Patents by Inventor Boaz Inbal
Boaz Inbal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230331685Abstract: The present invention relates to novel herbicidally active compounds, agrochemical composition thereof, methods of preparation thereof, and uses thereof for controlling the growth of undesirable plants (e.g., weeds), for example in crop fields.Type: ApplicationFiled: September 22, 2021Publication date: October 19, 2023Applicant: AG Plenus LtdInventors: Boaz INBAL, Ezequiel WEXSELBLATT, Yehoshua FREUD, Yoav ATSMON-RAZ, Yoav, Willms LOTHAR
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Publication number: 20120088793Abstract: Disclosed herein are compounds that may be modulators of 5-HT receptors, and methods of making and using same.Type: ApplicationFiled: December 15, 2011Publication date: April 12, 2012Inventors: Shomir Ghosh, Gali Golan, Boaz Inbal, Vincent Jacques, Mercedes Lobera
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Patent number: 8114894Abstract: Disclosed herein are compounds that may be modulators of 5-HT receptors, and methods of making and using same.Type: GrantFiled: December 3, 2009Date of Patent: February 14, 2012Assignee: Nanotherapeutics, Inc.Inventors: Shomir Ghosh, Gali Golan, Boaz Inbal, Vincent Jacques, Mercedes Lobera
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Publication number: 20110195953Abstract: The invention generally relates to thienopyridinone 5-HT4 receptor modulators, and in particular the use of these compounds and their pharmaceutical compositions, e.g., in the treatment, modulation and/or prevention of physiological conditions associated with serotonin action, such as in treating Alzheimer's disease, cognition disorders, depression, and anxiety.Type: ApplicationFiled: September 30, 2009Publication date: August 11, 2011Applicant: EPIX Delaware, Inc.Inventors: Dale S. Dhanoa, Oren Becker, Silvia Noiman, Pradyumna Mohanty, Dongli Chen, Mercedes Lobera, Laurence Wu, Yael Marantz, Boaz Inbal, Alexander Heifetz, Shay Bar-Haim, Sharon Shacham
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Patent number: 7982040Abstract: The invention relates to 5-HT receptor agonists and partial agonists. Novel thienopyridinone compounds represented by Formula I, and synthesis and uses thereof for treating diseases mediated directly or indirectly by 5-HT receptors, are disclosed. Such conditions include Alzheimer's disease, cognition disorders, irritable bowel syndrome, nausea, emesis, vomiting, prokinesia, gastroesophageal reflux disease, nonulcer dyspepsia, depression, anxiety, urinary incontinence, migraine, arrhythmia, atrial fibrillation, ischemic stroke, gastritis, gastric emptying disorders, feeding disorders, gastrointestinal disorders, constipation, erectile dysfunction, and respiratory depression. Methods of preparation and novel intermediates and pharmaceutical salts thereof are also included.Type: GrantFiled: December 24, 2008Date of Patent: July 19, 2011Assignee: Nanotherapeutics, Inc.Inventors: Dale S. Dhanoa, Oren Becker, Silvia Noiman, Pradyumna Mohanty, Dongli Chen, Mercedes Lobera, Laurence Wu, Yael Marantz, Boaz Inbal, Alexander Heifetz, Shay Bar-Haim, Sharon Shacham
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Publication number: 20110082157Abstract: The invention relates to 5-HT receptor antagonists. Novel piperidinylamino-thieno [2,3-d] pyrimidine compounds represented by Formula I, and synthesis and uses thereof for treating diseases mediated directly or indirectly by 5-HT receptors, are disclosed. Such conditions include central nervous system disorders such as pulmonary arterial hypertension, migraine, hypertension, disorders of the gastrointestinal tract, restenosis, asthma, obstructive airway disease, prostatic hyperplasia and priapism, anxiety, depression, schizophrenia, neural injury and stroke. Methods of preparation and novel intermediates and pharmaceutical salts thereof are also provided.Type: ApplicationFiled: June 8, 2010Publication date: April 7, 2011Inventors: Dale S. Dhanoa, Oren Becker, Silvia Noiman, Sekar A. Reddy, Srinivasa Rao Cheruku, Rosa E. Mele'ndez, Anurag Sharadendu, Dongli Chen, Yael Marantz, Sharon Shacham, Alexander Heifetz, Boaz Inbal, Venkitasamy Kesavan, Shay Bar-Haim
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Publication number: 20100197723Abstract: Disclosed herein are compounds that may be modulators of 5-HT receptors, and methods of making and using same.Type: ApplicationFiled: December 3, 2009Publication date: August 5, 2010Inventors: Shomir GHOSH, Gali Golan, Boaz Inbal, Vincent Jacques, Mercedes Lobera
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Publication number: 20100184749Abstract: Chemokine receptor antagonists, in particular, compounds of Formula (I) that act as antagonists of the chemokine CCR2 receptor, including pharmaceutical compositions and uses thereof to treat or prevent diseases associated with monocyte accumulation, lymphocyte accumulation or leukocyte accumulation are described herein.Type: ApplicationFiled: October 12, 2007Publication date: July 22, 2010Applicant: EPIX Delaware ,Inc.Inventors: Merav Fichman, Rosa E. Melendez, Pradyumna Mohanty, Jian Lin, Dilara McCauley, Boaz Inbal, Mercedes Lobera, Pini Orbach, Ori Kalid, Dongli Chen, Yael Marantz, Michael Xie, Sharon Shacham, Oren Becker
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Publication number: 20100113485Abstract: The invention relates to 5-HT receptor modulators, particularly 5-HT2B antagonists. Novel piperidinylamino-thieno[2,3-d]pyrimidine compounds represented by Formula I, II and III, and uses thereof for treating conditions including pulmonary arterial hypertension, congestive heart failure, and hypertension.Type: ApplicationFiled: October 30, 2009Publication date: May 6, 2010Inventors: Dale S. Dhanoa, Oren Becker, Silvia Noiman, Sekar Reddy Alla, Srinivasa Rao Cheruku, Rosa E. Mele'ndez, Anurag Sharadendu, Dongli Chen, Yael Marantz, Sharon Shacham, Alexander Heifetz, Boaz Inbal, Venkitasamy Kesavan, Shay Bar-Haim
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Patent number: 7612078Abstract: The invention relates to 5-HT receptor modulators, particularly 5-HT2B antagonists. Novel piperidinylamino-thieno[2,3-d]pyrimidine compounds represented by Formula I, II and III, and uses thereof for treating conditions including pulmonary arterial hypertension, congestive heart failure, and hypertension.Type: GrantFiled: March 8, 2005Date of Patent: November 3, 2009Assignee: Epix Delaware, Inc.Inventors: Dale S. Dhanoa, Oren Becker, Silvia Noiman, A. Sekar Reddy, Srinivasa R. Cheruku, Rosa E. Melendez, Anurag Sharadendu, Dongli Chen, Yael Marantz, Sharon Shacham, Alexander Heifetz, Boaz Inbal, Venkitasamy Kesavan, Shay Bar-Haim
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Patent number: 7598265Abstract: The invention generally relates to thienopyridinone 5-HT4 receptor modulators, and in particular the use of these compounds and their pharmaceutical compositions, e.g., in the treatment, modulation and/or prevention of physiological conditions associated with serotonin action, such as in treating Alzheimer's disease, cognition disorders, depression, and anxiety.Type: GrantFiled: November 10, 2005Date of Patent: October 6, 2009Assignee: Epix Delaware, Inc.Inventors: Dale S. Dhanoa, Oren Becker, Silvia Noiman, Pradyumna Mohanty, Dongli Chen, Mercedes Lobera, Laurence Wu, Yael Marantz, Boaz Inbal, Alexander Heifetz, Shay Bar-Haim, Sharon Shacham
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Patent number: 7576211Abstract: The invention relates to 5-HT receptor agonists and partial agonists. Novel thienopyridinone compounds represented by Formula I, and synthesis and uses thereof for treating diseases mediated directly or indirectly by 5-HT receptors, are disclosed. Such conditions include Alzheimer's disease, cognition disorders, irritable bowel syndrome, nausea, emesis, vomiting, prokinesia, gastroesophageal reflux disease, nonulcer dyspepsia, depression, anxiety, urinary incontinence, migraine, arrhythmia, atrial fibrillation, ischemic stroke, gastritis, gastric emptying disorders, feeding disorders, gastrointestinal disorders, constipation, erectile dysfunction, and respiratory depression. Methods of preparation and novel intermediates and pharmaceutical salts thereof are also included.Type: GrantFiled: November 8, 2005Date of Patent: August 18, 2009Assignee: Epix Delaware, Inc.Inventors: Dale S. Dhanoa, Oren Becker, Silvia Noiman, Dongli Chen, Yael Marantz, Sharon Shacham, Alexander Heifetz, Boaz Inbal, Shay Bar-Haim, Pradyumna Mohanty, Mercedes Lobera, Laurence Wu
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Publication number: 20090163537Abstract: The invention relates to 5-HT receptor agonists and partial agonists. Novel thienopyridinone compounds represented by Formula I, and synthesis and uses thereof for treating diseases mediated directly or indirectly by 5-HT receptors, are disclosed. Such conditions include Alzheimer's disease, cognition disorders, irritable bowel syndrome, nausea, emesis, vomiting, prokinesia, gastroesophageal reflux disease, nonulcer dyspepsia, depression, anxiety, urinary incontinence, migraine, arrhythmia, atrial fibrillation, ischemic stroke, gastritis, gastric emptying disorders, feeding disorders, gastrointestinal disorders, constipation, erectile dysfunction, and respiratory depression. Methods of preparation and novel intermediates and pharmaceutical salts thereof are also included.Type: ApplicationFiled: December 24, 2008Publication date: June 25, 2009Inventors: Dale S. Dhanoa, Oren Becker, Silvia Noiman, Pradyumna Mohanty, Dongli Chen, Mercedes Lobera, Laurence Wu, Yael Marantz, Boaz Inbal, Alexander Heifetz, Shay Bar-Haim, Sharon Shacham
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Patent number: 7491727Abstract: The invention relates to 5-HT receptor agonists or antagonists. Novel arylpiperazinyl sulfonamide compounds represented by Formula I, and synthesis and uses thereof for treating diseases including those mediated directly or indirectly by 5-HT receptors, are disclosed. Such conditions include central nervous system disorders such as generalized anxiety disorder, ADD/ADHD, neural injury, stroke, and migraine. Methods of preparation and novel intermediates and pharmaceutical salts thereof are also included.Type: GrantFiled: September 5, 2006Date of Patent: February 17, 2009Assignee: Epix Delaware, Inc.Inventors: Dale S. Dhanoa, Dongli Chen, Oren Becker, Silvia Noiman, Srinivasa R. Cheruku, Yael Marantz, Anurag Sharadendu, Sharon Shacham, Alexander Heifetz, Pradyumna Mohanty, Boaz Inbal, Merav Fichman, Raphael Nudelman, Shay Bar-Haim
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Patent number: 7488731Abstract: The invention relates to 5-HT receptor agonists or antagonists. Novel arylpiperazinyl sulfonamide compounds represented by Formula I, and synthesis and uses thereof for treating diseases including those mediated directly or indirectly by 5-HT receptors, are disclosed. Such conditions include central nervous system disorders such as generalized anxiety disorder, ADD/ADHD, neural injury, stroke, and migraine. Methods of preparation and novel intermediates and pharmaceutical salts thereof are also included.Type: GrantFiled: July 24, 2007Date of Patent: February 10, 2009Assignee: Epix Delaware, Inc.Inventors: Dale S. Dhanoa, Dongli Chen, Oren Becker, Silvia Noiman, Srinivasa R. Cheruku, Yael Marantz, Anurag Sharadendu, Sharon Shacham, Alexander Heifetz, Pradyumna Mohanty, Boaz Inbal, Merav Fichman, Raphael Nudelman, Shay Bar-Haim
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Patent number: 7488736Abstract: The invention relates to 5-HT receptor agonists and partial agonists. Thienopyridinone compounds represented by Formula I, and synthesis and uses thereof for treating diseases mediated directly or indirectly by 5-HT receptors, are disclosed. Such conditions include Alzheimer's disease, cognition disorders, irritable bowel syndrome, nausea, emesis, vomiting, prokinesia, gastroesophageal reflux disease, nonulcer dyspepsia, depression, anxiety, urinary incontinence, migraine, arrhythmia, atrial fibrillation, ischemic stroke, gastritis, gastric emptying disorders, feeding disorders, gastrointestinal disorders, constipation, erectile dysfunction, and respiratory depression. Methods of preparation and novel intermediates and pharmaceutical salts thereof are also included.Type: GrantFiled: September 30, 2004Date of Patent: February 10, 2009Assignee: Epix Delaware, Inc.Inventors: Dale S. Dhanoa, Oren Becker, Silvia Noiman, Pradyumna Mohanty, Dongli Chen, Mercedes Lobera, Laurence Wu, Yael Marantz, Boaz Inbal, Alexander Heifetz, Shay Bar-Haim, Sharon Shacham
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Patent number: 7407966Abstract: The invention relates to 5-HT4 receptor agonists and partial agonists. Thienopyridinone compounds and synthesis and uses thereof for treating diseases mediated directly or indirectly by 5-HT4 receptors, are disclosed. Such conditions include Alzheimer's disease, cognition disorders, irritable bowel syndrome, Parkinson's disease, nausea, emesis, vomiting, prokinesia, gastroesophageal reflux disease, and nonulcer dyspepsia. Methods of preparation and novel intermediates and pharmaceutical salts thereof are also included.Type: GrantFiled: October 7, 2004Date of Patent: August 5, 2008Assignee: Epix Delaware, Inc.Inventors: Dale S. Dhanoa, Oren Becker, Silvia Noiman, Laurence Wu, Mercedes Lobera, Pradyumna Mohanty, Yael Marantz, Boaz Inbal, Sharon Shacham, Dongli Chen
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Publication number: 20080027066Abstract: The invention relates to 5-HT receptor agonists or antagonists. Novel arylpiperazinyl sulfonamide compounds represented by Formula I, and synthesis and uses thereof for treating diseases including those mediated directly or indirectly by 5-HT receptors, are disclosed. Such conditions include central nervous system disorders such as generalized anxiety disorder, ADD/ADHD, neural injury, stroke, and migraine. Methods of preparation and novel intermediates and pharmaceutical salts thereof are also included.Type: ApplicationFiled: July 24, 2007Publication date: January 31, 2008Inventors: Dale Dhanoa, Dongli Chen, Oren Becker, Silvia Noiman, Srinivasa Cheruku, Yael Marantz, Anurag Sharadendu, Sharon Shacham, Alexander Heifetz, Pradyumna Mohanty, Boaz Inbal, Merav Fichman, Raphael Nudelman, Shay Bar-Haim
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Publication number: 20070004742Abstract: The invention relates to 5-HT receptor agonists or antagonists. Novel arylpiperazinyl sulfonamide compounds represented by Formula I, and synthesis and uses thereof for treating diseases including those mediated directly or indirectly by 5-HT receptors, are disclosed. Such conditions include central nervous system disorders such as generalized anxiety disorder, ADD/ADHD, neural injury, stroke, and migraine. Methods of preparation and novel intermediates and pharmaceutical salts thereof are also included.Type: ApplicationFiled: September 5, 2006Publication date: January 4, 2007Inventors: Dale Dhanoa, Dongli Chen, Oren Becker, Silvia Noiman, Srinivasa Cheruku, Yael Marantz, Anurag Sharadendu, Sharon Shachem, Alexander Heifetz, Pradyumna Mohanty, Boaz Inbal, Merav Fichman, Raphael Nudelman, Shay Bar-Haim
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Patent number: 7153858Abstract: The invention relates to 5-HT receptor agonists or antagonists. Novel arylpiperazinyl sulfonamide compounds represented by Formulae I: and II, and synthesis and uses of those compounds for treating diseases including those mediated directly or indirectly by 5-HT receptors, are disclosed. Such conditions include central nervous system disorders such as generalized anxiety disorder, ADD/ADHD, neural injury, stroke, and migraine. Methods of preparation and novel intermediates and pharmaceutical salts thereof are also included.Type: GrantFiled: January 30, 2004Date of Patent: December 26, 2006Assignee: Epix Delaware, Inc.Inventors: Dale S. Dhanoa, Dongli Chen, Oren Becker, Silvia Noiman, Srinivasa Rao Cheruku, Yael Marantz, Anurag Sharadendu, Sharon Shachem, Alexander Heifetz, Pradyumna Mohanty, Boaz Inbal, Merav Fichman, Raphael Nudelman, Shay Bar-Haim