vehicle and identifying a plurality of trailers within in a specified area of the image data. The specified area is less than a total field of the image data and corresponds at least with left and right steering angle limits of the vehicle. The controller further receives a selection of a subject trailer of the plurality of trailers identified within the specified area, identifies a coupler of the subject trailer, and outputs a steering signal to the vehicle to cause the vehicle to steer to align a hitch ball of the vehicle with the coupler of the subject trailer.

Abstract: The disclosure describes systems and methods including a mobile device for remotely controlling the movement of a vehicle and trailer. The mobile device provides an intuitive interface for controlling the movement of the vehicle and trailer by changing the orientation of a vehicle graphic (e.g., of the vehicle and trailer) according to a position of the mobile device around a periphery of the vehicle and trailer. This allows the user to walk around the vehicle and trailer to determine a best position from which to control the vehicle and trailer depending on a given situation without losing the intuitiveness of the user interface.