Abstract: A medical device includes a sheath; a balloon disposed over at least a portion of the sheath; and a flexible framework including an expandable region and a non-expandable region. The expandable region is formed on an inflatable portion of the balloon and includes longitudinal extending arms, each arm including one or more layers of dielectric material, one or more conductive traces, and one or more electrodes electrically connected to the one or more conductive traces. The non-expandable region is formed on a non-inflatable portion of the balloon or the sheath and includes one or more layers of dielectric material, the one or more conductive traces, and one or more contacts electrically connected to the one or more conductive traces. A cable including a plurality of wires that are electrically connected to the one or more contacts.

Abstract: Embodiments relate to an implantable device. Specifically, a device includes a flexible connection component that includes a set of conductive filaments that connect a set of electrodes (or traces connected to the electrodes) and circuitry that receives and/or transmits electronic signals from and/or to the electrodes.

Abstract: The present disclosure is related to a method of producing a capsule. The method includes providing a mold, depositing parylene on the mold to form a parylene layer, scoring the parylene layer, and coating the parylene layer with a polymer to produce a capsule.

Abstract: The present disclosure provides methods and apparatuses for implementing video effect addition. At a target application, an original video frame may be obtained from a video source; the original video frame may be provided to a video effect processing application, the video effect processing application being a Web application; and a processed video frame to which a video effect is applied may be obtained from the video effect processing application. At a video effect processing application, an original video frame may be obtained from a target application; a video effect may be applied to the original video frame to obtain a processed video frame; and the processed video frame may be provided to the target application.

Abstract: A display method, an apparatus, and a storage medium are provided. The method includes: rendering, by a first container, a to-be-displayed page to generate to-be-displayed image data, and encrypting the image data; and writing, by the first container, encrypted image data into a buffer corresponding to the first container, and sending instruction information to a second container of a terminal, where the instruction information is used to instruct the second container to securely display the encrypted image data. Because the containers are isolated from each other, the malware in the first container cannot access the image data displayed in the second container, and the second container securely displays the encrypted image data. In this way, security of displaying the image data can be improved while ensuring that an image display function is not restricted.

Abstract: The present disclosure relates to mapping catheters, and in particular to mapping catheters having thin film electrodes used in sensing electrical activity within a patient. Particularly, aspects of the present disclosure are directed to a medical device having a hollow core, a balloon disposed over at least a portion of the hollow core, and a flexible framework having one or more thin film elements formed on at least a portion of the balloon. The one or more thin film elements comprise a plurality of mapping electrodes.

Abstract: A method is used to generate a distortion model for a structured illumination microscopy (SIM) optical system. A sliding window is moved in relation to a plurality of images to define a plurality of sub-tiles. Each sub-tile represents a portion of the corresponding image. Parameters are estimated for each sub-tiles. The parameters include two or more parameters selected from the group consisting of modulation, angle, spacing, phase offset, and phase deviation. A full width at half maximum (FWHM) value associated with each sub-tile is estimated. A distortion model is estimated, based at least in part on a combination of the estimated parameters and FWHM values stored in the predetermined format and an estimated center window parameter. A two-dimensional image may be generated, based at least in part on the estimated distortion model. The two-dimensional image may include representations indicating where distortions occur in the optical system.

Abstract: The present disclosure relates to branched proximal connectors for high density neural interfaces and methods of microfabricating the branched proximal connectors. Particularly, aspects of the present disclosure are directed to a branched connector that includes a main body having a base portion of a supporting structure and a plurality of conductive traces formed on the base portion, and a plurality of plugs extending from the main body. Each plug of the plurality of plugs include an end portion of the supporting structure comprised of the one or more layers of dielectric material, and a subset of conductive traces from the plurality of conductive traces. Each trace from the subset of conductive traces terminates at a bond pad exposed on a surface of the end portion of the supporting structure.

Abstract: The present disclosure relates to connectors for high density neural interfaces and methods of microfabricating the connectors. Particularly, aspects of the present disclosure are directed to a connector having a main body, a first plug extending from the main body, a flexible bridge extending from the main body or the first plug, and a second plug extending from the flexible bridge. This structure allows for the main body, the first plug, and the second plug to be arranged in tandem on a longitudinal axis of the main body, which enables the connector to be passed through a narrow diameter cannula. This structure also allows for the first plug and the second plug to be arranged in a spread out orientation, which enables the connector to be electrically connected with a neurostimulator.

Abstract: Some examples relate to a method for characterizing polynucleotides in a sample. First polynucleotides coupled to a first substrate may be hybridized to second polynucleotides in a sample. First labeled nucleotides may be added to the first polynucleotides using a sequence of the second polynucleotides. A first signal intensity from the first labeled nucleotides is measured. Second labeled nucleotides are added to the first polynucleotides using the sequence of the second polynucleotides. A second signal intensity from the second labeled nucleotides is measured. The first signal intensity is normalized using the second signal intensity. The normalized first signal intensity characterizes the second polynucleotides in the sample.

Abstract: According to one aspect of the present disclosure, a method of wireless communication of a first node is provided. The method may include generating, by at least one processor, a first low-power listening (LPL) frame with a first LPL subfield set to “enable.” The method may include transmitting, by a communication interface, the first LPL frame with the first LPL subfield set to “enable” to a second node. The method may include enabling, by the at least one processor, an LPL mode after the first LPL frame with the first LPL subfield set to “enable” is transmitted to the second node.

Abstract: A lightning protective and heating porcelain tile includes a porcelain tile layer, a shell, a metal plate protective layer, and an electric heating film heating layer. The metal plate protective layer is attached to the inner wall of the porcelain tile layer, and the electric heating film heating layer is attached to the metal plate protective layer. The electric heating film heating layer includes an electric heating film, a first lightning protective module and a second lightning protective module. The hot wire and neutral wire connected to the electric heating film are electrically connected to the first lightning protective module and the second lightning protective module, respectively. The first lightning protective module and the second lightning protective module are electrically connected to the metal plate protective layer individually. The first lightning protective module and the second lightning protective module are made of varistors.

Abstract: The technology disclosed extracts intensities from sequencing images for base calling target clusters and attenuates spatial crosstalk from neighboring clusters. The technology disclosed accesses a particular section from a plurality of sections of an image output by a sensor, the particular section of the image including at least one pixel depicting intensity emission values from a target cluster and neighboring clusters located across the sensor, and convolves the particular section of the image with a corresponding convolution kernel in a plurality of convolution kernels, to generate a feature map comprising a plurality of feature values. The technology disclosed further assigns a corresponding feature value to the target cluster based on feature values in the plurality of feature values adjoining a center of the target cluster, and processes the corresponding feature value assigned to the target cluster, to base call the target cluster.

Abstract: The present disclosure relates to connectors for high density neural interfaces and methods of microfabricating the connectors. Particularly, aspects of the present disclosure are directed to a connector having a core and a supporting structure wrapped around at least a portion of the core. The supporting structure may have a first layer of a high temperature liquid crystal polymer, and the second layer of a low temperature liquid crystal polymer that is reflowed to attach the supporting structure to the core. Conductive traces are buried between the first layer and the second layer, and the conductive traces terminate at conductive contacts formed on a surface of the first layer. The connector may have a predetermined shape or profile, which facilitates alignment and insertion of the connector into a header of a neurostimulator.

Abstract: The present disclosure relates to a monolithic thin-film lead assembly and methods of microfabricating a monolithic thin-film lead assembly. Particularly, aspects of the present disclosure are directed to a monolithic thin-film lead assembly that includes a cable having a proximal end, a distal end, a supporting structure that extends from the proximal end to the distal end, and a plurality of conductive traces formed on a portion of the supporting structure. The supporting structure includes one or more layers of dielectric material. The monolithic thin-film lead assembly may further include an electrode assembly formed on the supporting structure at the distal end of the cable. The electrode assembly includes one or more electrodes in electrical connection with one or more conductive traces of the plurality of conductive traces.

Abstract: A stimulation system can include one or more stimulating components, each of which can include one or more electrodes and one or more leads. Each lead can be connected at a first end of the lead to an electrode of the one or more electrodes and can be connected at a second end of the lead to a bonding pad of the one or more bonding pads. The stimulation system can also include a cylindrical substrate. Each stimulating component can be secured to a surface of the cylindrical substrate. The stimulation system can further include a skull-mount package that includes electronics that identify stimulation parameters. The bonding pads can be electrically connected to the electronics. The skull-mount package can further include one or more bonding pads. Each lead can be directly electrically and physically connected to a bonding pad of the one or more bonding pads.

Abstract: Biological sample testing devices, and associated systems and methods, are disclosed herein. In some embodiments, the biological sample testing device includes a slide, a spacer layer carried by the slide, and a cover slip carried by the slide over the spacer layer. The spacer layer includes one or more wells, each of which extend horizontally along a first axis from an inlet at a first side of the biological sample testing device to an outlet at a second side of the biological sample testing device opposite the first side. Each well is defined by a set of curved sidewalls that extend from the inlet to the outlet. Further, the set of curved sidewalls define an asymmetric shape for the well about a second axis perpendicular to the first axis. The shape manages a flow of a biological sample to reduce a chance of bubbling within the well.

Abstract: The present disclosure relates to connectors for high density neural interfaces and methods of microfabricating the connectors. Particularly, aspects of the present disclosure are directed to a connector having a core and a supporting structure wrapped around at least a portion of the core. The supporting structure may have a first layer of a high temperature liquid crystal polymer, and the second layer of a low temperature liquid crystal polymer that is reflowed to attach the supporting structure to the core. Conductive traces are buried between the first layer and the second layer, and the conductive traces terminate at conductive contacts formed on a surface of the first layer. The connector may have a predetermined shape or profile, which facilitates alignment and insertion of the connector into a header of a neurostimulator.

Abstract: The present disclosure relates to a medical device, methods of making a medical device, and methods of delivering medical device. Particularly, aspects of the present disclosure are directed to a medical device having a self-expanding stent and a thin-film neural interface. The stent comprises a plurality of struts having a substantially elliptical or circular geometry arranged in series from a proximal end to a distal end of the stent, and a thin-film neural interface attached to the stent. Each strut of the self-expanding stent comprises a top portion and a base portion integrally connected with the top portion at a first connection point and a second connection point such that the top portion moves relative to the base portion. The self-expanding stent provides a retracted configuration to protect the thin-film neural interface during delivery, and an expanded configuration to deploy the thin-film neural interface.

Abstract: The technology disclosed extracts intensities from sequencing images for base calling target clusters and attenuates spatial crosstalk from neighboring clusters. The technology disclosed accesses a particular section from a plurality of sections of an image output by a sensor, the particular section of the image including at least one pixel depicting intensity emission values from a target cluster and neighboring clusters located across the sensor, and convolves the particular section of the image with a corresponding convolution kernel in a plurality of convolution kernels, to generate a feature map comprising a plurality of feature values. The technology disclosed further assigns a corresponding feature value to the target cluster based on feature values in the plurality of feature values adjoining a center of the target cluster, and processes the corresponding feature value assigned to the target cluster, to base call the target cluster.