Publication number: 20220332726
Abstract: A small molecule compound of a NO donor is a compound shown in the following structural formula I or a stereoisomer, a geometric isomer, a tautomer, a racemate, a deuterated isotopic derivative, a hydrate, a solvate, a metabolite, or a pharmaceutically acceptable salt or prodrug thereof; wherein a ring A is a substituted or unsubstituted heteroaromatic ring; X is selected from (CH2); R is a substituent of terminal —O—NO2; R1 is selected from hydrogen, a hydroxyl group, a halogen, an amino group, a cyano group, a substituted or unsubstituted alkyl group, a substituted or unsubstituted alkoxy group, a substituted or unsubstituted alkenyl group, a substituted or unsubstituted alkynyl group, or a substituted or unsubstituted heteroalkyl group; R2 and R3 are each independently selected from hydrogen, a substituted or unsubstituted alkyl group, a substituted or unsubstituted cycloalkyl group, or an amino protecting group.
Type:
Application
Filed:
November 18, 2020
Publication date:
October 20, 2022
Applicant:
VIVAVISION (SHANGHAI) LTD
Inventors:
Wang SHEN, Kui Feng DANG, Chao ZHANG, Chunming CHEN, Li Hong SHAN, Wen DING, Xin WANG, Jia Chen MI, Ya Bo SUN, Xia Xin SHENG, Jia Lei SHEN, YONG LI