Patents by Inventor Boaz Gome

Boaz Gome has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Purification of armodafinil
    Patent number: 7960586
    Abstract: The invention encompasses processes for obtaining pure armodafinil substantially free of disulfide impurities that is suitable for use on an industrial scale. In particular, a processes for purifying armodafinil from bis(diphenylmethyl)disulfide comprising: dissolving crude armodafinil in ethanol to form a solution; adding a solvent selected from the group consisting of linear or branched C5-C8 alkyl, linear or branched C5-C8 ether, and mixtures thereof to the solution to form a reaction mixture; cooling the reaction mixture; and isolating pure armodafinil from the reaction mixture.
    Type: Grant
    Filed: August 18, 2008
    Date of Patent: June 14, 2011
    Assignee: Teva Pharmaceutical Industries Ltd.
    Inventor: Boaz Gome
  • Crystalline ziprasidone HCl and processes for preparation thereof
    Patent number: 7678799
    Abstract: Provided is crystalline ziprasidone HCl and processes for preparation thereof.
    Type: Grant
    Filed: June 3, 2004
    Date of Patent: March 16, 2010
    Assignee: Teva Pharmaceutical Industries Ltd.
    Inventors: Anna Balanov, Judith Aronhime, Boaz Gome, Tamas Koltai, Natalia Shenkar, Marioara Mendelovici, Ehud Amir
  • Polymorphic Form XVI of fexofenadine hydrochloride
    Patent number: 7671071
    Abstract: Provided is a crystalline (polymorphic) form of fexofenadine hydrochloride, denominated fexofenadine hydrochloride Form XVI.
    Type: Grant
    Filed: October 3, 2005
    Date of Patent: March 2, 2010
    Assignee: Teva Pharmaceutical Industries Ltd.
    Inventors: Barnaba Krochmal, Dov Diller, Ben-Zion Dolitzky, Judith Aronhime, Shlomit Wizel, Boaz Gome, Igor Lifshitz
  • Crystalline form of nateglinide
    Patent number: 7534913
    Abstract: Provided are crystalline forms of nateglinide, labeled Forms A, C, D, F, G, I, J, K, L, M, N, O, P, Q, T, U, V, Y, ?, ?, ?, ?, ?, ?, ? and ?, processes for their preparation and processes for preparation of other crystalline forms of nateglinide. Also provided are their pharmaceutical formulations and methods of administration.
    Type: Grant
    Filed: December 24, 2003
    Date of Patent: May 19, 2009
    Assignee: Teva Pharmaceutica Industries Ltd.
    Inventors: Gustavo Frenkel, Boaz Gome, Shlomit Wizel
  • POLYMORPHIC FORM XVI OF FEXOFENADINE HYDROCHLORIDE
    Publication number: 20090054486
    Abstract: Provided is a crystalline (polymorphic) form of fexofenadine hydrochloride, denominated fexofenadine hydrochloride Form XVI.
    Type: Application
    Filed: September 11, 2008
    Publication date: February 26, 2009
    Inventors: Barnaba Krochmal, Dov Diller, Ben-Zion Dolitzky, Judith Aronhime, Shlomit Wizel, Boaz Gome, Igor Lifshitz
  • Purification of armodafinil
    Publication number: 20090048464
    Abstract: The invention encompasses processes for obtaining pure armodafinil substantially free of disulfide impurities that is suitable for use on an industrial scale. In particular, a processes for purifying armodafinil from bis(diphenylmethyl)disulfide comprising: dissolving crude armodafinil in ethanol to form a solution; adding a solvent selected from the group consisting of linear or branched C5-C8 alkyl, linear or branched C5-C8 ether, and mixtures thereof to the solution to form a reaction mixture; cooling the reaction mixture; and isolating pure armodafinil from the reaction mixture.
    Type: Application
    Filed: August 18, 2008
    Publication date: February 19, 2009
    Inventor: Boaz Gome
  • Polymorphic forms of nateglinide
    Publication number: 20080319075
    Abstract: Provides are crystalline forms of nateglinide, labeled Forms A, C, D, F, G, I, J, K, L, M, N, O, P, Q, T, U, V, Y, ?, ?, ?, ?, ?, ?, ? and ?, processes for their preparation and processes for preparation of other crystalline forms of nateglinide. Also provided are their pharmaceutical formulations and methods of administration.
    Type: Application
    Filed: April 23, 2008
    Publication date: December 25, 2008
    Inventors: Ronit Yahalomi, Evgeny Shapiro, Ben-Zion Dolitzky, Igal Gozlan, Boaz Gome, Shlomit Wizel
  • Polymorphic forms of nateglinide
    Patent number: 7420084
    Abstract: Provides are crystalline forms of nateglinide, labeled Forms A, C, D, F, G, I, J, K, L, M, N, 0, P, Q, T, U, V, Y, ?, ?, ?, ?, ?, ?, ? and ?, processes for their preparation and processes for preparation of other crystalline forms of nateglinide. Also provided are their pharmaceutical formulations and methods of administration.
    Type: Grant
    Filed: July 18, 2003
    Date of Patent: September 2, 2008
    Assignee: Teva Pharmaceutical Industries Ltd.
    Inventors: Ronit Yahalomi, Evgeny Shapiro, Ben-Zion Dolitzky, Yigael Gozlan, Boaz Gome, Shlomit Wizel
  • Process for preparing Cinacalcet
    Publication number: 20080146845
    Abstract: The invention provides a process for preparing Cinacalcet base in which a compound VI, having the structure: where X is C1-3 alkylsulfonate, substituted and non-substituted C6-10 aryl sulfonate or halogen, is reacted with (R)-1-Naphthylethylamine and, optionally, a base: 1) under minimal solvent conditions, 2) at a minimum temperature of about 100° C., preferably, greater than 121° C., and, more preferably, at a temperature of greater than 121° C. to about 130° C., and 3) under elevated pressure.
    Type: Application
    Filed: November 20, 2007
    Publication date: June 19, 2008
    Inventors: Boaz Gome, Leonid Levenfeld
  • Polymorphic forms of nateglinide
    Patent number: 7358390
    Abstract: Provides are crystalline forms of nateglinide, labeled Forms A, C, D, F, G, I, J, K, L, M, N, O, P, Q, T, U, V, Y, ?, ?, ?, ?, ?, ?, ? and ?, processes for their preparation and processes for preparation of other crystalline forms of nateglinide. Also provided are their pharmaceutical formulations and methods of administration.
    Type: Grant
    Filed: July 18, 2003
    Date of Patent: April 15, 2008
    Assignee: Teva Pharmaceutical Industries Ltd.
    Inventors: Ronit Yahalomi, Evgeny Shapiro, Ben-Zion Dolitzky, Igal Gozlan, Boaz Gome, Shlomit Wizel
  • Crystalline ziprasidone HCI and processes for preparation thereof
    Publication number: 20070238738
    Abstract: Provided is crystalline ziprasidone HCl and processes for preparation thereof.
    Type: Application
    Filed: May 16, 2007
    Publication date: October 11, 2007
    Inventors: Anna Balanov, Judith Aronhime, Boaz Gome, Tamas Koltai, Natalia Shenkar, Marioara Mendelovici, Ehud Amir
  • Polymorphic forms of nateglinide
    Publication number: 20070004804
    Abstract: Provides are crystalline forms of nateglinide, labeled Forms A, C, D, F, G, I, J, K, L, M, N, 0, P, Q, T, U, V, Y, ?, ?, ?, ?, ?, ?, ?, 2 and ?, processes for their preparation and processes for preparation of other crystalline forms of nateglinide. Also provided are their pharmaceutical formulations and methods of administration.
    Type: Application
    Filed: September 5, 2006
    Publication date: January 4, 2007
    Inventors: Ronit Yahalomi, Evgeny Shapiro, Ben-Zion Dolitzky, Igal Gozlan, Boaz Gome, Shlomit Wizel
  • Polymorphic forms of nateglinide
    Patent number: 7148376
    Abstract: Provides are crystalline forms of nateglinide, labeled Forms A, C, D, F, G, I, J, K, L, M, N, O, P, Q, T, U, V, Y, ?, ?, ?, ?, ?, ?, ? and ?, processes for their preparation and processes for preparation of other crystalline forms of nateglinide. Also provided are their pharmaceutical formulations and methods of administration.
    Type: Grant
    Filed: July 18, 2003
    Date of Patent: December 12, 2006
    Assignee: Teva Pharmaceutical Industries Ltd.
    Inventors: Ronit Yahalomi, Evgeny Shapiro, Ben-Zion Dolitzky, Yigael Gozlan, Boaz Gome
  • Polymorphic form XVI of fexofenadine hydrochloride
    Publication number: 20060217557
    Abstract: Provided is a crystalline (polymorphic) form of fexofenadine hydrochloride, denominated fexofenadine hydrochloride Form XVI.
    Type: Application
    Filed: October 3, 2005
    Publication date: September 28, 2006
    Inventors: Barnaba Krochmal, Dov Diller, Ben-Zion Dolitzky, Judith Aronhime, Shlomit Wizel, Boaz Gome, Igor Lifshitz
  • Polymorphic forms of nateglinide
    Publication number: 20060004102
    Abstract: Provided are crystalline forms of nateglinide and processes for their preparation.
    Type: Application
    Filed: May 9, 2005
    Publication date: January 5, 2006
    Inventors: Shlomit Wizel, Gustavo Frenkel, Boaz Gome
  • Polymorphic forms of nateglinide
    Publication number: 20050090552
    Abstract: Provides are crystalline forms of nateglinide, labeled Forms A, C, D, F, G, I, J, K, L, M, N, 0, P, Q, T, U, V, Y, ?, ?, ?, ?, ?, ?, ? and ?, processes for their preparation and processes for preparation of other crystalline forms of nateglinide. Also provided are their pharmaceutical formulations and methods of administration.
    Type: Application
    Filed: October 23, 2003
    Publication date: April 28, 2005
    Inventors: Ronit Yahalomi, Evgeny Shapiro, Ben-Zion Dolitzky, Igal Gozlan, Boaz Gome
  • Polymorphic forms of nateglinide
    Publication number: 20050075400
    Abstract: Provides are crystalline forms of nateglinide, labeled Forms A, C, D, F, G, I, J, K, L, M, N, O, P, Q, T, U, V, Y, ?, ?, ?, ?, ?, ?, ? and ?, processes for their preparation and processes for preparation of other crystalline forms of nateglinide. Also provided are their pharmaceutical formulations and methods of administration.
    Type: Application
    Filed: July 18, 2003
    Publication date: April 7, 2005
    Inventors: Ronit Yahalomi, Evgeny Shapiro, Ben-Zion Dolitzky, Yigael Gozlan, Boaz Gome
  • Crystalline ziprasidone HCI and processes for preparation thereof
    Publication number: 20050059680
    Abstract: Provided is crystalline ziprasidone HCl and processes for preparation thereof.
    Type: Application
    Filed: June 3, 2004
    Publication date: March 17, 2005
    Inventors: Anna Balanov, Judith Aronhime, Boaz Gome, Tamas Koltai, Natalia Shenkar, Marioara Mendelovici, Ehud Amir
  • Crystalline form of nateglinide
    Publication number: 20050014836
    Abstract: Provided are crystalline forms of nateglinide, labeled Forms A, C, D, F, G, I, J, K, L, M, N, O, P, Q, T, U, V, Y, ?, ?, ?, ?, ?, ?, ? and ?, processes for their preparation and processes for preparation of other crystalline forms of nateglinide. Also provided are their pharmaceutical formulations and methods of administration.
    Type: Application
    Filed: December 24, 2003
    Publication date: January 20, 2005
    Inventors: Gustavo Frenkel, Boaz Gome, Shlomit Wizel
  • Polymorphic forms of nateglinide
    Publication number: 20050014949
    Abstract: Provides are crystalline forms of nateglinide, labeled Forms A, C, D, F, G, I, J, K, L, M, N, O, P, Q, T, U, V, Y, ?, ?, ?, ?, ?, ?, ? and ?, processes for their preparation and processes for preparation of other crystalline forms of nateglinide. Also provided are their pharmaceutical formulations and methods of administration.
    Type: Application
    Filed: July 18, 2003
    Publication date: January 20, 2005
    Inventors: Ronit Yahalomi, Evgeny Shapiro, Ben-Zion Dolitzky, Yigael Gozlan, Boaz Gome