Abstract: NNA-derived specific adducts represent an integrated biomarker of exposure to thirdhand smoke (THS) as NNA is unique to THS. The NNA-dG covalent binding adduct could serve as such a biomarker, and play a role in identifying individuals exposed to THS, thus providing critical information for early detection and prevention.

Abstract: The present invention provides for a library or an array of two or more nucleic acids encoding portions of genes selected from a set of 27 genes which are useful for predicting lung cancer survival, and a method for predicting a subject's overall survival (OS) from a lung cancer using two or more genes selected from the set of 27 genes.

Abstract: Disclosed is use of a panel of gastric cancer (GC)-related genes in clinical applications. The present invention is based on a panel of 53 genes related to prognosis in GC and detection of their expression levels in clinical samples to calculate prognostic scores, so as to evaluate clinical prognosis of GC patients and its other applications. This score system is useful for assisting in treatment selection for GC patients and predicting the response to therapeutic intervention, to determine the degree of benefit of patients from chemotherapy and targeted therapy, thus avoiding overtreatment, reducing medical cost, and achieving personalized medicine. Accordingly, a 53-gene expression assay kit is designed and developed according to this system and different detection technology platforms.

Abstract: NNA-derived specific adducts represent an integrated biomarker of exposure to thirdhand smoke (THS) as NNA is unique to THS. The NNA-dG covalent binding adduct could serve as such a biomarker, and play a role in identifying individuals exposed to THS, thus providing critical information for early detection and prevention.