Abstract: An example system includes a processor to receive a plurality of object aspects of an object to be evaluated using a process, a structure of the process, a plurality of extracted facts from documents, a tree related to the plurality of object aspects and the structure, and a thesis for each leaf in the tree. The processor is also to relate the extracted facts to the theses in the tree. The processor is to generate a score for each leaf corresponding to a fact in the tree. The processor is to generate a thesis score and a thesis summary for each thesis based on the scores and the summaries of related facts for each thesis. The processor is to further generate a final score for the object based on the thesis scores.

Abstract: A computer implemented method, computerized apparatus and computer program product for inconsistency detection between structured and non-structured data. The method comprising: automatically determining, by a computer, inconsistencies between fields in electronics records, the fields comprise at least a structured field and a non-structured field, the fields are designed to be able to include overlapping information in structured and non-structured form; and indicating, by the computer, to a user potential inconsistencies. Optionally, the indication uses a visual cue when displaying the electronic record to the user, wherein the visual cue indicates the fields which are determined to comprise inconsistent content.

Abstract: Embodiments of the present invention provide methods, computer program products, and systems for classification and identification of cancer genes while correcting for sample bias for tumor-derived genomic features as well as other biased features using machine learning techniques. Embodiments of the present invention can be used to receive a set of genes that include a first gene and a subset of synthetic genes that include similar features to the first gene and receive a set of gene labels associated with physiological characteristics. Embodiments of the present invention can estimate probabilities that genes in the set of genes are associated with gene labels in the set of gene labels using a machine learning classifier and estimate an effective probability range for the first gene and each gene label based, at least in part, on the first gene's estimated probabilities and the estimated probabilities of one or more of the synthetic genes.

Abstract: A method for identifying cancer driver genes is provided. The method includes receiving at least one patient input file containing information for a mutation variation and/or an expression of the gene, parsing the information from the input file into a data structure, annotating the information with cancer driving related annotation, extracting genetic features related to the patient from the information, and scoring the information with a first probability that the mutation variation drives cancer and/or a set of further probabilities that the expression of the gene drives cancer. The first probability and the set of further probabilities are calculated with a first and second Bayesian Network graphical model, respectively.

Abstract: Embodiments are directed to computer implemented method of assessing a relevancy of a pathway to a disease of interest, the pathway having a source and a target. The method includes developing an impact of the source on the pathway. The method further includes developing a value of targeting, based at least in part on an alteration of the pathway, the pathway with a drug of interest. The method further includes identifying a relationship between the source and the target within the pathway. The method further includes combining: the impact of the source on the pathway; the value of targeting, based at least in part on the alteration of the pathway, the pathway with a drug of interest; and the relationship between the source and the target within the pathway, wherein the combining results in an assessment that represents the relevancy of the pathway to the disease of interest.

Abstract: Embodiments are directed to computer implemented method of assessing a relevancy of a pathway to a disease of interest, the pathway having a source and a target. The method includes developing an impact of the source on the pathway. The method further includes developing a value of targeting, based at least in part on an alteration of the pathway, the pathway with a drug of interest. The method further includes identifying a relationship between the source and the target within the pathway. The method further includes combining: the impact of the source on the pathway; the value of targeting, based at least in part on the alteration of the pathway, the pathway with a drug of interest; and the relationship between the source and the target within the pathway, wherein the combining results in an assessment that represents the relevancy of the pathway to the disease of interest.

Abstract: A method comprising using at least one hardware processor for: computing a tree edit distance between two medical treatment plans; and displaying an output based on the computed tree edit distance. The two medical treatment plans are optionally a recommended treatment plan and an executed treatment plan. The output is optionally indicative of compliance of the executed treatment plan with the recommended treatment plan.

Abstract: Machines, systems and methods for supporting clinical decisions comprises providing a graphical user interface (GUI) to facilitate selection of one or more treatment plans (TPs) for one or more clinical presentations (CPs), wherein data records for the TPs and the CPs are implemented over a data structure that defines one or more relationship between the CPs and the TPs, according to medical guidelines or clinical data, wherein interaction with the GUI allows for filtering through TPs associated with one or more CPs, or filtering through CPs associated with one or more TPs, wherein selecting a CP from among a plurality of the CPs results in display of one or more TPs associated with the selected CP, and wherein cross-referencing between results displayed in response to the selection of the selected CP and TP provides details that help determine one or more relevant TPs for a target CP.

Abstract: A computer implemented method, computerized apparatus and computer program product for inconsistency detection between structured and non-structured data. The method comprising: automatically determining, by a computer, inconsistencies between fields in electronics records, the fields comprise at least a structured field and a non-structured field, the fields are designed to be able to include overlapping information in structured and non-structured form; and indicating, by the computer, to a user potential inconsistencies. Optionally, the indication uses a visual cue when displaying the electronic record to the user, wherein the visual cue indicates the fields which are determined to comprise inconsistent content.

Abstract: A computerized method of generating evidence based case object for a decision support application. The method comprises providing a medical decision point, generating a decision point model mapping between a plurality of patient dependent clinical characteristics and a plurality of treatment options for the medical decision point according to a plurality of guidelines, estimating, using a processor, a plurality of treatment outcomes for each the treatment option, each the treatment outcome being estimated according to an analysis of medical records of a group of patients been at the medical decision point and having a subset of the plurality of patient dependent clinical characteristics selected from a plurality of subsets, and generating evidence based case object which receive patient data having patient dependent clinical characteristics matching one of the plurality of subsets and outputs an estimated prognosis based on a respective treatment outcome from the plurality of treatment outcomes.

Abstract: A computer-implemented method and apparatus, the apparatus comprising an information receiving component, a text presentation component for presenting at least a first part of the information on a first pane as text; a form presentation component for presenting at least a second part of the information as a structured form comprising one or more fields on a second pane; and an update component for updating information displayed in the first pane or the second pane in response to changes entered to information displayed in the second pane or in the first pane, respectively.

Abstract: A computer-implemented method and apparatus for receiving a multiplicity of medical cases associated with a disease, each of the multiplicity of medical cases comprising medical features and assigned treatment, wherein the medical cases are divided into two or more groups such that each of groups is associated with a treatment assigned to medical cases classified into the group; and using the multiplicity of medical cases as divided into the two or more groups, to determine information.

Abstract: Method, system, and computer program product for visualization of patient treatments are provided. The method includes: selecting a patient; retrieving data records of patients with similar conditions requiring treatment to the selected patient; and building a tree structure for display with nodes of treatment options and a temporal axis showing treatment results of the similar patients. The tree structure includes representing side effects of a treatment option at a node including a visualization of the strength of the side effect. The tree structure also includes providing edges between the nodes representing a length to progression of the condition requiring treatment.

Abstract: A multicast host for communicating information published about any one of a set of topics to one or more authorised subscribers to those topics, the set of topics being partitioned into one or more partition elements, each partition element having a partition element encryption key associated therewith, wherein each of the one or more partition elements is a disjoint proper subset of the set of topics, the host comprising: means for receiving information relating to a topic; means for determining a partition element for the topic; means for retrieving a partition element encryption key associated with the partition element; means for encrypting the information with the retrieved partition element encryption key; and means for communicating the information to the one or more authorised subscribers.

Abstract: Method, system, and computer program product for load estimation in a user-based environment. The method includes: inputting a set of time-dependent, raw operational indicators of the environment; creating a load function according to the specific needs of the environment; displaying an estimated load; receiving user feedback on the estimated load; and applying a dynamic learning mechanism to generated a user-tuned load function for estimating load on the environment. The dynamic learning mechanism may be an informative mechanism that supports backtracking to solve user-adaptability problems.

Abstract: An RFID tag is provided including an object ID and a counter. Such an RFID tag may be employed in an RFID tag system including a parent RFID tag having an object ID and a counter, a child RFID tag, and a reader/writer configured to read the object ID and the counter of the parent RFID tag, combine values of the object ID and the counter, and write the combined value to an object ID of the child RFID tag.

Abstract: A variety of techniques are disclosed for efficient liveness monitoring in a reliable publish/subscribe multicast system having at least one broker and at least one subscriber, by: at the broker, sending (310) a status request message to the subscriber, and at the subscriber, sending (350) a status response message to the broker to indicate liveness. Status responses by subscribers may be suppressed when at least a chosen minimum number (>=1) of subscribers send a response. This suppression (320-340) uses a system of “response claim” messages and random back-off timers. These provide the advantage that the efficiency of network usage is improved by reducing the number of unwanted packets that are sent.

Abstract: Systems, methods and computer program products for information sharing are provided. In one embodiment, the method comprises generating metadata associated with content stored in a content repository accessible to a community having a plurality of members, wherein the metadata which is stored in the community's registry, is utilized by a community member to determine attributes associated with the content and its subcontents, such that the community member is provided with access to a compilation of information in the subcontents according to a category of interest and based on information in the metadata, and preferably, the community member generates more metadata which is stored in another community's registry associated with the content such that another community member is provided with access to a second compilation of information in the subcontents.

Abstract: An RFID tag is provided including an object ID and a counter. Such an RFID tag may be employed in an RFID tag system including a parent RFID tag having an object ID and a counter, a child RFID tag, and a reader/writer configured to read the object ID and the counter of the parent RFID tag, combine values of the object ID and the counter, and write the combined value to an object ID of the child RFID tag.

Abstract: A transmission method adjusts the size of aggregated packets based at least on the congestion of a transmitting network device. The adjusting comprises includes aggregating at least two small messages, received from an upper layer, into a packet, providing the packet to a pending queue, passing packets to a network device and selecting packets from the pending queue or the buffer depending on whether or not the pending queue is empty.