Patents by Inventor Bo F. Oberg

Bo F. Oberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Postexposure prevention of HIV infection or seroconversion
    Patent number: 5612319
    Abstract: A method of preventing the establishment of HIV infection and/or HIV seroconversion in a human or simian comprising the administration of an effective amount of the compound 1-[2',3'-dideoxy-3'C-(hydroxymethyl)-.beta.-D-erythropentofuranosyl]-cytos ine having the following formula: ##STR1## or a pharmaceutically acceptable salt thereof, after exposure of said human or simian to HIV.
    Type: Grant
    Filed: May 31, 1994
    Date of Patent: March 18, 1997
    Assignee: Medivir AB
    Inventor: Bo F. Oberg
  • Derivatives of purine, process for their preparation and a pharmaceutical preparation
    Patent number: 5565461
    Abstract: The present invention is directed to a method of treating an HIV infection in a host in need of such treatment which comprises administering an effective anti-HIV amount of a compound having the formula ##STR1## wherein: R.sup.1 is hydrogen, hydroxyl;R.sup.2 is amino;R.sup.3 and R.sup.4 are independently selected from hydroxyl or an ester residue of said hydroxyl group derived from R.sup.6 COOH, wherein R.sup.6 is hydrogen, or C.sub.1 -C.sub.3 alkyl; and n is 1; or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: April 3, 1995
    Date of Patent: October 15, 1996
    Assignee: Medivir AB
    Inventors: Bj orn G. Lindborg, Roelf Datema, Karl N. G. Johansson, Bo F. Oberg
  • Anti-retroviral activity of 2',3'-dideoxy-3'-fluoronucleosides
    Patent number: 5446029
    Abstract: Use of a compound of the formula ##STR1## wherein Base is thymine, Cytosine, adenine or guanine, or a physiologically acceptable salt thereof, for therapeutic treatment of hepatitis B virus infections and to a method for such treatment.
    Type: Grant
    Filed: September 9, 1993
    Date of Patent: August 29, 1995
    Assignee: Medivir AB
    Inventors: Bertil F. H. Eriksson, Karl N. G. Johansson, Goran B. Stening, Bo F. Oberg
  • .alpha. nucleoside compounds and a method for treating HBV using said compounds
    Patent number: 5409906
    Abstract: A compound of the formula ##STR1## wherein the radicals A, X, R.sup.1, R.sup.2 and R.sup.3 are defined as follows:A: ##STR2## X: (a) O (b) S(c) CH.sub.2R.sup.1 : H; alkyl containing 1-3 carbon atoms;--CH.dbd.CH.sub.2 ; --CH.dbd.CH--CH.sub.3 ; --CH.sub.2 --CH.dbd.CH.sub.2 ; ##STR3## --C.tbd.CH p1 R.sup.2 : H; or R.sup.2 constitutes together with R.sup.3 a carbon--carbon bondR.sup.3 : H; F; Cl; Br; I; N.sub.3 ; CN; C.tbd.CH; OH; OCH.sub.3 ; CH.sub.2 OH; and when R.sup.3 is F; Cl; Br; I; N.sub.3 ; CN; C.tbd.CH; OH; OCH.sub.3 or CH.sub.2 OH it may have either the cis-configuration or trans-configuration relative to the hydroxymetyl function at position 4', or R.sup.3 constitutes together with R.sup.2 a carbon--carbon bond, and therapeutically acceptable salts thereof, for use in therapy, in particular for the treatment of HIV virus infections.
    Type: Grant
    Filed: April 1, 1993
    Date of Patent: April 25, 1995
    Assignee: Medivir AB
    Inventors: Roelf Datema, Zsuzanna M. I. Kovacs, Karl N. G. Johansson, Bjorn Lindborg, Goran B. Stening, Bo. F. Oberg
  • Nucleosides and nucleotide analogues, pharmaceutical composition and processes for the preparation of the compounds
    Patent number: 5215970
    Abstract: A compound of the formula ##STR1## wherein the radicals A, X, R.sup.1, R.sup.2 and R.sup.3 are defined as follows: ##STR2## R.sup.2 : H; or R.sup.2 constitutes together with R.sup.3 with a carbon - carbon bondR.sup.3 : H; F; Cl; Br; I; N.sub.3 ; CN; C.tbd.CH; OH; OCH.sub.3 ; CH.sub.2 OH; and when R.sup.3 is F; Cl; Br; I; N.sub.3 ; CN; C.tbd.CH; OH; OCH.sub.3 or CH.sub.2 OH it may have either the cis-configuration or trans-configuration relative to the hydroxymethyl function at position 4', or R.sup.3 constitutes together with R.sup.2 a carbon - carbon bond, and therapeutically acceptable salts thereof, for use in therapy, in particular for the treatment of HIV infections.
    Type: Grant
    Filed: November 20, 1991
    Date of Patent: June 1, 1993
    Assignee: Medivir AB
    Inventors: Roelf Datema, Zsuzanna M. I. Kovacs, Karl N. G. Johansson, Bjorn G. Lindborg, Goran B. Stening, Bo F. Oberg