Abstract: Provided are a bispecific antibody or an antigen-binding fragment thereof, a nucleic acid encoding the same, a cell comprising the nucleic acid, a composition comprising the bispecific antibody or antigen-binding fragment thereof, the nucleic acid and/or the cell, and related applications of the bispecific antibody or antigen-binding fragment thereof in the treatment of cancer.

Abstract: A bistable weak PUF circuit with an autonomous stability screening function is provided. The bistable weak PUF circuit includes a decoder, a timing circuit, and a PUF core circuit is provided. The PUF core circuit realizes stable bit screening by connecting two screening levels. When the two screening levels connected to the PUF core circuit are equal, the PUF core circuit generates a W-bit original PUF response in one clock cycle under the control of an m-bit word line level signal output thereto by the decoder. Then, the m-bit word line level signal received by the PUF core circuit is kept unchanged, one of the two screening levels connected to the PUF core circuit is kept unchanged, and the other is reduced by a certain amplitude, and two W-bit screened PUF responses are obtained after the screening levels are exchanged.

Abstract: Aspects relate to carrier aggregation. Selection of an uplink component carrier for carrier aggregation may be flexible in the sense that the frequency band of the uplink component carrier need not be one of the frequency bands allocated for the downlink component carriers. Thus, in some aspects, an uplink component carrier may be decoupled from (e.g., independent of) the downlink carriers. A decision of whether to implement flexible uplink component carrier selection may be based on network traffic (e.g., particular traffic use cases). As one example, the data throughput requirement for downlink traffic may be relatively high, but the component carriers selected for the downlink traffic to provide this throughput might not provide a desired level of service for the uplink traffic. Thus, one or more component carrier bands selected for the uplink traffic may be different from any of the component carrier bands selected for the downlink traffic.

Abstract: A wireless communication in a user device includes configuring a plurality of transmission chains with a plurality of carriers; and uploading data in a time-division duplexed (TDD) or frequency division duplex (FDD) transmission through the plurality of transmission chains. In some embodiments, two transmission chains and two carriers are used for carrier aggregation uplink of data. An apparatus may include a plurality of transmit chains, each of the plurality of transmit chains providing transmission of data using TDD or FDD transmissions; a plurality of antennas, each of the antennas providing transmission of data from one of the plurality of transmit chains into one of a plurality of carriers; and a time-division multiplexed (TDM) switch coupled between the plurality of transmit chains and the plurality of antennas such that each of the plurality of transmit chains transmits data on one of the plurality of carriers.

Abstract: Provided are a bispecific antibody or an antigen-binding fragment thereof, a nucleic acid encoding the same, a cell comprising the nucleic acid, a composition comprising the bispecific antibody or antigen-binding fragment thereof, the nucleic acid and/or the cell, and related applications of the bispecific antibody or antigen-binding fragment thereof in the treatment of cancer.

Abstract: This disclosure relates to a manufacture method of a bushing, a bushing and an excavator to alleviate the problems of insufficient lubricity and wear resistance of the bushing. The bushing includes an inner ring and an outer ring. The manufacture method of the bushing includes the following steps: grinding a first mixed powder containing Fe, Al, Ti, Cr and V, nitriding the ground first mixed powder to form a nitrogen-rich stable compound powder, and then carrying out molding by pressing and sintering the nitrogen-rich stable compound powder to form the outer ring; grinding a second mixed powder containing Fe and Mo, sulfurizing the ground second mixed powder to form a sulfurized powder containing FeS and MoS2, and carrying out molding by pressing the sulfurized powder to form the inner ring; and placing the inner ring in the outer ring and carrying out sintering to obtain the bushing.

Abstract: Effector-deficient anti-CD32a monoclonal antibodies are encompassed, as are method and uses for treating CD32a-mediated diseases and disorders, including, thrombocytopenia, allergy, hemostatic disorders, immune, inflammatory, and autoimmune disorders.

Abstract: Methods, systems, and devices for wireless communications are described. A base station may receive a capability message from a user equipment (UE) based on a number of receive antennas exceeding a number of transmit antennas at the UE. The base station may configure the UE with a mapping between sounding reference signal (SRS) resources and bit sequences, or SRS resource indices (SRIs), based on the capability message. The base station may transmit a control message including one or more SRIs indicating respective SRS resources. The UE may use the one or more SRIs included in a control message from the base station to select respective SRS resources from a resource set. Once the UE selects one or more SRS resources, the UE may transmit one or more SRSs in the SRS resources.

Abstract: Aspects of the present disclosure provide apparatus, methods, processing systems, and computer readable mediums for configuring, based on capability of the user equipment (UE) in switching among multiple component carriers (CCs), the UEs for communications with multiple activated CCs. For example, the network may configure the UE with a number of activated CCs that exceeds a number of CCs supported by the UE for simultaneous connections, such that the UE quickly switches among the activated CCs. The UE can thus effectively utilize more operating bands than the number allowed for simultaneous connections using inter-band carrier aggregations.

Abstract: The present invention relates to an antibody comprising a GPRC5D-binding domain and use thereof. A GPRC5D×CD3 bispecific antibody has a strong killing effect on low-expressing cells and is gentler in activating T cells. A GPRC5D×BCMA×CD3 trispecific antibody can kill BCMA+ cells and GPRC5D+ cells at the same time. The present invention is conducive to overcoming drug resistance caused by single targets and producing more profound and lasting anti-tumor effects in clinical applications.

Abstract: The disclosure relates to compounds of Formula (I) and pharmaceutically acceptable salts thereof, wherein X1, X2, and Y are as defined in the description; to their use in medicine; to compositions containing them; to processes for their preparation; and to intermediates used in such processes. The compounds of Formula (I) may modulate the activity of antigens of interest and may be useful in inducing or enhancing an immune response against diseases, disorders and conditions mediated by antigens of interest. In a particular embodiment, the compounds of Formula (I) may be useful as a component of a liposomal adjuvant formulation.

Abstract: A data processing method is provided and may be applied to the field of artificial intelligence. The method includes: obtaining a first prompt, where the first prompt includes attribute information of a user, and the first prompt indicates to infer a preference of the user based on the attribute information of the user; obtaining first information based on the first prompt by using a large language model LLM; and predicting, based on the first information and second information by using a recommendation model, information about an operation performed by the user on an item, where the second information is attribute information of the item.

Abstract: A method of ethanol conversion to higher carbon compounds is provided. The method includes feeding a reactant to a reactor, the reactant including ethanol. The reactant may further include water in the form of steam. The reactant is introduced to a perovskite catalyst in the reactor. The perovskite catalyst promotes the formation of the higher carbon compounds from ethanol, and may be in the form of a powder or thin film. The perovskite catalyst has the formula ABO3, wherein A is one or more selected from a group consisting of La and Sr, and wherein B is one or more selected from a group consisting of Mn, Ca, Fe, and Co. The perovskite catalyst particularly may be La0.7Sr0.3MnO3. The obtained higher carbon compounds may include at least one of acetone and crotonaldehyde.

Abstract: This disclosure provides systems, methods, and devices for wireless communication that support use of a supplemental uplink (SUL) carrier. In a first aspect, a user equipment (UE) is configured to receive, from a base station, a carrier set configuration indicating multiple uplink (UL) carriers. The multiple UL carriers include multiple SUL carriers and a non-SUL carrier. The UE is further configured to select one or more carriers of the multiple UL carriers, and transmit a channel on each carrier of the one or more carriers. Other aspects and features are also claimed and described.

Abstract: A strong PUF circuit with good stability and anti-ML attack capacity is provided. The strong PUF circuit includes n delay modules, n?1 interconnection modules, an arbiter array and an XOR gate, wherein n is an integer greater than or equal to 1, each delay module is implemented based on a bias source structure, and the number of transmission paths of input signals can be increased by means of the characteristics of the bias source structure of the delay module to realize a diversity of transmission, thus realizing a highly complex and unpredictable challenge-response mapping relation without multiple strong PUFs. The transmission characteristics (transmission paths) of the input signals can be further obfuscated by means of the interconnection modules. Only one XOR gate is used for generating response outputs to further improve the stability.

Abstract: An isolation valve system includes a well string having an isolation valve including a rotatable ball for rotation about a fixed axis. The isolation valve has an extension mandrel and a connecting mandrel disposed above the rotatable ball. The isolation valve has a debris sleeve designed to push debris inward and upward in the extension mandrel accumulated above the rotatable ball when the ball is rotated to alleviate the friction force of the debris acting on the rotating ball.