Abstract: The present disclosure provides an equivalent aggregation method and an apparatus for an electro-thermal coupled virtual power plant. The method includes: obtaining an equivalence model in a heating section of the electro-thermal coupled virtual power plant by training a support vector machine; establishing a computing model for equivalent aggregation of the electro-thermal coupled virtual power plant; and realizing the equivalent aggregation of the electro-thermal coupled virtual power plant by solving the computing model for the equivalent aggregation of the electro-thermal coupled virtual power plant.

Abstract: An endoscopic device, including an illumination channel; an imaging channel parallel to the illumination channel and having a different longitudinal axis from a longitudinal axis of the illumination channel; a laser diode at a proximal end of the illumination channel and offset from the longitudinal axis of the illumination channel and configured to emit a laser; at least one imaging sensor at a proximal end of the imaging channel and offset from the longitudinal axis of the imaging channel; a laser pathway shifter between the laser diode and the proximal end of the illumination channel and configured to change a propagation direction of the laser; and an imaging pathway shifter between the proximal end of the imaging channel and the at least one imaging sensor and configured to change a propagation direction of light from the imaging channel.

Abstract: A non-invasive imaging system and method for visualizing cranial sutures through overlying tissue are disclosed. The system includes a near-infrared and/or short-wave infrared illumination source, an imaging device that detects reflected short-wave infrared radiation, a linear polarizer, and a long-pass filter arranged in an optical path between a cranial region and the imaging device. The linear polarizer reduces surface-reflected light, and the long-pass filter attenuates wavelengths below a selected cutoff wavelength while passing short-wave infrared light reflected from beneath overlying tissue. Detected short-wave infrared radiation is provided to processing circuitry that generates image data representing cranial suture morphology. The disclosed approach enables evaluation of cranial sutures in the absence of ionizing radiation.

Abstract: The present disclosure relates to non-invasive nerve identification using snapshot polarimetry. The present disclosure further relates to a system for nerve identification, the system comprising a camera including a sensor, and a filter having a linear polarizer array, an illumination system configured to illuminate a target area with polarized light illumination, the polarized light illumination having at least one predetermined polarization angle, the illumination system including one more light sources, and one or more polarizer filters, and a processor configured to process imaging data obtained from the camera, and output a birefringence map of the target area including indicia of a nerve structure.

Abstract: In certain embodiments, this disclosure provides methods to generate DNA, RNA and/or DNA-peptide nanostructures based chimeric antigen receptor (CAR) T cell (engineered T cell) for cancer immunotherapy, and compositions made by these methods.

Abstract: In certain embodiments, this disclosure provides methods to generate DNA, RNA and/or DNA-peptide nanostructures based chimeric antigen receptor (CAR) T cell (engineered T cell) for cancer immunotherapy, and compositions made by these methods.

Abstract: The present disclosure provides an equivalent aggregation method and an apparatus for an electro-thermal coupled virtual power plant. The method includes: obtaining an equivalence model in a heating section of the electro-thermal coupled virtual power plant by training a support vector machine; establishing a computing model for equivalent aggregation of the electro-thermal coupled virtual power plant; and realizing the equivalent aggregation of the electro-thermal coupled virtual power plant by solving the computing model for the equivalent aggregation of the electro-thermal coupled virtual power plant.

Abstract: Method and system for detecting disease in blood sample is described. By extracting extracellular vesicles (EVs) from the blood sample and employing liposome fusion probes, it is shown that the test can be completed within hours instead of weeks, and the detection limit can be significantly lowered.

Abstract: The present disclosure describes a method for detecting the presence of Mycobacterium tuberculosis in a bodily fluid sample. The method utilizes CRISPR effector proteins along with a guide RNA and a reporter molecule, such that when the guide RNA hybridizes with a target nucleotide fragment, the CRISPR effector protein cleaves the reporter molecule, resulting in a detectable signal.

Abstract: Disclosed are a virtual power plant operation risk analysis method and a device. The method comprises: establishing a multi-state model of wind turbine output, analyzing influence of wind speed on wind turbine failure rate based on the multi-state model of wind turbine output, and establishing a wind turbine failure model considering wind turbine time-varying failure rate; establishing a multi-state model of wind turbine output considering the wind speed and the wind turbine time-varying failure rate by an improved general generating function method based on the multi-state model of wind turbine output and the wind turbine failure model considering the wind turbine time-varying failure rate; establishing a multi-state output model of virtual power plant based on the multi-state model of wind turbine output considering wind speed and wind turbine time-varying failure rate; and calculating operation risk indicators of virtual power plant through the multi-state output model of virtual power plant.

Abstract: This disclosure describes a method and system for active machine learning model that automatically and continuously improve the model with high accuracy, sensitivity, specificity and universality.

Abstract: The present disclosure relates to genetically modified strains of Salmonella, engineered to be tumor navigating and to alter tumor metabolism in the tumor microenvironment. Also provided herein are methods of producing and methods of using such genetically modified Salmonella strains to treat cancer.

Abstract: The present disclosure describes a method for detecting the presence of pathogens, including SARS-CoV-2, in a sample. The method utilizes CRISPR effector proteins along with a guide RNA and a reporter molecule. RNAs in the sample are first optionally extracted and reverse transcribed, followed by amplification, such that when the guide RNA hybridizes with a target nucleotide fragment in the amplified DNA, the CRISPR effector protein cleaves the reporter molecule, resulting in a detectable signal.

Abstract: The present disclosure describes a method for detecting the presence of Mycobacterium tuberculosis in a bodily fluid sample. The method utilizes CRISPR effector proteins along with a guide RNA and a reporter molecule, such that when the guide RNA hybridizes with a target nucleotide fragment, the CRISPR effector protein cleaves the reporter molecule, resulting in a detectable signal.

Abstract: The present disclosure relates to non-invasive nerve identification using snapshot polarimetry. The present disclosure further relates to a system for nerve identification, the system comprising a camera including a sensor, and a filter having a linear polarizer array, an illumination system configured to illuminate a target area with polarized light illumination, the polarized light illumination having at least one predetermined polarization angle, the illumination system including one more light sources, and one or more polarizer filters, and a processor configured to process imaging data obtained from the camera, and output a birefringence map of the target area including indicia of a nerve structure.

Abstract: Provided are a connection structure and system of an integrated brake device for a rail vehicle. The connection structure of an integrated brake device for a rail vehicle includes a brake valve, a dust collector, an intermediate body, an air cylinder, a support assembly and a connection assembly. The intermediate body is of a plate-type structure, the brake valve and the dust collector are mounted on one side of the intermediate body, the air cylinder is connected to the intermediate body by means of the connection assembly, the air cylinder is mounted on the other side of the intermediate body, and the support assembly is located between the air cylinder and the intermediate body. The connection structure of an integrated brake device for a rail vehicle has a simple and compact structure and saves on space.

Abstract: The present disclosure relates to genetically modified strains of Salmonella, engineered to be tumor navigating and to alter tumor metabolism in the tumor microenvironment. Also provided herein are methods of producing and methods of using such genetically modified Salmonella strains to treat cancer.

Abstract: In certain embodiments, this disclosure provides methods to generate DNA. RNA and/or DNA-peptide nanostructures based chimeric antigen receptor (CAR) T cell (engineered T cell) for cancer immunotherapy, and compositions made by these methods.

Abstract: Provided are a connection structure and system of an integrated brake device for a rail vehicle. The connection structure of an integrated brake device for a rail vehicle includes a brake valve, a dust collector, an intermediate body, an air cylinder, a support assembly and a connection assembly. The intermediate body is of a plate-type structure, the brake valve and the dust collector are mounted on one side of the intermediate body, the air cylinder is connected to the intermediate body by means of the connection assembly, the air cylinder is mounted on the other side of the intermediate body, and the support assembly is located between the air cylinder and the intermediate body. The connection structure of an integrated brake device for a rail vehicle has a simple and compact structure and saves on space.

Abstract: The present application discloses an automatic powder cleaning process and device for wheel bolt holes. The device comprises a vacuum pump, a steady pressure tank, a powder cleaning robot, a powder cleaning gun, a control system and accessories. According to the process and the device, shielded protection is canceled, and powder at the mounting part of a wheel bolt hole is automatically cleaned, so that the process and the device are suitable for various wheel products, and the labor and the labor cost are reduced; the problems that a lot of different types of protective plugs needed for wheels are inconvenient to customize and store and high in cost are avoided.