Patents by Inventor Bo Ying

Bo Ying has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12594242
    Abstract: Provided herein are lipid compounds that can be used in combination with other lipid components, such as neutral lipids, cholesterol and polymer conjugated lipids, to form lipid nanoparticles for delivery of therapeutic agents (e.g., nucleic acid molecules) for therapeutic or prophylactic purposes, including vaccination. Also provided herein are lipid nanoparticle compositions comprising said lipid compounds.
    Type: Grant
    Filed: March 26, 2024
    Date of Patent: April 7, 2026
    Assignee: SUZHOU ABOGEN BIOSCIENCES CO., LTD.
    Inventors: Bo Ying, Xiulian Wang
  • Publication number: 20250230436
    Abstract: The disclosure relates to novel RNA ribozyme constructs encoding foreign proteins or functional RNAs, with a circularization system based on group I introns, which are capable of self-circularizing with high efficiency without introducing extraneous fragments, as well as to methods of using the constructs to make circular RNAs.
    Type: Application
    Filed: December 29, 2023
    Publication date: July 17, 2025
    Inventors: Shaojun QI, Peng GAO, Bo YING
  • Publication number: 20240269074
    Abstract: Provided herein are lipid compounds that can be used in combination with other lipid components, such as neutral lipids, cholesterol and polymer conjugated lipids, to form lipid nanoparticles for delivery of therapeutic agents (e.g., nucleic acid molecules) for therapeutic or prophylactic purposes, including vaccination. Also provided herein are lipid nanoparticle compositions comprising said lipid compounds.
    Type: Application
    Filed: March 26, 2024
    Publication date: August 15, 2024
    Inventors: Bo YING, Xiulian WANG
  • Publication number: 20240238212
    Abstract: Provided herein are lipid compounds that can be used in combination with other lipid components, such as neutral lipids, cholesterol and polymer conjugated lipids, to form lipid nanoparticles for delivery of therapeutic agents (e.g., nucleic acid molecules) for therapeutic or prophylactic purposes, including vaccination. Also provided herein are lipid nanoparticle compositions comprising said lipid compounds.
    Type: Application
    Filed: January 18, 2023
    Publication date: July 18, 2024
    Inventors: XiuLian WANG, Bo YING
  • Publication number: 20240218399
    Abstract: Provided herein are sphingomyelin-containing compositions, and related nanoparticle compositions, lipid nanoparticles, including lipid raft nanoparticles. Also provided herein are related methods and uses of the nanoparticle compositions for delivering nucleic acid molecules to achieve enhanced nucleic acid expression.
    Type: Application
    Filed: October 7, 2022
    Publication date: July 4, 2024
    Inventors: Dandan LING, Xiaobin PAN, Jerry ZHANG, Bo YING
  • Publication number: 20240131150
    Abstract: Provided herein are therapeutic nucleic acid molecules for managing, preventing and/or treating infectious diseases caused by coronavirus. Also provided herein are therapeutic compositions, including vaccines and lipid nanoparticles, comprising the therapeutic nucleic acids and related therapeutic methods and uses.
    Type: Application
    Filed: December 1, 2023
    Publication date: April 25, 2024
    Inventor: Bo Ying
  • Patent number: 11964052
    Abstract: Provided herein are lipid compounds that can be used in combination with other lipid components, such as neutral lipids, cholesterol and polymer conjugated lipids, to form lipid nanoparticles for delivery of therapeutic agents (e.g., nucleic acid molecules) for therapeutic or prophylactic purposes, including vaccination. Also provided herein are lipid nanoparticle compositions comprising said lipid compounds.
    Type: Grant
    Filed: February 1, 2023
    Date of Patent: April 23, 2024
    Assignee: SUZHOU ABOGEN BIOSCIENCES CO., LTD.
    Inventors: Bo Ying, Xiulian Wang
  • Publication number: 20240042010
    Abstract: Provided herein are therapeutic nucleic acid molecules for managing, preventing and/or treating infectious diseases caused by coronavirus. Also provided herein are therapeutic compositions, including vaccines and lipid nanoparticles, comprising the therapeutic nucleic acids and related therapeutic methods and uses.
    Type: Application
    Filed: November 2, 2022
    Publication date: February 8, 2024
    Inventor: Bo Ying
  • Publication number: 20230348362
    Abstract: Provided herein are lipid compounds that can be used in combination with other lipid components, such as neutral lipids, cholesterol and polymer conjugated lipids, to form lipid nanoparticles for delivery of therapeutic agents (e.g., nucleic acid molecules) for therapeutic or prophylactic purposes, including vaccination. Also provided herein are lipid nanoparticle compositions comprising said lipid compounds.
    Type: Application
    Filed: January 11, 2022
    Publication date: November 2, 2023
    Inventors: Bo YING, Xiulian WANG
  • Publication number: 20230286902
    Abstract: Provided herein are lipids that can be used in combination with other lipid components, such as neutral lipids, cholesterol and polymer conjugated lipids, to form lipid nanoparticles for delivery of therapeutic agents (e.g., nucleic acid molecules) for therapeutic or prophylactic purposes, including vaccination.
    Type: Application
    Filed: August 23, 2022
    Publication date: September 14, 2023
    Inventor: Bo Ying
  • Publication number: 20230277652
    Abstract: Provided herein are therapeutic nucleic acid molecules for managing, preventing and/or treating infectious diseases caused by coronavirus. Also provided herein are therapeutic compositions, including vaccines and lipid nanoparticles, comprising the therapeutic nucleic acids and related therapeutic methods and uses.
    Type: Application
    Filed: November 1, 2022
    Publication date: September 7, 2023
    Inventor: Bo Ying
  • Publication number: 20230233468
    Abstract: Provided herein are lipid compounds that can be used in combination with other lipid components, such as neutral lipids, cholesterol and polymer conjugated lipids, to form lipid nanoparticles for delivery of therapeutic agents (e.g., nucleic acid molecules) for therapeutic or prophylactic purposes, including vaccination. Also provided herein are lipid nanoparticle compositions comprising said lipid compounds.
    Type: Application
    Filed: February 1, 2023
    Publication date: July 27, 2023
    Inventors: Bo YING, Xiulian WANG
  • Publication number: 20230053437
    Abstract: Provided herein are lipid compounds that can be used in combination with other lipid components, such as neutral lipids, cholesterol and polymer conjugated lipids, to form lipid nanoparticles for delivery of therapeutic agents (e.g., nucleic acid molecules) for therapeutic or prophylactic purposes, including vaccination. Also provided herein are lipid nanoparticle compositions comprising said lipid compounds.
    Type: Application
    Filed: August 19, 2021
    Publication date: February 23, 2023
    Inventor: Bo Ying
  • Patent number: 11510977
    Abstract: Provided herein are therapeutic nucleic acid molecules for managing, preventing and/or treating infectious diseases caused by coronavirus. Also provided herein are therapeutic compositions, including vaccines and lipid nanoparticles, comprising the therapeutic nucleic acids and related therapeutic methods and uses.
    Type: Grant
    Filed: January 31, 2022
    Date of Patent: November 29, 2022
    Assignee: Suzhou Abogen Biosciences Co., Ltd.
    Inventor: Bo Ying
  • Publication number: 20220331414
    Abstract: Provided herein are lipid compounds that can be used in combination with other lipid components, such as neutral lipids, cholesterol and polymer conjugated lipids, to form lipid nanoparticles for delivery of therapeutic agents (e.g., nucleic acid molecules) for therapeutic or prophylactic purposes, including vaccination. Also provided herein are lipid nanoparticle compositions comprising said lipids.
    Type: Application
    Filed: June 29, 2021
    Publication date: October 20, 2022
    Inventor: Bo Ying
  • Patent number: 11472766
    Abstract: Provided herein are lipids that can be used in combination with other lipid components, such as neutral lipids, cholesterol and polymer conjugated lipids, to form lipid nanoparticles for delivery of therapeutic agents (e.g., nucleic acid molecules) for therapeutic or prophylactic purposes, including vaccination.
    Type: Grant
    Filed: January 27, 2022
    Date of Patent: October 18, 2022
    Assignee: Suzhou Abogen Biosciences Co., Ltd.
    Inventor: Bo Ying
  • Publication number: 20220305130
    Abstract: Formulations comprising anionic agents such as nucleic acids within a lipid-containing particle methods of formulating a lipid-containing particle comprising an anionic agent such as a nucleic acid, methods for preparing a lipid-containing particle comprising an anionic agent such as a nucleic acid, methods for therapeutic delivery of an anionic agent to a patient in need thereof, where the anionic agent is formulated in a lipid-containing particle as described herein.
    Type: Application
    Filed: June 2, 2022
    Publication date: September 29, 2022
    Inventors: Bob Dale Brown, Bo Ying
  • Publication number: 20220218816
    Abstract: Provided herein are therapeutic nucleic acid molecules for managing, preventing and/or treating infectious diseases caused by coronavirus. Also provided herein are therapeutic compositions, including vaccines and lipid nanoparticles, comprising the therapeutic nucleic acids and related therapeutic methods and uses.
    Type: Application
    Filed: January 31, 2022
    Publication date: July 14, 2022
    Inventor: Bo Ying
  • Patent number: 11351265
    Abstract: Formulations comprising anionic agents such as nucleic acids within a lipid-containing particle methods of formulating a lipid-containing particle comprising an anionic agent such as a nucleic acid, methods for preparing a lipid-containing particle comprising an anionic agent such as a nucleic acid, methods for therapeutic delivery of an anionic agent to a patient in need thereof, where the anionic agent is formulated in a lipid-containing particle as described herein.
    Type: Grant
    Filed: October 19, 2018
    Date of Patent: June 7, 2022
    Assignee: Dicerna Pharmaceuticals, Inc.
    Inventors: Bob Dale Brown, Bo Ying
  • Publication number: 20220153686
    Abstract: Provided herein are lipids that can be used in combination with other lipid components, such as neutral lipids, cholesterol and polymer conjugated lipids, to form lipid nanoparticles for delivery of therapeutic agents (e.g., nucleic acid molecules) for therapeutic or prophylactic purposes, including vaccination.
    Type: Application
    Filed: January 27, 2022
    Publication date: May 19, 2022
    Inventor: Bo Ying