Abstract: The present invention relates to an antigen-binding molecule comprising a heavy chain variable region comprising a heavy-chain complementarity-determining region 1 (HCDR1) comprising an amino acid sequence represented by Sequence No. 1, an HCDR2 comprising an amino acid sequence represented by Sequence No. 2, and an HCDR3 comprising an amino acid sequence represented by Sequence No. 3; a light-chain variable region comprising a light-chain complementarity-determining region 1 (LCDR1) comprising an amino acid sequence represented by Sequence No. 4, an LCDR2 comprising an amino acid sequence represented by Sequence No. 5, and an LCDR3 comprising an amino acid sequence represented by Sequence No. 6; wherein the antigen-binding molecule is a T cell receptor (TCR); and to a cell line expressing the same.

Abstract: A composition according to the present invention is capable of inhibiting the growth of cancer cells and cancer stem cells, and also is capable of very effectively inhibiting the metastasis of cancer cells to other tissues. Thus, the composition may be very effectively used not only for the prevention, amelioration or treatment of cancer, but also for the inhibition of cancer metastasis.

Abstract: The present disclosure provides a novel biphenyl derivative compound or a pharmaceutically acceptable salt thereof. The biphenyl derivative compound or pharmaceutically acceptable salt thereof according to the present disclosure is a compound that increases Nm23-H1/NDPK activity and can inhibit cancer metastasis and growth. Thus, it exhibits excellent effects not only on the prevention, alleviation and treatment of cancer, but also on the suppression of cancer metastasis.

Abstract: A user terminal according to an embodiment may include a processor configured to: based on accessing an instant messaging server with a user account and the user account being a general account, display a general interface for a plurality of services provided to the general account; and based on the user account being a protected account, display a protected interface in which at least some of the plurality of services provided to the general account is restricted.

Abstract: A magnetic field measuring apparatus according to an example embodiment includes: an external container; an internal container storing a liquid refrigerant, disposed inside the external container, and including a neck portion having a first diameter and a body portion having a second diameter greater than the first diameter, wherein a space between the internal container and the external container is maintained in a vacuum state; a SQUID sensor module mounting plate disposed below the internal container; a plurality of SQUID sensor modules mounted below the SQUID sensor module mounting plate; and a 4K heat shielding portion formed of a conductive mesh disposed to surround the SQUID sensor module mounting plate and the plurality of SQUID sensor modules.

Abstract: The present invention relates to: a disubstituted adamantyl derivative or a pharmaceutically acceptable salt thereof, and an anticancer pharmaceutical composition and a kit containing same as an active ingredient. The disubstituted adamantyl derivative according to the present invention suppresses the growth of cancer cells by targeting mitochondria ETC complex I and damaging the metabolism of cancer cells, and thus can be useful as an anticancer pharmaceutical composition that is a powerful therapeutic agent for cancer dependent on oxidative phosphorylation for producing ATP.

Abstract: A method and a user terminal for providing contents to a user, and a method and a server for providing contents to a user terminal. The method for providing contents to a user includes: displaying, by a user terminal, a first list including a first content belonging to a first set and a second content belonging to a second set different from the first set in a first region on a chat room screen; when a user's interaction with the first content is received, displaying, by the user terminal, a first interface for requesting contents in the first set; and when a user's interaction with the first interface is received, displaying, by the user terminal, an icon indicative of the first set on the screen and a second list including at least one content belonging to the first set in the first region.

Abstract: A method and a user terminal for providing contents to a user, and a method and a server for providing contents to a user terminal. The method for providing contents to a user includes: displaying, by a user terminal, a first list including a first content belonging to a first set and a second content belonging to a second set different from the first set in a first region on a chat room screen; when a user's interaction with the first content is received, displaying, by the user terminal, a first interface for requesting contents in the first set; and when a user's interaction with the first interface is received, displaying, by the user terminal, an icon indicative of the first set on the screen and a second list including at least one content belonging to the first set in the first region.

Abstract: Provided is a content recommendation method. The content recommendation method includes: receiving, by a user terminal, text information from a user through a text input window of a chatting room, outputting, by the user terminal, a first content set including at least a part of contents related to keyword information to be mapped to the text information, outputting, by the user terminal, a first preview content for a first content included in the first content set, receiving, by the user terminal, an interaction from the user, and in response to the interaction, outputting, by the user terminal, a second preview content for a second content to replace the first preview content, wherein the second content is a content related to the keyword information.

Abstract: Provided are a method and server for providing a content list. The method and server for providing a content list includes: providing source content to a chat room, receiving a request for providing a content list related to the source content from a first terminal of a first member; providing at least one of a first content list including at least one keyword-related content selected from among the entire contents stored in the server based on a keyword of the source content and a second content list including at least one group-related content belonging to the same group as a group of the source content among the entire contents, receiving information on selection content selected by the first member among the contents included in the at least one content list, from the first terminal, and providing the selection content to the chat room.

Abstract: The present invention relates to a method for preventing or treating cancer comprising administering a Synaptotagmin 11 (SYT11) inhibitor to a subject, a method for diagnosing cancer comprising measuring an expression level of SYT11, and a method for screening a preparation for treating cancer.

Abstract: Disclosed are a mobile robot system including a server of creating and storing traveling information about moving space and a mobile robot of travelling on the moving space, wherein the mobile robot comprises a driving portion configured to move the mobile robot, a communication device configured to receive the traveling information from the server and a controller configured to control the driving portion based on the traveling information received from the communication device and wherein the server receives information about the moving space from at least one external robot, and creates the traveling information based on the information about the moving space.

Abstract: The present disclosure provides a novel biphenyl derivative compound or a pharmaceutically acceptable salt thereof. The biphenyl derivative compound or pharmaceutically acceptable salt thereof according to the present disclosure is a compound that increases Nm23-H1/NDPK activity and can inhibit cancer metastasis and growth. Thus, it exhibits excellent effects not only on the prevention, alleviation and treatment of cancer, but also on the suppression of cancer metastasis.

Abstract: The present disclosure provides a novel biphenyl derivative compound, an optical isomer thereof or a pharmaceutically acceptable salt thereof. The biphenyl derivative compound, optical isomer thereof or pharmaceutically acceptable salt thereof according to the present disclosure may induce cancer cell death by damaging mitochondria and inducing ATP depletion in cells which are in a nutrient-starved state such as a glucose-starved state, which is the normal environment of cancer cells. In addition, it is an Nm23-H1/NDPK activity-increasing substance that may suppress cancer metastasis and growth. Thus, it exhibits excellent effects not only on the prevention, alleviation and treatment of cancer, but also on the suppression of cancer metastasis.

Abstract: The present invention relates to a pharmaceutical composition for treating cancer, containing cytochrome b5 reductase 3 (CYB5R3) protein as an active ingredient. Over-expression of CYB5R3 in cancer cells results in significant reduction of hypoxia-inducible factor-1? (HIF-1?) expression, which leads inhibition of cancer cells growth in vitro and in vivo. Thus, the CYB5R3 gene or protein of the present invention can be useful as an active ingredient of a pharmaceutical composition for treating cancer.

Abstract: A near-infrared-absorption white material, a method of manufacturing the same, and uses thereof. The near-infrared-absorption material includes copper pyrophosphate compound. The copper pyrophosphate compound has a brightness (CIE L*) value of 90 or more in a visible-ray region and is excellent in particle manufacturing properties, and a crystalline structure of the copper pyrophosphate compound is made chemically stable using a heat treatment at a high temperature. The copper pyrophosphate compound is represented by the following chemical formula: Cu2P2O7 or Cu2P2O7.XH2O (x=1-3).

Abstract: Disclosed are a robot cleaner, a refrigerator, a container transfer system, and a method of transferring and retrieving a container using the robot cleaner. The method of transferring a container include returning a robot cleaner to a position guide device installed at a refrigerator, mounting the robot cleaner on the position guide device, transferring, by the refrigerator, a container built in the refrigerator to mount the container on the robot cleaner, and moving the robot cleaner on which the container is mounted to a target position.

Abstract: The present invention relates to a compound exhibiting inhibitory activity of at least one of malate dehydrogenases I (MDH1) and malate dehydrogenases 2 (MDH2), and a pharmaceutical composition for preventing or treating cancer comprising the same as an active ingredient. The inventors of the present invention have experimentally confirmed that the compound exhibiting the MDH1 and/or MDH2 inhibitory activity has an inhibitory effect on mitochondrial respiration in cancer cells, an excellent inhibitory effect on cancer cell growth, etc. Thus, the compound of the present invention is expected to be effectively used as a pharmaceutical composition for treating cancer.

Abstract: An exhaust manifold may include a main body provided with a plurality of branching passages communicating with a vehicle engine and provided with a single passage communicating with an exhaust canister, the branching passages merging with the single passage; and a coating layer coated on an internal surface of the main body forming the branching passages and the single passage, the coating layer including an aerogel.

Abstract: A near-infrared-absorption white material, a method of manufacturing the same, and uses thereof. The near-infrared-absorption material includes copper pyrophosphate compound. The copper pyrophosphate compound has a brightness (CIE L*) value of 90 or more in a visible-ray region and is excellent in particle manufacturing properties, and a crystalline structure of the copper pyrophosphate compound is made chemically stable using a heat treatment at a high temperature. The copper pyrophosphate compound is represented by the following chemical formula: Cu2P2O7 or Cu2P2O7.XH2O (x=1?3).