Abstract: The present invention relates to the development of an L-arabinose isomerase variant from Thermotoga neapolitana DSM 5068, which is a kind of thermophile, on the basis of protein molecular modeling. Moreover, the present invention relates to a method of producing D-tagatose from D-galactose by using the enzyme or a microorganism of the genus Corynebacterium expressing the enzyme.

Abstract: Compounds of formula (I) are useful for inhibiting a proteasome in a cell. Compounds, pharmaceutical compositions and methods of use are provided herein.

Abstract: The present invention relates to a sweetener composition for alleviating diabetes, containing psicose and a slowly digestible or digestion-resistant polysaccharide as active ingredients, wherein diabetes alleviating effects and the quality of sweetness are enhanced.

Abstract: The present invention relates to a surface-treated substrate having excellent corrosion resistance and capable of developing color on the surface, and to a substrate surface treatment method for same. The surface-treated substrate, according to the present invention, comprises a coating having a uniform thickness on a metal matrix, thereby improving corrosion resistance and evenly developing color on the surface. Also, by comprising a wavelength conversion layer and a top coat, in order, on top of the coating, the advantage of improving scratch resistance and durability of the substrate without discoloring of the achieved color can be provided.

Abstract: This color-treated base material, which comprises a matrix comprising magnesium, a film formed on the matrix and containing a compound represented by chemical formula 1, and a wavelength conversion layer formed on the film, can improve the durability of the base material while maintaining the unique metal texture and gloss of the base material and can uniformly realize various colors, such as blue and green, including an achromatic color such as black, on the surface of the base material and thus can be usefully used in the fields of building exterior materials, automobile interiors, and particularly electrical/electronic component materials, such as mobile product frames, in which a metal material is used.

Abstract: A shift control apparatus of a manual transmission is disclosed. The shift control apparatus includes: a shift lever including a rod; a shift lock limiting the movement of the rod; and a controller which compares a speed of a vehicle with a predetermined critical speed of a predetermined gear and controls the shift lock. When the speed of the vehicle is greater than the critical speed, the controller controls the shift lock to be located on a shift path of the predetermined gear, and then limits the movement of the rod in a shift direction of the predetermined gear.

Abstract: A method for producing D-galactose from a dissolved solution of dried whey permeate or a liquid whey permeate is disclosed. The method comprises: removing non-sugar insoluble materials from the dissolved solution of dried whey permeate or the liquid whey permeate; removing protein from the dissolved solution of dried whey permeate or the liquid whey permeate from which non-sugar solid precipitates are removed; and removing ash, salts or both from the dissolved solution of dried whey permeate or the liquid whey permeate from which the proteins are removed. Another method for producing D-tagatose is disclosed. The other method comprises isomerizing D-galactose produced by the foregoing method.

Abstract: A method for producing tagatose comprises: a) performing epimerization of fructose using hexuronate C4-epimerase to obtain an epimerized product comprising tagatose; b) purifying the epimerized product; and c) crystallizing the purified epimerized product. The hexuronate C4-epimerase is an enzyme derived from Thermotoga maritima, Thermotoga neapolitana, Thermotoga thermarum or mutants thereof. The hexuronate C4-epimerase is produced from strains Escherichia. coli, Corynebacterum glutamicum, Aspergillus oryzae, or Bacillus subtilis.

Abstract: A method for acquiring a PET image with ultra high resolution using movement of a PET device is provided. In the related art, there is a limit in lowering of the resolution below a half (d/2) of the width of a detector. According to the provided method, an image with ultra high resolution, which can jump over the limit, can be acquired. Further, since utilization of larger detectors becomes possible without a loss of the resolution, the sensitivity of the PET can be improved, and thus an image of higher quality can be acquired.

Abstract: Provided is a continuous coating apparatus which can supply a liquid coating material (a molten metal) to a levitation-heating space through various paths, and can easily control a supply flow rate of the liquid coating material, and has a simplified structure. The continuous coating apparatus includes: a vacuum chamber unit through which a coating target passes; a levitation-heating unit disposed in the vacuum chamber unit and generating an evaporation vapor by vaporizing a supplied coating material; and a liquid coating material supply unit connected so that a liquid coating material is supplied to at least one of an upper portion and a lower portion of the levitation-heating unit, and communicating with the outside of the vacuum chamber unit.

Abstract: The present invention relates to an in-situ method for preparing rebaudioside A from sucrose and stevioside by sucrose synthase and glycosyltransferase.

Abstract: The present invention relates to a D-psicose 3-epimerase variant with improved thermostability by substituting an amino acid at a specific position of an amino acid sequence of a wild type D-psicose 3-epimerase. Further, the present invention provides a recombinant expression vector including a gene of the D-psicose 3-epimerase variant, and a recombinant strain transformed with the recombinant expression vector. Furthermore, the present invention provides an immobilized reactor prepared using the D-psicose 3-epimerase variant or the recombinant strain, and a method of continuously producing D-psicose using the immobilized reactor.

Abstract: The present invention relates to a method for tracking the motion of a subject in real time and for correcting a medical image. The method includes the steps of: (a) a motion detection module outputting real-time motion information of a subject; (b) a motion calculation module receiving and analyzing the real-time motion information, transforming the analyzed result into triaxial motion parameters, and outputting the triaxial motion parameters; (c) a driving module driving a driving motor in response to the triaxial motion parameters; and (d) a medical image data acquisition module moving by as much as the subject moves in response to the driving of the driving motor. According to the present invention, medical image data can be acquired as if a subject has not moved during imaging by calculating the triaxial motion parameters of a subject through motion information acquired from the motion detection module and moving the medical image data acquisition module according to the triaxial motion parameters.

Abstract: The present invention relates to an environmentally friendly, simple and economic process for producing xylose. The process comprises the steps of: a) countercurrently extracting tropical fruit biomass by hydrolysis with sulfuric acid to obtain a high-concentration xylose extract; b) adjusting the extract to a pH of 1.5-2.5 and decolorizing and filtering the pH-adjusted extract; c) desalting the filtrate in an electrodialysis device; and d) recycling a waste sulfuric acid solution recovered from step c), to step a), and concentrating and directly recovering the desalted filtrate to obtain xylose crystals.

Abstract: An array substrate of a liquid crystal display device and a method of fabricating the array substrate. A gate electrode of a thin film transistor of the array substrate is formed. The gate electrode has an edge region surrounding an interior region of the gate electrode and the edge region of the gate electrode is thicker than the interior region of the gate electrode. A semiconductor layer is formed over the gate electrode. A source electrode and a drain electrode of the thin film transistor are formed that define a channel region in the semiconductor layer. The channel region is located over the interior region of the gate electrode. Additionally, the gate electrode may be formed with a half-tone mask that results in the edge region of the gate electrode being thicker than the interior region of the gate electrode.

Abstract: Disclosed are a preparation method of a steel product capable of local reinforcement using laser heat treatment, and a heat hardened steel used in the method. According to the present invention, the preparation method of a steel part comprises the following steps: (a) preparing a material comprising 0.1-0.5 wt % of C, 0.1-0.5 wt % of Si, 0.5-3.0 wt % of Mn, 0.1 wt % or less of P, 0.05 wt % or less of S, 0.01-1.0 wt % of Cr, 0.1 wt % or less of Al, 0.2 wt % or less of Ti, 0.0005-0.08 wt % of B, and the balance of Fe and inevitable impurities; (b) preparing a formed product by forming the material into a predetermined shape; and (c) locally reinforcing the high strength portion by carrying out laser heat treatment on a portion requiring high strength at the formed product.

Abstract: An array substrate of a liquid crystal display device and a method of fabricating the array substrate. A gate electrode of a thin film transistor of the array substrate is formed. The gate electrode has an edge region surrounding an interior region of the gate electrode and the edge region of the gate electrode is thicker than the interior region of the gate electrode. A semiconductor layer is formed over the gate electrode. A source electrode and a drain electrode of the thin film transistor are formed that define a channel region in the semiconductor layer. The channel region is located over the interior region of the gate electrode. Additionally, the gate electrode may be formed with a half-tone mask that results in the edge region of the gate electrode being thicker than the interior region of the gate electrode.

Abstract: Disclosed is a lighting device for a street lamp, of which a structure is improved such that the diffusion degree of light may be effectively controlled by improving the directivity of a luminous element. To this end, the lighting device for a street lamp includes: a base member which is formed at an upper side of a street lamp body arranged above a ground surface; a plurality of luminous element units, which are comprised of at least one luminous element, and are arranged on the bottom surface of the base member; and a plurality of reflection units, which are arranged to be adjacent to the luminous element units, and are arranged mutually isolated from each other by a predetermined distance on the bottom surface of the base member to diffuse light radiated from the luminous element units in multiple directions.

Abstract: The present invention relates to an apparatus for preparing enzyme-immobilized beads used for preparation of tagatose, and a method for preparing enzyme-immobilized beads using the same. More specifically, the present invention relates to an apparatus for preparing enzyme-immobilized beads, comprising a nozzle with an inside diameter of 0.1-1 mm having a cylindrical lower end and comprising a cut-type liquid outlet (cut perpendicularly to the vertical axis of the nozzle) formed at the lower end, and a method for preparing enzyme-immobilized beads using the same.

Abstract: An array substrate of a liquid crystal display device and a method of fabricating the array substrate. A gate electrode of a thin film transistor of the array substrate is formed. The gate electrode has an edge region surrounding an interior region of the gate electrode and the edge region of the gate electrode is thicker than the interior region of the gate electrode. A semiconductor layer is formed over the gate electrode. A source electrode and a drain electrode of the thin film transistor are formed that define a channel region in the semiconductor layer. The channel region is located over the interior region of the gate electrode. Additionally, the gate electrode may be formed with a half-tone mask that results in the edge region of the gate electrode being thicker than the interior region of the gate electrode.