Abstract: The present application relates to an assay method using affinity crosslinking of DNA-linked ligands to proteins to enable small molecule screening and determination of apparent affinity constants of ligands to the proteins. This method has been applied to determine 96 compounds' dissociation constants to a protein target simultaneously, and directly determine a compound's IC50 against five protein targets concurrently in crude cell lysates. Additionally, this approach was used to screen a Library of Pharmacologically Active Compounds (LOPAC) library against dihydrofolate reductase (eDHFR), enabling the discovery of a novel eDHFR inhibitor (IC50=7.9 ?M). An assay kit and the method of uses are within the scope of this disclosure.

Abstract: In the method, a terminal device display a first interface including a taken picture; collect a plurality of frames of images corresponding target object, and obtain an association relationship between the plurality of frames of images; and obtain a three-dimensional model corresponding to the target object based on the plurality of frames of images and the association relationship between the plurality of frames of images, and display the three-dimensional model. When the plurality of frames of images are collected, a first virtual bounding body including a plurality of patches is displayed. When the terminal device is in a first pose, the terminal device collects a first image, and changes a display effect of a patch corresponding to the first image. When the terminal device is in a second pose, the terminal device collects a second image, and changes a display effect of a patch corresponding to the second image.

Abstract: A luminaire comprises an outer housing, a main circuit board mounted inside the outer housing, a luminaire driver mounted on the main circuit board and a light source attached to the outer housing from the outside of the outer housing. The light source comprises a first push fit connector portion which extends into the main housing and the main circuit board comprises a second push fit connector portion which engages with the first push fit connector portion when the main circuit board, outer housing and light source are assembled to provide an electrical connection between the main circuit board and the light source.

Abstract: In the method, a terminal device display a first interface including a taken picture; collect a plurality of frames of images corresponding target object, and obtain an association relationship between the plurality of frames of images; and obtain a three-dimensional model corresponding to the target object based on the plurality of frames of images and the association relationship between the plurality of frames of images, and display the three-dimensional model. When the plurality of frames of images are collected, a first virtual bounding body including a plurality of patches is displayed. When the terminal device is in a first pose, the terminal device collects a first image, and changes a display effect of a patch corresponding to the first image. When the terminal device is in a second pose, the terminal device collects a second image, and changes a display effect of a patch corresponding to the second image.

Abstract: A solid-state drive configuration method includes: obtaining a data type corresponding to a stream supported by a solid-state drive, where the stream corresponds to a partition of the solid-state drive; determining, based on the data type corresponding to the stream, a garbage collection policy corresponding to the stream; and sending the garbage collection policy corresponding to the stream to the solid-state drive. In this way, during subsequent garbage collection, garbage collection may be performed on a partition according to a garbage collection policy corresponding to the partition, fully considering that data may be updated and invalid.

Abstract: A three-dimensional (3D) model generation method includes obtaining, based on a missing region of an initial 3D model of a target object, a camera pose sequence for performing photographing on the target object, where the initial 3D model is obtained by performing 3D modeling based on a first image sequence, and the first image sequence is obtained by performing photographing around the target object; obtaining a second image sequence, where the second image sequence is an image sequence obtained by performing photographing on the target object based on the camera pose sequence; and filling the missing region of the initial 3D model based on the second image sequence to generate a target 3D model.

Abstract: An imaging device is provided. The imaging device includes: one or more imaging sources; and a plurality of detectors combined by joining, the plurality of detectors being configured to receive one or more imaging beams emitted by the one or more imaging sources.

Abstract: The present invention relates to the technical field of communications, and in particular relates to an array antenna apparatus and a preparation method therefor, and an electronic device. The array antenna apparatus includes a first substrate and a second substrate which are provided from top to bottom. A first antenna is provided on the first substrate, a second antenna is provided on the second substrate, the first antenna is provided with a plurality of array elements arranged in an array, the second antenna is provided with a plurality of array elements arranged in an array, and the projections, on the second substrate, of all the array elements of the first antenna and all the array elements of the second antenna do not completely coincide. The present invention has the advantages of low sidelobe, large bandwidth, and multiple beams, etc.

Abstract: The present disclosure is related to systems and methods for radiation. The method may include obtaining a plurality of reference images of a target of a subject and reference physiological motion information of the subject. The plurality of reference images and the reference physiological motion information may be acquired in a radiation period. The method may include establishing a correlation model based on the plurality of reference images and the reference physiological motion information. The method may include monitoring real-time motion information of the target based on the correlation model during a radiation operation performed during the radiation period.

Abstract: A gas sensor probe having multipoint reflection rectangular absorption cell, a VCSEL laser emitter and a detection device. The probe comprises: an upper cover plate, the surface of the upper cover plate being provided with gas diffusion holes, and a metal filtering screen being provided above the gas diffusion holes; a lower cover plate located under the upper cover plate and detachably connected to the upper cover plate, and an electric wire through hole being formed in the bottom of the lower cover plate; a light path module located in an internal space defined by the upper cover plate and the lower cover plate and used for modulating the laser emitter and collecting a detection signal; and an electronic processing circuit board located in the internal space defined by the upper cover plate and the lower cover plate, located below the light path module, electrically connected to the light path module, and used for processing the signal generated from the light path module.

Abstract: The present disclosure is related to systems and methods for radiation. The method may include obtaining a plurality of reference images of a target of a subject and reference physiological motion information of the subject. The plurality of reference images and the reference physiological motion information may be acquired in a radiation period. The method may include establishing a correlation model based on the plurality of reference images and the reference physiological motion information. The method may include monitoring real-time motion information of the target based on the correlation model during a radiation operation performed during the radiation period.

Abstract: In the method, a terminal device display a first interface including a taken picture; collect a plurality of frames of images corresponding target object, and obtain an association relationship between the plurality of frames of images; and obtain a three-dimensional model corresponding to the target object based on the plurality of frames of images and the association relationship between the plurality of frames of images, and display the three-dimensional model. When the plurality of frames of images are collected, a first virtual bounding body including a plurality of patches is displayed. When the terminal device is in a first pose, the terminal device collects a first image, and changes a display effect of a patch corresponding to the first image. When the terminal device is in a second pose, the terminal device collects a second image, and changes a display effect of a patch corresponding to the second image.

Abstract: A stem removal device for a cigarette making process is disclosed, including a feeding unit (N1), a flexible air sorting unit (N2), a pure tobacco collection unit (N3), a tobacco conveying unit (N4), a coarse stem removal unit (N5) and a fine stem removal unit (N6). A method for removing the stems during the cigarette making process using the stem removal device is also disclosed.

Abstract: A device for removing unwanted objects from cut tobacco in a cut tobacco production line is disclosed, which includes: a raw cut tobacco feeding and conveying unit (N1), a heavy unwanted object removal unit (N2), a cut tobacco dispersion and recovery unit (N3), a moderate unwanted object removal unit (N4), a cut tobacco humidification unit (N5) and a light unwanted object removal unit (N6). An unwanted object removal method using the cut tobacco unwanted object removal device is also disclosed. The device and method of the disclosure can effectively remove unwanted objects from cut tobacco.

Abstract: A radiation therapy system is disclosed. The radiation therapy system includes a gantry, a first radiation source, and a second radiation source. The gantry is configured to have a cavity extending in a direction along a rotation axis, and the cavity is configured to house a target object. The first radiation source is mounted on the gantry, and configured to emit a treatment beam to a treatment area of the target object. The second radiation source is mounted on the gantry, and configured to emit an imaging beam to an imaging area of the target object. The treatment area partially overlaps the imaging area. A rotation plane of the first radiation source and a rotation plane of the second radiation source are distributed in a direction along the rotation axis.

Abstract: The disclosure relates to a switched capacitor converter (SCC) with gate driving circuits for limiting currents provided by switching field effect transistors. Embodiments disclosed include an SCC with gate driver curcuits providing gate voltage signals to power FETs, each gate driver circuit comprising first and second gate driver modules and configured to operate in: a first mode in which the first gate driver module provides a gate voltage signal to a power FET that switches between first and second voltage rails by operation of first and second switches connected between the pair of voltage rails; and a second mode in which, in reponse to enabling of a current limit switching signal, the first gate driver module disables switching of one of the first and second switches and the second gate driver module operates to limit a current provided to the power FET.

Abstract: A non-isolated LED driver has a converter which delivers first and second outputs. A sense circuit is coupled to both the first output and the second output, between the converter and an LED unit. The currents at the first output and the second output are compared to obtain a difference therebetween, and a leakage fault is determined based on an alternating current component of the difference. This avoids the need for an isolated driver, by instead detecting a leakage fault and then taking appropriate safety actions.

Abstract: A control circuit for controlling a power converter can include: a constant voltage output module, a constant current output module, and a power stage circuit; and where the control circuit is configured to select one of a first feedback signal representative of output information of the constant current output module, and a second feedback signal representative of output information of the constant voltage output module as a feedback input signal based on operation states of the constant current output module and the constant voltage output module, in order to control a switching state of a power switch of the power stage circuit.

Abstract: The present disclosure is related to systems and methods for radiation. The method may include obtaining a plurality of reference images of a target of a subject and reference physiological motion information of the subject. The plurality of reference images and the reference physiological motion information may be acquired in a radiation period. The method may include establishing a correlation model based on the plurality of reference images and the reference physiological motion information. The method may include monitoring real-time motion information of the target based on the correlation model during a radiation operation performed during the radiation period.

Abstract: A gas sensor probe having multipoint reflection rectangular absorption cell, a VCSEL laser emitter and a detection device. The probe comprises: an upper cover plate, the surface of the upper cover plate being provided with gas diffusion holes, and a metal filtering screen being provided above the gas diffusion holes; a lower cover plate located under the upper cover plate and detachably connected to the upper cover plate, and an electric wire through hole being formed in the bottom of the lower cover plate; a light path module located in an internal space defined by the upper cover plate and the lower cover plate and used for modulating the laser emitter and collecting a detection signal; and an electronic processing circuit board located in the internal space defined by the upper cover plate and the lower cover plate, located below the light path module, electrically connected to the light path module, and used for processing the signal generated from the light path module.