Patents by Inventor Bo Skaaning Jensen

Bo Skaaning Jensen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Ion channel modulating agents
    Patent number: 7012146
    Abstract: The present invention relates to ion channel modulating agents. More particularly, the present invention relates to a particular class of chemical compounds that has proven useful as modulators of SK Ca, IK Ca and BK Ca channels. In further aspects, the present invention relates to the use of these SK/IK/BK channel modulating agents for the manufacture of medicaments, for methods of therapy, and pharmaceutical compositions comprising the SK/IK/BK channel modulating agents. The SK/IK/BK channel modulating agents of the invention are useful for the treatment or alleviation of diseases and conditions associated with the SK/IK/BK channels.
    Type: Grant
    Filed: May 15, 2001
    Date of Patent: March 14, 2006
    Assignee: Poseidon Pharmaceuticals A/S
    Inventors: Bo Skaaning Jensen, Dorte Strobaek, Palle Christophersen, Lene Teuber, Jurgen Beyer
  • Use of isatin derivatives as ion channel activating agents
    Patent number: 6969729
    Abstract: The present invention relates to ion channel activating agents. More particularly, the present invention relates to a particular class of chemical compounds that has proven useful as openers of SKCa and IKCa channels. In further aspects, the present invention relates to the use of these SK/IK channel activating agents for the manufacture of medicaments and pharmaceutical compositions comprising the SK/IK channel activating agents.
    Type: Grant
    Filed: October 16, 2002
    Date of Patent: November 29, 2005
    Assignee: Neurosearch A/S
    Inventors: Bo Skaaning Jensen, Tino Dyhring Jørgensen, Philip K. Ahring, Palle Christophersen, Dorte Strøbaek, Lene Teuber, Søren Peter Olesen
  • Chemical compounds having ion channel blocking activity for the treatment of immune dysfunction
    Patent number: 6797694
    Abstract: The present invention relates to chemical compounds having inhibitory activity on an intermediate conductance Ca2+ activated potassium channel (IKCa), and the use of such compounds for the treatment or alleviation of diseases or conditions relating to immune dysfunction.
    Type: Grant
    Filed: November 9, 2001
    Date of Patent: September 28, 2004
    Assignee: Poseidon Pharmaceuticals A/S
    Inventors: Bo Skaaning Jensen, Soren Peter Olsen, Palle Christophersen
  • G-protein coupled receptor arrays
    Publication number: 20040171008
    Abstract: The invention relates to G-protein coupled receptor (GPCR) arrays, methods for production of GPCR arrays, primers used in the production of GPCR arrays and kits containing GPCR arrays and further to the use of such GPCR arrays in methods for the determination of expression profiles in biological materials in which there is an interest in the expression of GPCR polynucleotides.
    Type: Application
    Filed: November 12, 2003
    Publication date: September 2, 2004
    Inventors: Kenneth Thirstrup, Lars Siim Madsen, Jens Bitsch Jensen, Rene Hummel, Bo Skaaning Jensen
  • Ion channel modulating agents
    Patent number: 6759422
    Abstract: The present invention relates to ion channel modulating agents. More particularly, the present invention relates to a particular class of chemical compounds represented by general formula (I) that has proven useful as modulators of SKCa, IKCa and BKCa channels. In further aspects, the present invention relates to the use of these SK/IK/BK channel modulating agents for the manufacture of medicaments and pharmaceutical compositions comprising the SK/IK/BK channel modulating agents. The SK/IK/BK channel modulating agents of the invention are useful for the treatment or alleviation of diseases and conditions associated with the SK/IK/BK channels.
    Type: Grant
    Filed: August 2, 2002
    Date of Patent: July 6, 2004
    Assignee: Neurosearch A/S
    Inventors: Bo Skaaning Jensen, Lene Teuber, Dorte Strobaek, Palle Christophersen, Soren Peter Olesen
  • Ion channel arrays
    Publication number: 20040118060
    Abstract: The invention relates to ion channel arrays, method of producing such an array, including the primer sets and kits comprising the ion channel array. The invention also relates to a subset of methods for the evaluation of ion channel expression profiles using the ion channel array such as expression profile of a certain biological material, several biological materials and to identify therapeutic, prophylactic and/or toxic agents involved either directly or indirectly in the response of the ion channel expression.
    Type: Application
    Filed: December 18, 2003
    Publication date: June 24, 2004
    Inventors: Bo Skaaning Jensen, Lars Siim Madsen, Jens Bitsch Jensen, Katrine Kjaer
  • Benzimidazolone-, benzoxazolone-, or benzothiazolone derivatives as ion channel modulating agents
    Publication number: 20040029937
    Abstract: The present invention relates to ion channel modulating agents. More particularly, the present invention relates to a particular class of chemical compounds that has proven useful as modulators of SKCa, IKCa and BKCa channels. In further aspects, the present invention relates to the use of these SK/IK/BK channel modulating agents for the manufacture of medicaments, and pharmaceutical compositions comprising the SK/IK/BK channel modulating agents.
    Type: Application
    Filed: July 1, 2003
    Publication date: February 12, 2004
    Applicant: NEUROSEARCH A/S.
    Inventors: Lene Teuber, Palle Christophersen, Dorte Strobaek, Bo Skaaning Jensen
  • Use of 3-substituted oxindole derivatives as kcnq potassium channel modulators
    Publication number: 20030181507
    Abstract: The present invention relates to a novel method of treating of pain or anxiety, using compounds that modulate KCNQ potassium channels and currents.
    Type: Application
    Filed: February 24, 2003
    Publication date: September 25, 2003
    Inventors: Bo Skaaning Jensen, Rikke Schroder, Dorte Strobaek, Soren Peter Olesen
  • Ion channel modulating agents comprising novel benzimidazolone derivatives
    Patent number: 6624186
    Abstract: The present invention relates to ion channel modulating agents. More particularly, the present invention relates to a particular class of chemical compounds that has proven useful as modulators of SKCa, IKCa and BKCa channels. In further aspects, the present invention relates to the use of these SK/IK/BK channel modulating agents for the manufacture of medicaments, and pharmaceutical compositions comprising the SK/IK/BK channel modulating agents. The SK/IK/BK channel modulating agents of the invention are useful for the treatment or alleviation of diseases and conditions associated with the SK/IK/BK channels.
    Type: Grant
    Filed: May 15, 2001
    Date of Patent: September 23, 2003
    Assignee: Neurosearch A/S
    Inventors: Lene Teuber, Palle Christophersen, Dorte Strobaek, Bo Skaaning Jensen
  • Use of isatin derivatives as ion channel activating agents
    Publication number: 20030114513
    Abstract: The present invention relates to ion channel activating agents. More particularly, the present invention relates to a particular class of chemical compounds that has proven useful as openers of SKCa and IKCa channels. In further aspects, the present invention relates to the use of these SK/IK channel activating agents for the manufacture of medicaments and pharmaceutical compositions comprising the SK/IK channel activating agents.
    Type: Application
    Filed: October 16, 2002
    Publication date: June 19, 2003
    Applicant: NeuroSearch A/S
    Inventors: Bo Skaaning Jensen, Tino Dyhring Jorgensen, Philip K. Ahring, Palle Christophersen, Dorte Strobaek, Lene Teuber, Soren Peter Olesen
  • Bis(benzimidazole) derivatives serving as potassium blocking agents
    Patent number: 6569880
    Abstract: This invention relates to novel potassium channel blocking agents, and their use in the preparation of pharmaceutical compositions.
    Type: Grant
    Filed: February 28, 2002
    Date of Patent: May 27, 2003
    Assignee: Neurosearch A/S
    Inventors: Bo Skaaning Jensen, Søren Peter Olesen, Lene Teuber, Dan Peters, Dorte Strøbæk
  • Use of ion channel modulating agents
    Patent number: 6525043
    Abstract: The present invention relates to the use of a particular class of chemical compounds as modulators of SKCa, IKCa and BKCa channels, and to pharmaceutical compositions comprising the SK/IK/BK channel modulating agents.
    Type: Grant
    Filed: October 25, 2001
    Date of Patent: February 25, 2003
    Assignee: NeuroSearch A/S
    Inventors: Bo Skaaning Jensen, Lene Teuber, Dorte Strobaek, Palle Christophersen, Soren Peter Olesen
  • Ion channel modulating agents
    Publication number: 20030008906
    Abstract: The present invention relates to ion channel modulating agents. More particularly, the present invention relates to a particular class of chemical compounds represented by general formula (I) that has proven useful as modulators of SKCa, IKCa and BKCa channels. In further aspects, the present invention relates to the use of these SK/IK/BK channel modulating agents for the manufacture of medicaments and pharmaceutical compositions comprising the SK/IK/BK channel modulating agents. The SK/IK/BK channel modulating agents of the invention are useful for the treatment or alleviation of diseases and conditions associated with the SK/IK/BK channels.
    Type: Application
    Filed: August 2, 2002
    Publication date: January 9, 2003
    Applicant: Neurosearch A/S
    Inventors: Bo Skaaning Jensen, Lene Teuber, Dorte Strobaek, Palle Christophersen, Soren Peter Olesen
  • Ion channel modulating agents
    Publication number: 20020169203
    Abstract: The present invention relates to ion channel modulating agents. More particularly, the present invention relates to a particular class of chemical compounds that has proven useful as modulators of SK Ca, IK Ca and BK Ca channels. In further aspects, the present invention relates to the use of these SK/IK/BK channel modulating agents for the manufacture of medicaments, for methods of therapy, and pharmaceutical compositions comprising the SK/IK/BK channel modulating agents. The SK/IK/BK channel modulating agents of the invention are useful for the treatment or alleviation of diseases and conditions associated with the SK/IK/BK channels.
    Type: Application
    Filed: May 15, 2001
    Publication date: November 14, 2002
    Inventors: Bo Skaaning Jensen, Dorte Strobaek, Palle Christophersen, Lene Teuber, Jurgen Beyer
  • Ion channel modulating agents
    Patent number: 6458846
    Abstract: The present invention relates to ion channel modulating agents. More particularly, the present invention relates to a particular class of oxime derivatives represented by general formula (I) that has proven useful as modulators of SKCa, IKCa and BKCa channels. In further aspects, the present invention relates to the use of these SK/IK/BK channel modulating agents for the manufacture of medicaments, and pharmaceutical compositions comprising the SK/IK/BK channel modulating agents. The SK/IK/BK channel modulating agents of the invention are useful for the treatment or alleviation of diseases and conditions associated with the SK/IK/BK channels.
    Type: Grant
    Filed: May 15, 2001
    Date of Patent: October 1, 2002
    Assignee: Neurosearch A/S
    Inventors: Bo Skaaning Jensen, Palle Christophersen, Dorte Strobaek, Lene Teuber
  • Potassium channel blocking agents
    Publication number: 20020137784
    Abstract: This invention relates to novel potassium channel blocking agents, and their use in the preparation of pharmaceutical compositions.
    Type: Application
    Filed: February 28, 2002
    Publication date: September 26, 2002
    Applicant: NeuroSearch A/S
    Inventors: Bo Skaaning Jensen, Soren Peter Olesen, Lene Teuber, Dan Peters, Dorte Strobaek
  • Ion channel modulating agents
    Publication number: 20020065315
    Abstract: The present invention relates to ion channel modulating agents. More particularly, the present invention relates to a particular class of chemical compounds represented by general Formula (I) and a pharmaceutically acceptable salt or an oxide or a hydrate thereof, that has proven useful as modulators of SKCa, IKCa and BKCa channels. In further aspects, the present invention relates to the use of these SK/IK/BK channel modulating agents for the manufacture of medicaments, and pharmaceutical compositions comprising the SK/IK/BK channel modulating agents. The SK/IK/BK channel modulating agents of the invention are useful for the treatment or alleviation of diseases and conditions associated with the SK/IK/BK channels.
    Type: Application
    Filed: November 9, 2001
    Publication date: May 30, 2002
    Inventors: Bo Skaaning Jensen, Lene Teuber, Dorte Strobaek, Palle Christophersen, Soren Peter Olesen
  • Use of ion channel modulating agents
    Publication number: 20020065266
    Abstract: The present invention relates to the use of a particular class of chemical compounds as modulators of SKCa, IKCa and BKCa channels, and to pharmaceutical compositions comprising the SK/IK/BK channel modulating agents.
    Type: Application
    Filed: October 25, 2001
    Publication date: May 30, 2002
    Inventors: Bo Skaaning Jensen, Lene Teuber, Dorte Strobaek, Palle Christophersen, Soren Peter Olesen
  • Chemical compounds having ion channel blocking activity for the treatment of immune dysfunction
    Publication number: 20020065247
    Abstract: The present invention relates to chemical compounds having inhibitory activity on an intermediate conductance Ca2+ activated potassium channel (IKCa), and the use of such compounds for the treatment or alleviation of diseases or conditions relating to immune dysfunction.
    Type: Application
    Filed: November 9, 2001
    Publication date: May 30, 2002
    Inventors: Bo Skaaning Jensen, Soren Peter Olsen, Palle Christophersen
  • Ion channel modulating agents
    Publication number: 20020061914
    Abstract: The present invention relates to ion channel modulating agents. More particularly, the present invention relates to a particular class of chemical compounds represented by general formula (I) that has proven useful as modulators of SKCa, IKCa and BKCa channels. In further aspects, the present invention relates to the use of these SK/IK/BK channel modulating agents for the manufacture of medicaments, and pharmaceutical compositions comprising the SK/IK/BK channel modulating agents. The SK/IK/BK channel modulating agents of the invention are useful for the treatment or alleviation of diseases and conditions associated with the SK/IK/BK channels.
    Type: Application
    Filed: November 9, 2001
    Publication date: May 23, 2002
    Inventors: Bo Skaaning Jensen, Lene Teuber, Dorte Strobaek, Palle Christophersen, Soren Peter Olesen