Patents by Inventor Bo R. Lamm

Bo R. Lamm has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Separation of enantiomers of non-steroidal anti-inflammatory drugs and chiral selector therefor
    Patent number: 5484530
    Abstract: The invention relates to a chiral selector useful in separating underivatized enantiomers of nonsterodial anti-inflammatory agents, particularly naproxen and other arylacetic acid compounds, and relates to a process for achieving such separation utilizing the chiral selector, which is also useful in achieving the enantiomeric separation of amines, alcohol derivatives, epoxides and sulfoxides. The invention is also directed to an apparatus which comprises the chiral selectors.
    Type: Grant
    Filed: October 11, 1994
    Date of Patent: January 16, 1996
    Assignee: Research Corporation Technologies, Inc.
    Inventors: William H. Pirkle, Christopher J. Welch, Bo R. Lamm
  • Separation of enantiomers of non-steroidal anti-inflammatory drugs and chiral selector therefor
    Patent number: 5387338
    Abstract: The invention relates to a chiral selector useful in separating underivatized enantiomers of nonsterodial anti-inflammatory agents, particularly naproxen and other arylacetic acid compounds, and relates to a process for achieving such separation utilizing the chiral selector, which is also useful in achieving the enantiomeric separation of amines, alcohol derivatives, epoxides and sulfoxides. The invention is also directed to an apparatus which comprises the chiral selectors.
    Type: Grant
    Filed: July 9, 1993
    Date of Patent: February 7, 1995
    Assignee: Research Corporation Technologies, Inc.
    Inventors: William H. Pirkle, Christopher J. Welch, Bo R. Lamm
  • Separation of enantiomers of non-steroidal anti-inflammatory drugs and chiral selector therefor
    Patent number: 5256293
    Abstract: The invention relates to a chiral selector useful in separating underivatized enantiomers of nonsterodial anti-inflammatory agents, particularly naproxen and other arylacetic acid compounds, and relates to a process for achieving such separation utilizing the chiral selector, which is also useful in achieving the enantiomeric separation of amines, alcohol derivatives, epoxides and sulfoxides. The invention is also directed to an apparatus which comprises the chiral selectors.
    Type: Grant
    Filed: March 9, 1992
    Date of Patent: October 26, 1993
    Assignee: Research Corporation Technologies, Inc.
    Inventors: William H. Pirkle, Christopher J. Welch, Bo R. Lamm
  • Stereoisomers of benzonitrile derivatives, useful as cardiac arrhythmiac agents
    Patent number: 5055490
    Abstract: 4-[3-[ethyl[3-((R*)-propylsulfinyl)propyl]amino]-2(R)-hydroxypropoxy]-benzo nitrile,4-[3-[ethyl[3-((S*)-propylsulfinyl)propyl]amino]-2(R)-hydroxypropoxy]-benzo nitrile,4-[3-[ethyl[3-((R*)-propylsulfinyl)propyl]amino]-2(S)-hydroxypropoxy]-benzo nitrile,4-[3-[ethyl[3-[((S*)-propylsulfinyl)propyl]amino]-2(S)-hydroxypropoxy]-benz onitrile andpharmaceutically acceptable salt thereof, processes for their preparation, as well as the use of said compounds for the preparation of medicaments with action against cardiac arrhythmias.
    Type: Grant
    Filed: June 18, 1990
    Date of Patent: October 8, 1991
    Assignee: Aktiebolaget Hassle
    Inventors: Olle K. S. Almgren, Kjell H. Andersson, Goran B. D. Duker, Bo R. Lamm, Gert C. Strandlund
  • Method for the synthesis of pharmacologically active compounds and intermediates for such synthesis
    Patent number: 4777293
    Abstract: A process for the preparation of an aryloxypropanolamine of the formulaAr--OCH.sub.2 CH(OH)CH.sub.2 NH--R Iwherein Ar is a carbocyclic or heterocyclic aromatic group and R is an alkyl or substituted alkyl group having 1 to 6 carbon atoms, characterized in subjecting a compound of the formula ##STR1## to oxidative cleavage to a dialdehyde of the formula ##STR2## which is then made subject to reduction, amination, acetal hydrolysis, and, where required, removal of a nitrogen protective group, to the formation of a compound of formula I, or an acid addition salt thereof, a compound of formula II and the preparation thereof from mannitol.
    Type: Grant
    Filed: July 10, 1985
    Date of Patent: October 11, 1988
    Assignee: Aktiebolaget Hassle
    Inventor: Bo R. Lamm
  • Processes for the preparation of omeprazole and intermediates therefore
    Patent number: 4620008
    Abstract: Novel compounds of the formula ##STR1## wherein R is H or CH.sub.3, a process for their preparation, and their use as intermediates in the preparation of pharmaceutically useful compounds, e.g. substituted benzimidazoles containing a pyridine radical, i.a. omeprazole.
    Type: Grant
    Filed: February 1, 1985
    Date of Patent: October 28, 1986
    Assignee: Aktiebolaget Hassle
    Inventors: Arne E. Brandstrom, Bo R. Lamm
  • Certain pyridyl-N-oxide intermediates for the preparation of omeprazole
    Patent number: 4544750
    Abstract: Novel compounds of the formula ##STR1## wherein R is H or CH.sub.3, a process for their preparation, and their use as intermediates in the preparation of pharmaceutically useful compounds, e.g. substituted benzimidazoles containing a pyridine radical, i.a. omeprazole.
    Type: Grant
    Filed: August 26, 1983
    Date of Patent: October 1, 1985
    Assignee: Aktiebolaget Hassle
    Inventors: Arne E. Brandstrom, Bo R. Lamm