Patents by Inventor Bo Shui

Bo Shui has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Functional nucleic acid ligands to fluorescent proteins
    Patent number: 8445655
    Abstract: The present invention relates to a nucleic acid aptamer having a first domain that binds to a fluorescent protein. The nucleic acid aptamer forms a molecular complex whereby the aptamer binds a fluorescent protein at the first domain. A constructed DNA molecule, expression systems, and host cells containing the molecular complex are also disclosed. The invention also relates to a system containing a first DNA molecule encoding the nucleic acid aptamer of the present invention and a second DNA molecule encoding a fluorescent protein capable of being bound by the first domain. Methods of detecting a molecular target and determining location of a molecular target using the nucleic acid aptamer of the invention are also disclosed.
    Type: Grant
    Filed: June 18, 2007
    Date of Patent: May 21, 2013
    Assignee: Cornell Research Foundation, Inc.
    Inventors: Michael Kotlikoff, John T. Lis, Bo Shui, Hua Shi
  • FUNCTIONAL NUCLEIC ACID LIGANDS TO FLUORESCENT PROTEINS
    Publication number: 20090197271
    Abstract: The present invention relates to a nucleic acid aptamer having a first domain that binds to a fluorescent protein. The nucleic acid aptamer forms a molecular complex whereby the aptamer binds a fluorescent protein at the first domain. A constructed DNA molecule, expression systems, and host cells containing the molecular complex are also disclosed. The invention also relates to a system containing a first DNA molecule encoding the nucleic acid aptamer of the present invention and a second DNA molecule encoding a fluorescent protein capable of being bound by the first domain. Methods of detecting a molecular target and determining location of a molecular target using the nucleic acid aptamer of the invention are also disclosed.
    Type: Application
    Filed: June 18, 2007
    Publication date: August 6, 2009
    Applicant: CORNELL RESEARCH FOUNDATION, INC.
    Inventors: Michael Kotlikoff, Hua Shi, Bo Shui, John T. Lis