Patents by Inventor Bo Qiu

Bo Qiu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20030040126
    Abstract: Immunologically invisible carrier molecules connect a plurality of copies of an immunologically active molecule in an immunologic assay.
    Type: Application
    Filed: October 17, 2001
    Publication date: February 27, 2003
    Inventors: Bo Qiu, Guobao Zhang, Stanley Stein, Leonard H. Sigal, Michael Brunner, Michael Katz
  • Publication number: 20030040127
    Abstract: Immunologically invisible carrier molecules connect a plurality of copies of an immunologically active molecule in an immunologic assay
    Type: Application
    Filed: October 17, 2001
    Publication date: February 27, 2003
    Inventors: Bo Qiu, Stanley Stein, Guobao Zhang, Leonard Sigal, Michael Brunner, Michael Katz
  • Publication number: 20030031674
    Abstract: Immunologically invisible carrier molecules connect a plurality of copies of an immunologically active molecule in an immunologic assay.
    Type: Application
    Filed: October 17, 2001
    Publication date: February 13, 2003
    Inventors: Bo Qiu, Guobao Zhang, Stanley Stein, Leonard Sigal, Michael Brunner, Michael Katz
  • Publication number: 20020197271
    Abstract: Immunologically invisible carrier molecules connect a plurality of copies of an immunologically active molecule in an immunologic assay.
    Type: Application
    Filed: October 17, 2001
    Publication date: December 26, 2002
    Inventors: Bo Qiu, Guobao Zhang, Stanely Stein, Leonard Sigal, Michael Brunner, Michael Katz
  • Patent number: 6468522
    Abstract: This invention pertains to disulfide-linked conjugates of therapeutic agents containing at least one thioamide group with polymer comprising at least one thiol group, so as to provide a controlled release pharmaceutical composition for administration to animals for the prophylaxis or treatment of various conditions or diseases. The therapeutic agent conjugate may comprise an inactive or weakly active prodrug form which may be converted into the original therapeutic compound by the natural action of reducing agents in vivo. The composition may comprise a mixture of polymers each with a different thioamide-containing agent attached, or a polymer conjugated with a mixture of thioamide-containing agents.
    Type: Grant
    Filed: July 21, 2000
    Date of Patent: October 22, 2002
    Assignees: University of Medicine and Dentistry of New Jersey, Rutgers, the State University of New Jersey
    Inventors: Stanley Stein, Guobao Zhang, Bo Qiu
  • Publication number: 20020122785
    Abstract: This invention pertains to disulfide-linked conjugates of therapeutic agents containing at least one thioamide group with polymer comprising at least one thiol group, so as to provide a controlled release pharmaceutical composition for administration to animals for the prophylaxis or treatment of various conditions or diseases. The therapeutic agent conjugate may comprise an inactive or weakly active prodrug form which may be converted into the original therapeutic compound by the natural action of reducing agents in vivo. The composition may comprise a mixture of polymers each with a different thioamide-containing agent attached, or a polymer conjugated with a mixture of thioamide-containing agents.
    Type: Application
    Filed: May 1, 2002
    Publication date: September 5, 2002
    Inventors: Stanley Stein, Guobao Zhang, Bo Qiu
  • Publication number: 20020106706
    Abstract: Immunologically invisible carrier molecules connect a plurality of copies of an immunologically active molecule in an immunologic assay.
    Type: Application
    Filed: October 17, 2001
    Publication date: August 8, 2002
    Inventors: Bo Qiu, Stanley Stein, Guobao Zhang, Leonard Sigal, Michael Brunner, Michael Katz
  • Publication number: 20020076443
    Abstract: The present invention is directed to pharmaceutical compositions, and method for preparing pharmaceutical compositions, comprising a cross-linked matrix physically entrapping at least one therapeutic agent. The matrix may comprise one or more phases in addition to an aqueous phase, such as a solid and/or oil phase. The matrix of the invention has at least one controlled release in-vivo kinetic profile, and may have additional profiles for the same agent. The matrix may also comprise more than one therapeutic agent, and each additional therapeutic agent may have one or more controlled release in-vivo kinetic profile.
    Type: Application
    Filed: June 18, 2001
    Publication date: June 20, 2002
    Inventors: Stanley Stein, Bo Qiu