Patents by Inventor Bo-Liang Deng

Bo-Liang Deng has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Oligomer-opioid agonist conjugates
    Patent number: 8575196
    Abstract: The invention provides compounds that are chemically modified by covalent attachment of a water-soluble oligomer. A compound of the invention, when administered by any of a number of administration routes, exhibits characteristics that are different from those of the compound not attached to the water-soluble oligomer.
    Type: Grant
    Filed: July 21, 2010
    Date of Patent: November 5, 2013
    Assignee: Nektar Therapeutics
    Inventors: Jennifer Riggs-Sauthier, Bo-Liang Deng, Timothy A. Riley
  • Oligomer-opioid agonist conjugates
    Patent number: 8569343
    Abstract: The invention provides compounds that are chemically modified by covalent attachment of a water-soluble oligomer. A compound of the invention, when administered by any of a number of administration routes, exhibits characteristics that are different from those of the compound not attached to the water-soluble oligomer.
    Type: Grant
    Filed: June 29, 2012
    Date of Patent: October 29, 2013
    Assignee: Nektar Therapeutics
    Inventors: Jennifer Riggs-Sauthier, Bo-Liang Deng, Timothy A. Riley
  • OLIGOMER CONJUGATES OF HETEROPENTACYCLIC NUCLEOSIDES
    Publication number: 20130261072
    Abstract: The invention provides small molecule drugs that are chemically modified by covalent attachment of a water-soluble oligomer
    Type: Application
    Filed: May 17, 2013
    Publication date: October 3, 2013
    Applicant: NEKTAR THERAPEUTICS
    Inventors: Bo-Liang Deng, Timothy A. Riley, Jennifer Riggs-Sauthier
  • Oligomer conjugates of heteropentacyclic nucleosides
    Patent number: 8466276
    Abstract: The invention provides small molecule drugs that are chemically modified by covalent attachment of a water-soluble oligomer.
    Type: Grant
    Filed: February 20, 2009
    Date of Patent: June 18, 2013
    Assignee: Nektar Therapeutics
    Inventors: Bo-Liang Deng, Timothy A. Riley, Jennifer Riggs-Sauthier
  • Oligomer-opioid agonist conjugates
    Patent number: 8440687
    Abstract: The invention provides compounds that are chemically modified by covalent attachment of a water-soluble oligomer. A compound of the invention, when administered by any of a number of administration routes, exhibits characteristics that are different from those of the compound not attached to the water-soluble oligomer.
    Type: Grant
    Filed: March 21, 2012
    Date of Patent: May 14, 2013
    Assignee: Nektar Therapeutics
    Inventors: Jennifer Riggs-Sauthier, Bo-Liang Deng, Timothy A. Riley
  • Oligomer-anticholinergic agent conjugates
    Patent number: 8389759
    Abstract: The invention provides anticholinergic agents that are chemically modified by covalent attachment of a water-soluble oligomer. A conjugate of the invention, when administered by any of a number of administration routes, exhibits characteristics that are different as compared to the characteristics of the anticholinergic agent not attached to the water-soluble oligomer.
    Type: Grant
    Filed: March 12, 2008
    Date of Patent: March 5, 2013
    Assignee: Nektar Therapeutics
    Inventors: Jennifer Riggs-Sauthier, Bo-Liang Deng
  • OLIGOMER MODIFIED DIAROMATIC SUBSTITUTED COMPOUNDS
    Publication number: 20130040961
    Abstract: Disclosed are compounds comprising diaromatic substituted compound residues, namely the anti-viral (anti-HIV) drug delavirdine, covalently attached via a linkage to water-soluble, non-peptidic oligomers, specifically to poly(ethylene glycol) PEG) oligomers. A compound of the invention, when administered by any of a number of administration routes, exhibits advantages over non-oligomer modified diaromatic substituted compounds.
    Type: Application
    Filed: February 22, 2011
    Publication date: February 14, 2013
    Applicant: Nektar Therapeutics
    Inventors: Jennifer Riggs-Sauthier, Bo-Liang Deng
  • OLIGOMER-OPIOID AGONIST CONJUGATES
    Publication number: 20120289548
    Abstract: The invention provides compounds that are chemically modified by covalent attachment of a water-soluble oligomer. A compound of the invention, when administered by any of a number of administration routes, exhibits characteristics that are different from those of the compound not attached to the water-soluble oligomer.
    Type: Application
    Filed: June 29, 2012
    Publication date: November 15, 2012
    Applicant: Nektar Therapeutics
    Inventors: Jennifer RIGGS-SAUTHIER, Bo-Liang Deng, Timothy A. Riley
  • Oligomer-Opioid Agonist Conjugates
    Publication number: 20120264775
    Abstract: The invention provides compounds that are chemically modified by covalent attachment of a water-soluble oligomer. A compound of the invention, when administered by any of a number of administration routes, exhibits characteristics that are different from those of the compound not attached to the water-soluble oligomer.
    Type: Application
    Filed: March 21, 2012
    Publication date: October 18, 2012
    Applicant: Nektar Therapeutics
    Inventors: Jennifer Riggs-Sauthier, Bo-Liang Deng, Timoty A. Riley
  • Oligomer-Opioid Agonist Conjugates
    Publication number: 20120184581
    Abstract: The invention provides compounds that are chemically modified by covalent attachment of a water-soluble oligomer. A compound of the invention, when administered by any of a number of administration routes, exhibits characteristics that are different from those of the compound not attached to the water-soluble oligomer.
    Type: Application
    Filed: July 21, 2010
    Publication date: July 19, 2012
    Applicant: Nektar Therapeutics
    Inventors: Jennifer Riggs-Sauthier, Bo-Liang Deng, Timothy A. Riley
  • Oligomer-Containing Substituted Aromatic Triazine Compounds
    Publication number: 20120122871
    Abstract: The invention relates to (among other things) oligomer-containing substituted aromatic triazine compounds. A compound of the invention, when administered by any of a number of administration routes, exhibits one or more advantages over corresponding compounds lacking the oligomer.
    Type: Application
    Filed: May 13, 2010
    Publication date: May 17, 2012
    Applicant: Nektar Therapeutics
    Inventors: Jennifer Riggs-Sauthier, Bo-Liang Deng
  • Oligomer-opioid agonist conjugates
    Patent number: 8173666
    Abstract: The invention provides compounds that are chemically modified by covalent attachment of a water-soluble oligomer. A compound of the invention, when administered by any of a number of administration routes, exhibits characteristics that are different from those of the compound not attached to the water-soluble oligomer.
    Type: Grant
    Filed: September 11, 2009
    Date of Patent: May 8, 2012
    Assignee: Nektar Therapeutics
    Inventors: Jennifer Riggs-Sauthier, Bo-Liang Deng, Timothy A. Riley
  • Oligomer-Bis-Chromonyl Compound Conjugates
    Publication number: 20110112183
    Abstract: The invention provides oligomer-bis-chromonyl compound conjugates. The conjugates of the invention, when administered by any of a number of administration routes, exhibits advantages over previously administered compounds.
    Type: Application
    Filed: April 23, 2009
    Publication date: May 12, 2011
    Inventors: Jennifer Riggs-Sauthier, Bo-Liang Deng
  • Oligomer-Calcium Channel Blocker Conjugates
    Publication number: 20110098273
    Abstract: The invention provides small molecule drugs that are chemically modified by covalent attachment of a water soluble oligomer. A conjugate of the invention, when administered by any of a number of administration routes, exhibits characteristics that are different from the characteristics of the small molecule drug not attached to the water soluble oligomer.
    Type: Application
    Filed: September 3, 2008
    Publication date: April 28, 2011
    Applicant: Nektar Therapeutics
    Inventors: Zhongxu Ren, Bo-Liang Deng, Jennifer Riggs-Sauthier, Micah Harvey
  • Oligomer Conjugates of Heteropentacyclic Nucleosides
    Publication number: 20110039797
    Abstract: The invention provides small molecule drugs that are chemically modified by covalent attachment of a water-soluble oligomer.
    Type: Application
    Filed: February 20, 2009
    Publication date: February 17, 2011
    Applicant: Nektar Therapetics
    Inventors: Bo-Liang Deng, Timothy A. Riley, Jennifer Riggs-Sauthier
  • Oligomer Conjugates of Lidocaine and Its Derivatives
    Publication number: 20100303753
    Abstract: The invention provides small molecule drugs that are chemically modified by covalent attachment of a water-soluble oligomer.
    Type: Application
    Filed: October 17, 2008
    Publication date: December 2, 2010
    Applicant: Nektar Therapeutics
    Inventors: Jennifer Riggs-Sauthier, Bo-Liang Deng
  • De Novo Synthesis of Conjugates
    Publication number: 20100184989
    Abstract: The invention provides methods for the preparation of small molecule drugs that are chemically modified by covalent attachment of a water-soluble oligomer obtained from a water-soluble oligomer composition. Such drugs are produced through modification of a synthetic pathway to attach the oligomer to an intermediate compound followed by completion of the synthetic path.
    Type: Application
    Filed: March 12, 2008
    Publication date: July 22, 2010
    Applicant: Nektar Therapeutics
    Inventors: Jennifer Riggs-Sauthier, Bo-Liang Deng, Zhongxu Ren, Wen Zhang, Xuyuan Gu, Franco J. Duarte
  • Oligomer-Anticholinergic Agent Conjugates
    Publication number: 20100168232
    Abstract: The invention provides anticholinergic agents that are chemically modified by covalent attachment of a water-soluble oligomer. A conjugate of the invention, when administered by any of a number of administration routes, exhibits characteristics that are different as compared to the characteristics of the anticholinergic agent not attached to the water-soluble oligomer.
    Type: Application
    Filed: March 12, 2008
    Publication date: July 1, 2010
    Applicant: Nektar Therapeutics
    Inventors: Jennifer Riggs-Sauthier, Bo-Liang Deng
  • Oligomer-Opioid Agonist Conjugates
    Publication number: 20100048602
    Abstract: The invention provides compounds that are chemically modified by covalent attachment of a water-soluble oligomer. A compound of the invention, when administered by any of a number of administration routes, exhibits characteristics that are different from those of the compound not attached to the water-soluble oligomer.
    Type: Application
    Filed: September 11, 2009
    Publication date: February 25, 2010
    Applicant: Nektar Therapeutics
    Inventors: Jennifer Riggs-Sauthier, Bo-Liang Deng, Timothy A. Riley
  • Alkenyldiarylmethanes, Fused Analogs And Syntheses Thereof
    Publication number: 20080300288
    Abstract: Non-nucleoside inhibitors of HIV-1 reverse transcriptase are described. Such inhibitors may be used as part of a combination therapy to treat HIV infection. Compounds described herein exhibit antiviral potency. In addition, compounds described herein exhibit metabolic stability. Also described herein are processes for preparing Non-nucleoside inhibitors of HIV-1 reverse transcriptase.
    Type: Application
    Filed: June 29, 2006
    Publication date: December 4, 2008
    Applicant: PURDUE RESEARCH FOUNDATION
    Inventors: Mark S. Cushman, Bo-Liang Deng